Search Results - "Jones Steven"

CancerMine: a literature-mined resource for drivers, oncogenes and tumor suppressors in cancer by Lever, Jake, Zhao, Eric Y., Grewal, Jasleen, Jones, Martin R., Jones, Steven J. M.

“…Tumors from individuals with cancer are frequently genetically profiled for information about the driving forces behind the disease. We present the CancerMine…”
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Whole-Genome Sequencing and Social-Network Analysis of a Tuberculosis Outbreak by Gardy, Jennifer L, Johnston, James C, Sui, Shannan J. Ho, Cook, Victoria J, Shah, Lena, Brodkin, Elizabeth, Rempel, Shirley, Moore, Richard, Zhao, Yongjun, Holt, Robert, Varhol, Richard, Birol, Inanc, Lem, Marcus, Sharma, Meenu K, Elwood, Kevin, Jones, Steven J.M, Brinkman, Fiona S.L, Brunham, Robert C, Tang, Patrick

“…An outbreak of tuberculosis occurred over a 3-year period in a medium-size community in British Columbia, Canada. The results of mycobacterial interspersed…”
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Tigmint: correcting assembly errors using linked reads from large molecules by Jackman, Shaun D, Coombe, Lauren, Chu, Justin, Warren, Rene L, Vandervalk, Benjamin P, Yeo, Sarah, Xue, Zhuyi, Mohamadi, Hamid, Bohlmann, Joerg, Jones, Steven J M, Birol, Inanc

“…Genome sequencing yields the sequence of many short snippets of DNA (reads) from a genome. Genome assembly attempts to reconstruct the original genome from…”
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ORegAnno 3.0: a community-driven resource for curated regulatory annotation by Lesurf, Robert, Cotto, Kelsy C, Wang, Grace, Griffith, Malachi, Kasaian, Katayoon, Jones, Steven J M, Montgomery, Stephen B, Griffith, Obi L

“…The Open Regulatory Annotation database (ORegAnno) is a resource for curated regulatory annotation. It contains information about regulatory regions,…”
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Population sequencing reveals clonal diversity and ancestral inbreeding in the grapevine cultivar Chardonnay by Roach, Michael J, Johnson, Daniel L, Bohlmann, Joerg, van Vuuren, Hennie J J, Jones, Steven J M, Pretorius, Isak S, Schmidt, Simon A, Borneman, Anthony R

“…Chardonnay is the basis of some of the world's most iconic wines and its success is underpinned by a historic program of clonal selection. There are numerous…”
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Conserved role of intragenic DNA methylation in regulating alternative promoters by Maunakea, Alika K., Nagarajan, Raman P., Bilenky, Mikhail, Ballinger, Tracy J., D’Souza, Cletus, Fouse, Shaun D., Johnson, Brett E., Hong, Chibo, Nielsen, Cydney, Zhao, Yongjun, Turecki, Gustavo, Delaney, Allen, Varhol, Richard, Thiessen, Nina, Shchors, Ksenya, Heine, Vivi M., Rowitch, David H., Xing, Xiaoyun, Fiore, Chris, Schillebeeckx, Maximiliaan, Jones, Steven J. M., Haussler, David, Marra, Marco A., Hirst, Martin, Wang, Ting, Costello, Joseph F.

“…Methylation in the genes DNA methylation plays an important role in the maintenance of cell identity through its effect on gene expression. Methylation of 5′…”
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A computational approach to finding novel targets for existing drugs by Li, Yvonne Y, An, Jianghong, Jones, Steven J M

“…Repositioning existing drugs for new therapeutic uses is an efficient approach to drug discovery. We have developed a computational drug repositioning pipeline…”
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Perceptions and expectations of autonomous vehicles – A snapshot of vulnerable road user opinion by Penmetsa, Praveena, Adanu, Emmanuel Kofi, Wood, Dustin, Wang, Teng, Jones, Steven L.

“…Public perceptions play a crucial role in wider adoption of autonomous vehicles (AVs). This paper aims to make two contributions to the understanding of public…”
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Mutations in EZH2 Cause Weaver Syndrome by Gibson, William T., Hood, Rebecca L., Zhan, Shing Hei, Bulman, Dennis E., Fejes, Anthony P., Moore, Richard, Mungall, Andrew J., Eydoux, Patrice, Babul-Hirji, Riyana, An, Jianghong, Marra, Marco A., Chitayat, David, Boycott, Kym M., Weaver, David D., Jones, Steven J.M.

“…We used trio-based whole-exome sequencing to analyze two families affected by Weaver syndrome, including one of the original families reported in 1974…”
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ARID1A Mutations in Endometriosis-Associated Ovarian Carcinomas by Wiegand, Kimberly C, Shah, Sohrab P, Al-Agha, Osama M, Zhao, Yongjun, Tse, Kane, Zeng, Thomas, Senz, Janine, McConechy, Melissa K, Anglesio, Michael S, Kalloger, Steve E, Yang, Winnie, Heravi-Moussavi, Alireza, Giuliany, Ryan, Chow, Christine, Fee, John, Zayed, Abdalnasser, Prentice, Leah, Melnyk, Nataliya, Turashvili, Gulisa, Delaney, Allen D, Madore, Jason, Yip, Stephen, McPherson, Andrew W, Ha, Gavin, Bell, Lynda, Fereday, Sian, Tam, Angela, Galletta, Laura, Tonin, Patricia N, Provencher, Diane, Miller, Dianne, Jones, Steven J.M, Moore, Richard A, Morin, Gregg B, Oloumi, Arusha, Boyd, Niki, Aparicio, Samuel A, Shih, Ie-Ming, Mes-Masson, Anne-Marie, Bowtell, David D, Hirst, Martin, Gilks, Blake, Marra, Marco A, Huntsman, David G

