Search Results - "Jong, G. de"
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Extracellular vesicle-based therapeutics: natural versus engineered targeting and trafficking
Published in Experimental & molecular medicine (01-03-2019)“…Extracellular vesicles (EVs) are increasingly being recognized as mediators of intercellular signaling via the delivery of effector molecules. Interestingly,…”
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A CRISPR-Cas9-based reporter system for single-cell detection of extracellular vesicle-mediated functional transfer of RNA
Published in Nature communications (28-02-2020)“…Extracellular vesicles (EVs) form an endogenous transport system for intercellular transfer of biological cargo, including RNA, that plays a pivotal role in…”
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Functional Delivery of Lipid-Conjugated siRNA by Extracellular Vesicles
Published in Molecular therapy (05-07-2017)“…Extracellular vesicles (EVs) are cell-derived, membranous nanoparticles that mediate intercellular communication by transferring biomolecules, including…”
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Extracellular vesicles as drug delivery systems: Why and how?
Published in Advanced drug delivery reviews (2020)“…Over the past decades, a multitude of synthetic drug delivery systems has been developed and introduced to the market. However, applications of such systems…”
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Selective breeding as a mitigation tool for methane emissions from dairy cattle
Published in Animal (Cambridge, England) (01-12-2021)“…The global livestock sector, particularly ruminants, contributes substantially to the total anthropogenic greenhouse gases. Management and dietary solutions to…”
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Assessing Sensitive Consumer Behavior Using the Item Count Response Technique
Published in Journal of marketing research (01-06-2019)“…The authors propose a new truth-telling technique and statistical model called "item count response technique" (ICRT) to assess the prevalence and drivers of…”
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Socially Desirable Response Tendencies in Survey Research
Published in Journal of marketing research (01-04-2010)“…Socially desirable responding (SDR) has been of long-standing interest to the field of marketing. Unfortunately, the construct has not always been well…”
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Easy Access to Phosphine‐Borane Building Blocks
Published in Chemistry : a European journal (04-12-2020)“…In this paper, we highlight the synthesis of a variety of primary phosphine‐boranes (RPH2⋅BH3) from the corresponding dichlorophosphines, simply by using…”
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A review on imaging techniques and quantitative measurements for dynamic imaging of cerebral aneurysm pulsations
Published in Scientific reports (26-01-2021)“…Measurement of intracranial aneurysm wall motion may refine the current rupture risk estimation. A golden standard for measuring aneurysm pulsation is lacking…”
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Capillary electrophoresis-mass spectrometry using noncovalently coated capillaries for the analysis of biopharmaceuticals
Published in Analytical and bioanalytical chemistry (01-04-2011)“…In this work, the usefulness of capillary electrophoresis-electrospray ionization time-of-flight-mass spectrometry for the analysis of biopharmaceuticals was…”
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The emerging role of galectins in (re)myelination and its potential for developing new approaches to treat multiple sclerosis
Published in Cellular and molecular life sciences : CMLS (01-04-2020)“…Multiple sclerosis (MS) is an inflammatory, demyelinating and neurodegenerative disease of the central nervous system with unknown etiology. Currently approved…”
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Exploring interactions between extracellular vesicles and cells for innovative drug delivery system design
Published in Advanced drug delivery reviews (01-06-2021)“…[Display omitted] Extracellular vesicles (EVs) are submicron cell-secreted structures containing proteins, nucleic acids and lipids. EVs can functionally…”
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Intermediate-term outcome of cryoballoon ablation of persistent atrial fibrillation and improvements in quality of life of patients
Published in PloS one (21-01-2022)“…Clinical outcome of pulmonary vein isolation (PVI) has been predominantly focused on the reoccurrence of atrial fibrillation (AF) and the maintenance of sinus…”
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Natural or Synthetic RNA Delivery: A Stoichiometric Comparison of Extracellular Vesicles and Synthetic Nanoparticles
Published in Nano letters (24-02-2021)“…RNA therapeutics have high potential that is yet to be fully realized, largely due to challenges involved in the appropriate delivery to target cells…”
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Relaxing Measurement Invariance in Cross‐National Consumer Research Using a Hierarchical IRT Model
Published in The Journal of consumer research (01-08-2007)“…With the growing interest of consumer researchers to test measures and theories in an international context, the cross‐national invariance of measurement…”
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Expression of PD-L1 and PD-L2 on human macrophages is up-regulated by HIV-1 and differentially modulated by IL-10
Published in Journal of leukocyte biology (01-04-2011)“…Monocyte‐derived macrophages up‐regulate PD‐L1 but not PD‐L2 in response to autocrine IL‐10, and up‐regulate both PD‐L1 and PD‐L2 in response to HIV. PD‐1…”
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Using Item Response Theory to Measure Extreme Response Style in Marketing Research: A Global Investigation
Published in Journal of marketing research (01-02-2008)“…Extreme response style (ERS) is an important threat to the validity of survey-based marketing research. In this article, the authors present a new item…”
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Genetic analysis of longevity in Dutch dairy cattle using random regression
Published in Journal of dairy science (01-06-2015)“…Longevity, productive life, or lifespan of dairy cattle is an important trait for dairy farmers, and it is defined as the time from first calving to the last…”
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Alternative somatic cell count traits as mastitis indicators for genetic selection
Published in Journal of dairy science (01-06-2008)“…The aim of this study was to define alternative traits of somatic cell count (SCC) that can be used to decrease genetic susceptibility to clinical and…”
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Simultaneous Assessment of Protein Heterogeneity and Affinity by Capillary Electrophoresis–Mass Spectrometry
Published in Analytical chemistry (Washington) (01-09-2015)“…Most conventional analytical tools for the assessment of protein–protein interactions yield information on the bulk sample. By employing the efficient…”
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