Search Results - "Jong, Monique C."

Pretreatment microRNA Expression Impacting on Epithelial-to-Mesenchymal Transition Predicts Intrinsic Radiosensitivity in Head and Neck Cancer Cell Lines and Patients by de Jong, Monique C, Ten Hoeve, Jelle J, Grénman, Reidar, Wessels, Lodewyk F, Kerkhoven, Ron, Te Riele, Hein, van den Brekel, Michiel W M, Verheij, Marcel, Begg, Adrian C

“…Predominant causes of head and neck cancer recurrence after radiotherapy are rapid repopulation, hypoxia, fraction of cancer stem cells, and intrinsic…”
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Unexpected toxicity of CDK4/6 inhibitor palbociclib and radiotherapy by Aken, Evert S. M., Beeker, Aart, Houtenbos, Ilse, Pos, Floris J., Linn, Sabine C., Elkhuizen, Paula H. M., Jong, Monique C.

“…Background Cyclin‐dependent kinase (CDK) 4/6 inhibitors have recently been approved for the treatment of hormone receptor–positive and HER2‐negative metastatic…”
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CD44 Expression Predicts Local Recurrence after Radiotherapy in Larynx Cancer by DE JONG, Monique C, PRAMANA, Jimmy, JANSEN, Jeroen C, RASCH, Coen R, VAN VELTHUYSEN, Marie-Louise F, GRENMAN, Reidar, HOEBERS, Frank J, SCHUURING, Ed, VAN DEN BREKEL, Michiel W, BEGG, Adrian C, VAN DER WAL, Jacqueline E, LACKO, Martin, PEUTZ-KOOTSTRA, Carine J, DE JONG, Jos M, TAKES, Robert P, KAANDERS, Johannes H, VAN DER LAAN, Bernard F, WACHTERS, Jasper

“…To find molecular markers from expression profiling data to predict recurrence of laryngeal cancer after radiotherapy. We generated gene expression data on…”
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Biological Determinants of Chemo-Radiotherapy Response in HPV-Negative Head and Neck Cancer: A Multicentric External Validation by van der Heijden, Martijn, Essers, Paul B M, de Jong, Monique C, de Roest, Reinout H, Sanduleanu, Sebastian, Verhagen, Caroline V M, Hamming-Vrieze, Olga, Hoebers, Frank, Lambin, Philippe, Bartelink, Harry, Leemans, C René, Verheij, Marcel, Brakenhoff, Ruud H, van den Brekel, Michiel W M, Vens, Conchita

“…Tumor markers that are related to hypoxia, proliferation, DNA damage repair and stem cell-ness, have a prognostic value in advanced stage HNSCC patients when…”
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Synergizing systemic responses by combining immunotherapy with radiotherapy in metastatic non-small cell lung cancer: The potential of the abscopal effect by Theelen, Willemijn SME, de Jong, Monique C, Baas, Paul

“…•Immune checkpoint inhibitors are the new cornerstone of metastatic NSCLC treatment.•Several tumor immune escape mechanisms causing failure to ICIs have been…”
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Hypofractionated radiotherapy combined with targeted therapy or immunotherapy: Dutch survey on current practice, knowledge and challenges by van Aken, Evert S.M., van der Linden, Yvette M., van Thienen, Johannes V., de Langen, Adrianus J., Marijnen, Corrie A.M., de Jong, Monique C.

“…•Radiotherapy referral during targeted therapy or immunotherapy occurs regularly.•There is a knowledge gap regarding the implications of combined…”
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ATG12 deficiency results in intracellular glutamine depletion, abrogation of tumor hypoxia and a favorable prognosis in cancer by Keulers, Tom G., Koch, Alexander, van Gisbergen, Marike W., Barbeau, Lydie M.O., Zonneveld, Marijke I., de Jong, Monique C., Savelkouls, Kim G.M., Wanders, Roel G., Bussink, Johan, Melotte, Veerle, Rouschop, Kasper M.A.

“…Hypoxia is a common feature of solid tumors and is associated with increased tumor progression, resistance to therapy and increased metastasis. Hence, tumor…”
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ACLY (ATP Citrate Lyase) Mediates Radioresistance in Head and Neck Squamous Cell Carcinomas and is a Novel Predictive Radiotherapy Biomarker by Göttgens, Eva-Leonne, van den Heuvel, Corina Nam, de Jong, Monique C, Kaanders, Johannes Ham, Leenders, William Pj, Ansems, Marleen, Bussink, Johan, Span, Paul N

“…Radiotherapy is an important treatment modality of head and neck squamous cell carcinomas (HNSCC). Multiple links have been described between the metabolic…”
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The autophagy associated gene, ULK1, promotes tolerance to chronic and acute hypoxia by Schaaf, Marco B.E, Cojocari, Dan, Keulers, Tom G, Jutten, Barry, Starmans, Maud H, de Jong, Monique C, Begg, Adrian C, Savelkouls, Kim G.M, Bussink, Johan, Vooijs, Marc, Wouters, Bradly G, Rouschop, Kasper M.A

“…Abstract Background and purpose Tumor hypoxia is associated with therapy resistance and malignancy. Previously we demonstrated that activation of autophagy and…”
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Development and validation of a nomogram for prediction of survival and local control in laryngeal carcinoma patients treated with radiotherapy alone: A cohort study based on 994 patients by Egelmeer, Ada G.T.M, Velazquez, E. Rios, de Jong, Jos M.A, Oberije, Cary, Geussens, Yasmyne, Nuyts, Sandra, Kremer, Bernd, Rietveld, Derek, René Leemans, C, de Jong, Monique C, Rasch, Coen, Hoebers, Frank, Homer, Jarrod, Slevin, Nick, West, Catharine, Lambin, Philippe

“…Abstract Introduction To advise laryngeal carcinoma patients on the most appropriate form of treatment, a tool to predict survival and local control is needed…”
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Acute Hypoxia Profile is a Stronger Prognostic Factor than Chronic Hypoxia in Advanced Stage Head and Neck Cancer Patients by van der Heijden, Martijn, de Jong, Monique C, Verhagen, Caroline V M, de Roest, Reinout H, Sanduleanu, Sebastian, Hoebers, Frank, Leemans, C René, Brakenhoff, Ruud H, Vens, Conchita, Verheij, Marcel, van den Brekel, Michiel W M

“…Hypoxic head and neck tumors respond poorly to radiotherapy and can be identified using gene expression profiles. However, it is unknown whether treatment…”
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Stereotactic ablative body radiotherapy (SABR) combined with immunotherapy (L19-IL2) versus standard of care in stage IV NSCLC patients, ImmunoSABR: a multicentre, randomised controlled open-label phase II trial by Lieverse, Relinde I Y, Van Limbergen, Evert J, Oberije, Cary J G, Troost, Esther G C, Hadrup, Sine R, Dingemans, Anne-Marie C, Hendriks, Lizza E L, Eckert, Franziska, Hiley, Crispin, Dooms, Christophe, Lievens, Yolande, de Jong, Monique C, Bussink, Johan, Geets, Xavier, Valentini, Vincenzo, Elia, Giuliano, Neri, Dario, Billiet, Charlotte, Abdollahi, Amir, Pasquier, David, Boisselier, Pierre, Yaromina, Ala, De Ruysscher, Dirk, Dubois, Ludwig J, Lambin, Philippe

“…About 50% of non-small cell lung cancer (NSCLC) patients have metastatic disease at initial diagnosis, which limits their treatment options and, consequently,…”
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HPV and high-risk gene expression profiles predict response to chemoradiotherapy in head and neck cancer, independent of clinical factors by de Jong, Monique C, Pramana, Jimmy, Knegjens, Joost L, Balm, Alfons J.M, van den Brekel, Michiel W.M, Hauptmann, Michael, Begg, Adrian C, Rasch, Coen R.N

“…Abstract Purpose The purpose of this study was to combine gene expression profiles and clinical factors to provide a better prediction model of local control…”
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OP040 by Mooren, Jeroen J, Pramana, Jimmy, de Jong, Monique C, van de Brekel, Michiel W, van Velthuysen, M. Loes, Kremer, Bernd, Begg, Adrian C, Speel, Ernst-Jan M

“…Purpose Head and Neck squamous cell carcinoma is the sixth most common cancer in the world. Half of these patients have advanced disease. In these cases…”
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326: ESMO-ESTRO consensus recommendations on the safety of combining targeted therapies with radiotherapy by van Aken, Evert S.M., De Ruysscher, Dirk, Barriuso, Jorge, Castelo-Branco, Luis, Devnani, Bharti, Gandhi, Ajeet K., O'Cathail, Sean M., Prelaj, Arsela, Belka, Claus, Lordick, Florian, Marijnen, Corrie A.M., Ricardi, Umberto, de Jong, Monique C., Pentheroudakis, George

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Stereotactic ablative body radiotherapy versus standard of care in stage IV NSCLC patients, ImmunoSABR: a multicentre, randomised controlled open-label phase II trial by Lieverse, Relinde I. Y, Van Limbergen, Evert J, Oberije, Cary J. G, Troost, Esther G. C, Hadrup, Sine R, Dingemans, Anne-Marie C, Hendriks, Lizza E. L, Eckert, Franziska, Hiley, Crispin, Dooms, Christophe, Lievens, Yolande, de Jong, Monique C, Bussink, Johan, Geets, Xavier, Valentini, Vincenzo, Elia, Giuliano, Neri, Dario, Billiet, Charlotte, Abdollahi, Amir, Pasquier, David, Boisselier, Pierre, Yaromina, Ala, De Ruysscher, Dirk, Dubois, Ludwig J, Lambin, Philippe

“…About 50% of non-small cell lung cancer (NSCLC) patients have metastatic disease at initial diagnosis, which limits their treatment options and, consequently,…”
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OP040: EGFR overexpression predicts unfavourable survival in advanced HPV-positive oropharyngeal cancer treated by chemoradiation therapy by Mooren, Jeroen J., Pramana, Jimmy, de Jong, Monique C., van de Brekel, Michiel W., van Velthuysen, M. Loes, Kremer, Bernd, Begg, Adrian C., Speel, Ernst-Jan M.

“…Head and Neck squamous cell carcinoma is the sixth most common cancer in the world. Half of these patients have advanced disease. In these cases chemoradiation…”
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