“…In this study of ovarian clear-cell or endometrioid tumors, nearly half the samples had mutations in the ARID1A gene, which encodes a component of the SWI–SNF…”
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Megabase-scale methylation phasing using nanopore long reads and NanoMethPhase by Akbari, Vahid, Garant, Jean-Michel, O'Neill, Kieran, Pandoh, Pawan, Moore, Richard, Marra, Marco A, Hirst, Martin, Jones, Steven J M

“…The ability of nanopore sequencing to simultaneously detect modified nucleotides while producing long reads makes it ideal for detecting and phasing…”
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Angiotensinogen Takes Some of the Spotlight From Angiotensin II in the Cardiohepatic Axis by Jones, Steven P.

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MEG3 long noncoding RNA regulates the TGF-β pathway genes through formation of RNA–DNA triplex structures by Mondal, Tanmoy, Subhash, Santhilal, Vaid, Roshan, Enroth, Stefan, Uday, Sireesha, Reinius, Björn, Mitra, Sanhita, Mohammed, Arif, James, Alva Rani, Hoberg, Emily, Moustakas, Aristidis, Gyllensten, Ulf, Jones, Steven J.M., Gustafsson, Claes M, Sims, Andrew H, Westerlund, Fredrik, Gorab, Eduardo, Kanduri, Chandrasekhar

“…Long noncoding RNAs (lncRNAs) regulate gene expression by association with chromatin, but how they target chromatin remains poorly understood. We have used…”
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ABySS: a parallel assembler for short read sequence data by Simpson, Jared T, Wong, Kim, Jackman, Shaun D, Schein, Jacqueline E, Jones, Steven J M, Birol, Inanç

“…Widespread adoption of massively parallel deoxyribonucleic acid (DNA) sequencing instruments has prompted the recent development of de novo short read assembly…”
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O-GlcNAc and the cardiovascular system by DASSANAYAKA, Sujith, JONES, Steven P

“…The cardiovascular system is capable of robust changes in response to physiologic and pathologic stimuli through intricate signaling mechanisms. The area of…”
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Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma by Dubuc, Adrian M., Remke, Marc, Korshunov, Andrey, Northcott, Paul A., Zhan, Shing H., Mendez-Lago, Maria, Kool, Marcel, Jones, David T. W., Unterberger, Alexander, Morrissy, A. Sorana, Shih, David, Peacock, John, Ramaswamy, Vijay, Rolider, Adi, Wang, Xin, Witt, Hendrik, Hielscher, Thomas, Hawkins, Cynthia, Vibhakar, Rajeev, Croul, Sidney, Rutka, James T., Weiss, William A., Jones, Steven J. M., Eberhart, Charles G., Marra, Marco A., Pfister, Stefan M., Taylor, Michael D.

“…Recent sequencing efforts have described the mutational landscape of the pediatric brain tumor medulloblastoma. Although MLL2 is among the most frequent…”
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Drug repositioning for personalized medicine by Li, Yvonne Y, Jones, Steven Jm

“…Human diseases can be caused by complex mechanisms involving aberrations in numerous proteins and pathways. With recent advances in genomics, elucidating the…”
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Assembling the 20 Gb white spruce (Picea glauca) genome from whole-genome shotgun sequencing data by Birol, Inanc, Raymond, Anthony, Jackman, Shaun D, Pleasance, Stephen, Coope, Robin, Taylor, Greg A, Yuen, Macaire Man Saint, Keeling, Christopher I, Brand, Dana, Vandervalk, Benjamin P, Kirk, Heather, Pandoh, Pawan, Moore, Richard A, Zhao, Yongjun, Mungall, Andrew J, Jaquish, Barry, Yanchuk, Alvin, Ritland, Carol, Boyle, Brian, Bousquet, Jean, Ritland, Kermit, Mackay, John, Bohlmann, Jörg, Jones, Steven J M

“…White spruce (Picea glauca) is a dominant conifer of the boreal forests of North America, and providing genomics resources for this commercially valuable tree…”
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Assembling millions of short DNA sequences using SSAKE by Warren, René L., Sutton, Granger G., Jones, Steven J. M., Holt, Robert A.

“…Novel DNA sequencing technologies with the potential for up to three orders magnitude more sequence throughput than conventional Sanger sequencing are…”
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Profiling the HeLa S3 transcriptome using randomly primed cDNA and massively parallel short-read sequencing by Morin, Ryan, Bainbridge, Matthew, Fejes, Anthony, Hirst, Martin, Krzywinski, Martin, Pugh, Trevor, McDonald, Helen, Varhol, Richard, Jones, Steven, Marra, Marco

“…Sequence-based methods for transcriptome characterization have typically relied on generation of either serial analysis of gene expression tags or expressed…”
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