Search Results - "Jones, Roger A."

Cyclic [G(2′,5′)pA(3′,5′)p] Is the Metazoan Second Messenger Produced by DNA-Activated Cyclic GMP-AMP Synthase by Gao, Pu, Ascano, Manuel, Wu, Yang, