Search Results - "Jones, Sunny J"

A CRISPR/Cas9-Engineered ARID1A -Deficient Human Gastric Cancer Organoid Model Reveals Essential and Nonessential Modes of Oncogenic Transformation by Lo, Yuan-Hung, Kolahi, Kevin S, Du, Yuhong, Chang, Chiung-Ying, Krokhotin, Andrey, Nair, Ajay, Sobba, Walter D, Karlsson, Kasper, Jones, Sunny J, Longacre, Teri A, Mah, Amanda T, Tercan, Bahar, Sockell, Alexandra, Xu, Hang, Seoane, Jose A, Chen, Jin, Shmulevich, Ilya, Weissman, Jonathan S, Curtis, Christina, Califano, Andrea, Fu, Haian, Crabtree, Gerald R, Kuo, Calvin J

“…Mutations in rank among the most common molecular aberrations in human cancer. However, oncogenic consequences of mutation in human cells remain poorly defined…”
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Conformational Dynamics of Calcium-Triggered Activation of Fusion by Synaptotagmin by Krishnakumar, Shyam S., Kümmel, Daniel, Jones, Sunny J., Radoff, Daniel T., Reinisch, Karin M., Rothman, James E.

“…Synaptotagmin triggers rapid exocytosis of neurotransmitters from synaptic vesicles in response to Calcium (Ca2+) ions. Here, we use a novel Nanodisc-based…”
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A modular master regulator landscape controls cancer transcriptional identity by Paull, Evan O., Aytes, Alvaro, Jones, Sunny J., Subramaniam, Prem S., Giorgi, Federico M., Douglass, Eugene F., Tagore, Somnath, Chu, Brennan, Vasciaveo, Alessandro, Zheng, Siyuan, Verhaak, Roel, Abate-Shen, Cory, Alvarez, Mariano J., Califano, Andrea

“…Despite considerable efforts, the mechanisms linking genomic alterations to the transcriptional identity of cancer cells remain elusive. Integrative genomic…”
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Oncoprotein-specific molecular interaction maps (SigMaps) for cancer network analyses by Broyde, Joshua, Simpson, David R., Murray, Diana, Paull, Evan O., Chu, Brennan W., Tagore, Somnath, Jones, Sunny J., Griffin, Aaron T., Giorgi, Federico M., Lachmann, Alexander, Jackson, Peter, Sweet-Cordero, E. Alejandro, Honig, Barry, Califano, Andrea

“…Tumor-specific elucidation of physical and functional oncoprotein interactions could improve tumorigenic mechanism characterization and therapeutic response…”
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Abstract 123: A CRISPR/Cas9-engineered ARID1A-deficient human gastric cancer organoid model reveals essential and non-essential modes of oncogenic transformation by Lo, Yuan-Hung, Kolahi, Kevin S., Du, Yuhong, Chang, Chiung-Ying, Krokhotin, Andrey, Nair, Ajay, Sobba, Walter D., Karlsson, Kasper, Jones, Sunny J., Longacre, Teri A., Mah, Amanda T., Sockell, Alexandra, Seoane, Jose A., Chen, Jin, Weissman, Jonathan S., Curtis, Christina, Califano, Andrea, Fu, Haian, Crabtree, Gerald R., Kuo, Calvin J.

“…Abstract Mutations in ARID1A, encoding a subunit of the BAF chromatin remodeling complex, rank amongst the most common molecular aberrations in human cancer…”
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