Search Results - "Jones, Tim D."

Understanding “disengagement from knowledge sharing”: engagement theory versus adaptive cost theory by Ford, Dianne, Myrden, Susan E, Jones, Tim D

“…Purpose – The purpose of this paper is using competing hypotheses (a spillover hypothesis, based on Engagement Theory, and a provisioning hypothesis, based on…”
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Mantle sources of ocean islands basalts revealed from noble gas isotope systematics by Day, James M.D., Jones, Tim D., Nicklas, Robert W.

“…Noble gas isotope systematics, particular those of He, have been fundamental in showing that some ocean island basalts (OIB) were sourced from deep mantle…”
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Development of a novel mammalian display system for selection of antibodies against membrane proteins by Robertson, Nathan, Lopez-Anton, Nancy, Gurjar, Shalom A., Khalique, Hena, Khalaf, Zainab, Clerkin, Siobhan, Leydon, Vaughan R., Parker-Manuel, Richard, Raeside, Alexander, Payne, Tom, Jones, Tim D., Seymour, Len, Cawood, Ryan

“…Reliable, specific polyclonal and monoclonal antibodies are important tools in research and medicine. However, the discovery of antibodies against their…”
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Role of rainstorm intensity underestimated by data-derived flood models: Emerging global evidence from subsurface-dominated watersheds by Chappell, Nick A., Jones, Tim D., Tych, Wlodek, Krishnaswamy, Jagdish

“…Intense rainstorms are a prevalent feature of current weather. Evidence is presented showing that simulation of flood hydrographs shown to be dominated by…”
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Prediction of Immunogenicity of Therapeutic Proteins: Validity of Computational Tools by Bryson, Christine J., Jones, Tim D., Baker, Matthew P.

“…Most protein therapeutics have the potential to induce undesirable immune responses in patients. Many patients develop anti-therapeutic antibodies, which can…”
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A deimmunised form of the ribotoxin, α-sarcin, lacking CD4+ T cell epitopes and its use as an immunotoxin warhead by Jones, Tim D., Hearn, Arron R., Holgate, Robert G.E., Kozub, Dorota, Fogg, Mark H., Carr, Francis J., Baker, Matthew P., Lacadena, Javier, Gehlsen, Kurt R.

“…Abstract Fungal ribotoxins that block protein synthesis can be useful warheads in the context of a targeted immunotoxin. α-Sarcin is a small (17 kDa) fungal…”
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The INNs and outs of antibody nonproprietary names by Jones, Tim D., Carter, Paul J., Plückthun, Andreas, Vásquez, Max, Holgate, Robert G.E., Hötzel, Isidro, Popplewell, Andrew G., Parren, Paul W.H.I., Enzelberger, Markus, Rademaker, Hendrik J., Clark, Michael R., Lowe, David C., Dahiyat, Bassil I., Smith, Victoria, Lambert, John M., Wu, Herren, Reilly, Mary, Haurum, John S., Dübel, Stefan, Huston, James S., Schirrmann, Thomas, Janssen, Richard A.J., Steegmaier, Martin, Gross, Jane A., Bradbury, Andrew R.M., Burton, Dennis R., Dimitrov, Dimiter S., Chester, Kerry A., Glennie, Martin J., Davies, Julian, Walker, Adam, Martin, Steve, McCafferty, John, Baker, Matthew P.

“…An important step in drug development is the assignment of an International Nonproprietary Name (INN) by the World Health Organization (WHO) that provides…”
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Deimmunization of monoclonal antibodies by Jones, Tim D, Crompton, Laura J, Carr, Frank J, Baker, Matthew P

“…Immunogenicity is a major limitation to therapy with certain monoclonal antibodies and proteins. A major driver for immunogenicity is the presence of human…”
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A comparison of the ability of the human IgG1 allotypes G1m3 and G1m1,17 to stimulate T-cell responses from allotype matched and mismatched donors by Webster, Carl I, Bryson, Christine J, Cloake, Edward A, Jones, Tim D, Austin, Mark J, Karle, Anette C, Spindeldreher, Sebastian, Lowe, David C, Baker, Matthew P

“…The immunogenicity of clinically administered antibodies has clinical implications for the patients receiving them, ranging from mild consequences, such as…”
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An active contour model for measuring the area of leg ulcers by Jones, T.D., Plassmann, P.

“…Leg ulcers are chronic skin a wounds that affect many people and take a long time to heal. The progress of wound healing and the effect of clinical treatments…”
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A region of the C-terminal tail of the gp41 envelope glycoprotein of human immunodeficiency virus type 1 contains a neutralizing epitope: evidence for its exposure on the surface of the virion by Cleveland, S. Matthew, McLain, Lesley, Cheung, Linda, Jones, Tim D, Hollier, Mark, Dimmock, Nigel J

“…1 Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, UK 2 Axis Genetics, Babraham, Cambridge CB2 4AZ, UK Correspondence Nigel Dimmock…”
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Inactivated recombinant plant virus protects dogs from a lethal challenge with canine parvovirus by Langeveld, Jan P.M, Brennan, Frank R, Martı́nez-Torrecuadrada, Jorge L, Jones, Tim D, Boshuizen, Ronald S, Vela, Carmen, Casal, J.Ignacio, Kamstrup, Søren, Dalsgaard, Kristian, Meloen, Rob H, Bendig, Mary M, Hamilton, William D.O

“…A vaccine based upon a recombinant plant virus (CPMV-PARVO1), displaying a peptide derived from the VP2 capsid protein of canine parvovirus (CPV), has…”
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Targets of commitment in service provider-consumer relationships: a prototyping study by Jones, Tim D, Taylor, Shirley F, Bansal, Harvir S

“…Purpose - The purpose of this paper is to explore the question of whether or not there are three distinct targets of commitment in consumers' relationships…”
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Chimeric Plant Virus Particles Administered Nasally or Orally Induce Systemic and Mucosal Immune Responses in Mice by Brennan, F R, Bellaby, T, Helliwell, S M, Jones, T D, Kamstrup, S, Dalsgaard, K, Flock, J I, Hamilton, W D

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Analysis of the ability of five adjuvants to enhance immune responses to a chimeric plant virus displaying an HIV-1 peptide by McInerney, Tracey L, Brennan, Frank R, Jones, Tim D, Dimmock, Nigel J

“…The ability of five different adjuvants (alum, complete Freund's adjuvant, Quil A, AdjuPrime and Ribi) to stimulate humoral and T-cell mediated immune…”
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Properties of a neutralizing antibody that recognizes a conformational form of epitope ERDRD in the gp41 C-terminal tail of human immunodeficiency virus type 1 by Cleveland, S. Matthew, Jones, Tim D, Dimmock, Nigel J

“…Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, UK 1 Axis Genetics plc, Babraham, Cambridge CB2 4AZ, UK 2 Author for…”
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The concurrent emergence and causes of double volcanic hotspot tracks on the Pacific plate by Jones, T. D., Davies, D. R., Campbell, I. H., Iaffaldano, G., Yaxley, G., Kramer, S. C., Wilson, C. R.

“…The emergence of geographically and geochemically distinct double volcanic chains on the Pacific plate coincides with a recent azimuthal change in the motion…”
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Development of a novel mammalian display system for selection of antibodies against membrane proteins by Robertson, Nathan, Lopez-Anton, Nancy, Gurjar, Shalom A, Khalique, Hena, Khalaf, Zainab, Clerkin, Siobhan, Leydon, Vaughan R, Parker-Manuel, Richard, Raeside, Alexander, Payne, Tom, Jones, Tim D, Seymour, Len, Cawood, Ryan

“…Reliable, specific polyclonal and monoclonal antibodies are important tools in research and medicine. However, the discovery of antibodies against their…”
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Targets of commitment in service providerconsumer relationships a prototyping study by Jones, Tim D., Taylor, Shirley F., Bansal, Harvir S.

“…Purpose The purpose of this paper is to explore the question of whether or not there are three distinct targets of commitment in consumers' relationships with…”
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Plant-derived vaccine protects target animals against a viral disease by Dalsgaard, K. (Danish Veterinary Institute for Virus Research, Kalvehave, Denmark.), Uttenthal, A, Jones, T.D, Xu, F, Merryweather, A, Hamilton, W.D.O, Langeveld, J.P.M, Boshuizen, R.S, Kamstrup, S, Lomonossoff, G.P

“…The successful expression of animal or human virus epitopes on the surface of plant viruses has recently been demonstrated. These chimeric virus particles…”
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