Search Results - "Jong, Dirk J de"
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Genetic deficiency of NOD2 confers resistance to invasive aspergillosis
Published in Nature communications (06-07-2018)“…© The Author(s) 2018. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing,…”
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Prevalence of-and risk factors for work disability in Dutch patients with inflammatory bowel disease
Published in World journal of gastroenterology : WJG (14-12-2017)“…AIM To determine the prevalence of work disability in inflammatory bowel disease(IBD), and to assess risk factors associated with work disability.METHODS For…”
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NOD2 mediates anti‐inflammatory signals induced by TLR2 ligands: implications for Crohn's disease
Published in European Journal of Immunology (01-07-2004)“…Mutations of the NOD2 gene have been associated with an increased susceptibility to Crohn's disease, but the pathogenetic mechanisms mediated by NOD2 remain…”
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Reduced late rectal mucosal changes after prostate three-dimensional conformal radiotherapy with endorectal balloon as observed in repeated endoscopy
Published in International journal of radiation oncology, biology, physics (01-03-2007)“…Purpose: The aim of this study was to investigate prospectively the rectal wall (Rwall) spatial dose distribution, toxicity, and mucosal changes after prostate…”
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Genetic association analysis of the functional c.714T>G polymorphism and mucosal expression of dectin-1 in inflammatory bowel disease
Published in PloS one (12-11-2009)“…Dectin-1 is a pattern recognition receptor (PRR) expressed by myeloid cells that specifically recognizes beta-1,3 glucan, a polysaccharide and major component…”
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GST Theta null genotype is associated with an increased risk for ulcerative colitis: a case-control study and meta-analysis of GST Mu and GST Theta polymorphisms in inflammatory bowel disease
Published in Journal of human genetics (01-10-2014)“…Glutathione S-transferases (GSTs) are important in the detoxification of many compounds, including reactive oxygen species. Polymorphisms in GSTs resulting in…”
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Pooled Resequencing of 122 Ulcerative Colitis Genes in a Large Dutch Cohort Suggests Population-Specific Associations of Rare Variants in MUC2
Published in PloS one (04-08-2016)“…Genome-wide association studies have revealed several common genetic risk variants for ulcerative colitis (UC). However, little is known about the contribution…”
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High mucosal healing rates in 5‐ASA‐treated ulcerative colitis patients: Results of a meta‐analysis of clinical trials
Published in Inflammatory bowel diseases (01-11-2012)“…Background: Recently, mucosal healing (MH) is regarded as an important treatment goal in ulcerative colitis (UC). 5‐Aminosalicylates (5‐ASA) are the standard…”
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NOD2 and toll-like receptors are nonredundant recognition systems of Mycobacterium tuberculosis
Published in PLoS pathogens (01-11-2005)“…Infection with Mycobacterium tuberculosis is one of the leading causes of death worldwide. Recognition of M. tuberculosis by pattern recognition receptors is…”
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Cohort profile: design and first results of the Dutch IBD Biobank: a prospective, nationwide biobank of patients with inflammatory bowel disease
Published in BMJ open (01-11-2017)“…PurposeThe Dutch IBD Biobank aims to facilitate the discovery of predictors for individual disease course and treatment response in patients with inflammatory…”
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Recognition of Coxiella burnetii by Toll-like Receptors and Nucleotide-Binding Oligomerization Domain-like Receptors
Published in The Journal of infectious diseases (15-03-2015)“…Background. Infection with Coxiella burnetii can lead to acute and chronic Q fever. Toll-like receptor 1 (TLR1), TLR2, TLR4, TLR6, nucleotide-binding…”
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Nucleotide-Binding Oligomerization Domain-2 Modulates Specific TLR Pathways for the Induction of Cytokine Release
Published in The Journal of immunology (1950) (15-05-2005)“…The recognition of peptidoglycan by cells of the innate immune system has been controversial; both TLR2 and nucleotide-binding oligomerization domain-2 (NOD2)…”
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On tolerability and safety of a maintenance treatment with 6-thioguanine in azathioprine or 6-mercaptopurine intolerant IBD patients
Published in World journal of gastroenterology : WJG (21-09-2005)“…To determine the tolerability and safety profile of a low-dose maintenance therapy with 6-TG in azathioprine (AZA) or 6-mercaptopurine (6-MP) intolerant…”
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Mycobacterium paratuberculosis is recognized by Toll-like receptors and NOD2
Published in Journal of leukocyte biology (01-10-2007)“…Mycobacterium paratuberculosis has been suggested to be involved in the pathogenesis of Crohn's disease (CD). The importance of microorganisms in CD is…”
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LPS-Stimulated Whole Blood Cytokine Production Is Not Related to Disease Behavior in Patients with Quiescent Crohn's Disease
Published in PloS one (24-07-2015)“…Crohn's disease (CD) is a chronic inflammatory disease in which cytokines play a pivotal role in the induction and maintenance of inflammation. Innate cytokine…”
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Differential Toll-Like Receptor Recognition and Induction of Cytokine Profile by Bifidobacterium breve and Lactobacillus Strains of Probiotics
Published in Clinical and Vaccine Immunology (01-04-2011)“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Impaired dendritic cell function in Crohn’s disease patients with NOD2 3020insC mutation
Published in Journal of leukocyte biology (01-04-2006)“…The nucleotide oligomerization domain 2 (NOD2) 3020insC (NOD2fs) mutation increases susceptibility to Crohn’s disease (CD), but the mechanism remains…”
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Malignant transformation of perianal and enterocutaneous fistulas is rare: results of 17 years of follow-up from The Netherlands
Published in Scandinavian journal of gastroenterology (01-03-2011)“…Abstract Objective. Malignant transformation of fistulas has been observed, particularly in perianal fistulas in Crohn's disease (CD) patients. The prevalence…”
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Effect of childbirth on the course of Crohn's disease; results from a retrospective cohort study in the Netherlands
Published in BMC gastroenterology (26-01-2011)“…Pregnant women with Crohn's disease needs proper counselling about the effect of pregnancy and childbirth on their disease. However, Literature about the…”
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Association between toll‐like receptor 4 and inflammatory bowel disease
Published in Inflammatory bowel diseases (01-06-2005)“…Background: The human Toll‐like receptor 4 (TLR4) participates in the innate response. Recently, the TLR4 variant Asp299Gly has been described to affect the…”
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