Search Results - "Jones, Y E"

Plexin signaling hampers integrin‐based adhesion, leading to Rho‐kinase independent cell rounding, and inhibiting lamellipodia extension and cell motility by Barberis, D., Artigiani, S., Casazza, A., Corso, S., Giordano, S., Love, C. A., Jones, E. Y., Comoglio, P. M., Tamagnone, L.

“…Plexins encode receptors for semaphorins, molecular signals guiding cell migration, and axon pathfinding. The mechanisms mediating plexin function are poorly…”
Get full text

Crystal structure of the extracellular region of human tissue factor by Harlos, K, Martin, D. M. A, O'Brien, D. P, Jones, E. Y, Stuart, D. I, Polikarpov, I, Miller, A, Tuddenham, E. G. D, Boys, C. W. G

“…Tissue factor is a cell-surface glycoprotein receptor which initiates the blood coagulation cascade after vessel injury by interacting with blood clotting…”
Get full text

Crystal structure of an integrin-binding fragment of vascular cell adhesion molecule-1 at 1.8 Å resolution by Jones, E. Y, Harlos, K, Bottomley, M. J, Robinson, R. C, Driscoll, P. C, Edwards, R. M, Clements, J. M, Dudgeon, T. J, Stuart, D. I

“…The cell-surface glycoprotein vascular cell adhesion molecule-1 (VCAM-1; ref. 1) mediates intercellular adhesion by specific binding to the integrin very-late…”
Get full text

Complexes of HIV-1 Reverse Transcriptase with Inhibitors of the HEPT Series Reveal Conformational Changes Relevant to the Design of Potent Non-Nucleoside Inhibitors by Hopkins, Andrew L, Ren, Jingshan, Esnouf, Robert M, Willcox, Benjamin E, Jones, E. Yvonne, Ross, Carl, Miyasaka, Tadashi, Walker, Richard T, Tanaka, Hiromichi, Stammers, David K, Stuart, David I

“…Crystal structures of HIV-1 reverse transcriptase (RT) complexed with a range of chemically diverse non-nucleoside inhibitors (NNIs) have shown a single pocket…”
Get full text

Structure of tumour necrosis factor by Jones, E. Y, Stuart, D. I, Walker, N. P. C

“…Tumour necrosis factor is a trimeric molecule, each subunit of which consists of an antiparallel beta-sandwich. Individual subunits from the trimer by a novel…”
Get full text

First steps towards effective methods in exploiting high-throughput technologies for the determination of human protein structures of high biomedical value by Banci, L., Bertini, I., Cusack, S., De Jong, R. N., Heinemann, U., Jones, E. Y., Maskos, K., Kozielski, F., Owens, R., Perrakis, A., Siebold, C., Silman, I., Messerschmidt, A., Poterszman, A., Schneider, G., Sixma, T., Sussman, J. L., Stewart-Jones, G., Thierry, J.-C., Moras, Dino

“…The EC `Structural Proteomics In Europe' contract is aimed specifically at the atomic resolution structure determination of human protein targets closely…”
Get full text

Faecal carriage of verocytotoxin-producing Escherichia coli O157 in cattle and sheep at slaughter in Great Britain by Paiba, G A, Gibbens, J C, Pascoe, S J S, Wilesmith, J W, Kidd, S A, Byrne, C, Ryan, J B M, Smith, R P, McLaren, M, Futter, R J, Kay, A C S, Jones, Y E, Chappell, S A, Willshaw, G A, Cheasty, T

“…A 12-month abattoir survey was conducted between January 1999 and January 2000, to determine the prevalence of faecal carriage of verocytotoxin-producing…”
Get full text

Nonstandard Peptide Binding Revealed by Crystal Structures of HLA-B5101 Complexed with HIV Immunodominant Epitopes by Maenaka, Katsumi, Maenaka, Taeko, Tomiyama, Hiroko, Takiguchi, Masafumi, Stuart, David I, Jones, E. Yvonne

“…The crystal structures of the human MHC class I allele HLA-B*5101 in complex with 8-mer, TAFTIPSI, and 9-mer, LPPVVAKEI, immunodominant peptide epitopes from…”
Get full text

Continuous and Discontinuous Changes in the Unit Cell of HIV-1 Reverse Transcriptase Crystals on Dehydration by Esnouf, Robert M., Ren, Jingshan, Garman, Elspeth F., Somers, Don O'N., Ross, Carl K., Jones, E. Yvonne, Stammers, David K., Stuart, David I.

“…A crystal form of HIV‐1 reverse transcriptase (RT) complexed with inhibitors showed diffraction to a high‐resolution limit of 3.7 Å. Instability in the…”
Get full text

Antimicrobial resistance in Salmonella isolated from animals and their environment in England and Wales from 1988 to 1999 by Jones, Y. E., Chappell, S., McLaren, I. M., Davies, R. H., Wray, C.

“…Resistance to 16 antimicrobial agents was monitored in 109,125 Salmonella cultures isolated from animals, their environment and feedstuffs between 1988 and…”
Get full text

The crystal structure and biological function of leukemia inhibitory factor: implications for receptor binding by Robinson, R C, Grey, L M, Staunton, D, Vankelecom, H, Vernallis, A B, Moreau, J F, Stuart, D I, Heath, J K, Jones, E Y

“…The structure of murine leukemia inhibitory factor (LIF) has been determined by X-ray crystallography at 2.0 A resolution. The main chain fold conforms to the…”
Get more information

The structures of the neurotrophin 4 homodimer and the brain-derived neurotrophic factor/neurotrophin 4 heterodimer reveal a common Trk-binding site by ROBINSON, ROBERT C., RADZIEJEWSKI, CZESLAW, SPRAGGON, GLEN, GREENWALD, JASON, KOSTURA, MIKEY R., BURTNICK, LESLIE D., STUART, DAVID I., CHOE, SENYON, JONES, E. YVONNE

“…The neurotrophins are growth factors that are involved in the development and survival of neurons. Neurotrophin release by a target tissue results in neuron…”
Get full text

A procedure for setting up high-throughput nanolitre crystallization experiments. II. Crystallization results by Brown, J., Walter, T. S., Carter, L., Abrescia, N. G. A., Aricescu, A. R., Batuwangala, T. D., Bird, L. E., Brown, N., Chamberlain, P. P., Davis, S. J., Dubinina, E., Endicott, J., Fennelly, J. A., Gilbert, R. J. C., Harkiolaki, M., Hon, W.-C., Kimberley, F., Love, C. A., Mancini, E. J., Manso-Sancho, R., Nichols, C. E., Robinson, R. A., Sutton, G. C., Schueller, N., Sleeman, M. C., Stewart-Jones, G. B., Vuong, M., Welburn, J., Zhang, Z., Stammers, D. K., Owens, R. J., Jones, E. Y., Harlos, K., Stuart, D. I.

“…An initial tranche of results from day‐to‐day use of a robotic system for setting up 100 nl‐scale vapour‐diffusion sitting‐drop protein crystallizations has…”
Get full text

A structural basis for immunodominant human T cell receptor recognition by Jones, E Yvonne, Stewart-Jones, Guillaume B E, McMichael, Andrew J, Bell, John I, Stuart, David I

“…The anti-influenza CD8+ T cell response in HLA-A2-positive adults is almost exclusively directed at residues 58-66 of the virus matrix protein (MP(58-66))…”
Get full text

Human Inhibitory Receptors Ig-like Transcript 2 (ILT2) and ILT4 Compete with CD8 for MHC Class I Binding and Bind Preferentially to HLA-G by Shiroishi, Mitsunori, Tsumoto, Kouhei, Amano, Kimie, Shirakihara, Yasuo, Colonna, Marco, Braud, Veronique M., David S. J. Allan, Makadzange, Azure, Rowland-Jones, Sarah, Willcox, Benjamin, Jones, E. Yvonne, van der Merwe, P. Anton, Kumagai, Izumi, Maenaka, Katsumi

“…Ig-like transcript 4 (ILT4) (also known as leukocyte Ig-like receptor 2, CD85d, and LILRB2) is a cell surface receptor expressed mainly on myelomonocytic…”
Get full text

Crystal structure of the N-terminal domain of sialoadhesin in complex with 3' sialyllactose at 1.85 A resolution by May, A P, Robinson, R C, Vinson, M, Crocker, P R, Jones, E Y

“…The structure of the functional N-terminal domain from the extracellular region of the cell surface receptor sialoadhesin has been determined in complex with…”
Get full text

Structural basis of superantigen action inferred from crystal structure of toxic-shock syndrome toxin-1 by Acharya, K. Ravi, Passalacqua, Edward F, Jones, E. Yvonne, Harlos, Karl, Stuart, David I, Brehm, Rossalyn D, Tranter, Howard S

“…Superantigens stimulate T cells bearing particular T-cell receptor V beta sequences, so they are extremely potent polyclonal T-cell mitogens. T-cell activation…”
Get full text

A functional and structural basis for TCR cross-reactivity in multiple sclerosis by Jones, E. Yvonne, Fugger, Lars, Lang, Heather L.E, Jacobsen, Helle, Ikemizu, Shinji, Andersson, Christina, Harlos, Karl, Madsen, Lars, Hjorth, Peter, Sondergaard, Leif, Svejgaard, Arne, Wucherpfennig, Kai, Stuart, David I, Bell, John I

“…The multiple sclerosis (MS)-associated HLA major histocompatibility complex (MHC) class II alleles DRB1*1501, DRB5*0101 and DQB1*0602 are in strong linkage…”
Get full text

The epidemiology of Salmonella Typhimurium in cattle: plasmid profile analysis of definitive phage type (DT) 204c by WRAY, C, McLAREN, I. M, JONES, YVETTE E

“…Bacteriology Department, Central Veterinary Laboratory, New Haw, Addlestone, Surrey KT15 3NB Corresponding author: Dr C. Wray. Received May 10, 1997 Accepted…”
Get full text

Increase in Salmonella enterica subspecies diarizonae serovar 61:k:1,5,(7) in sheep by Davies, R H, Evans, S J, Preece, B E, Chappell, S, Kidd, S, Jones, Y E

Get full text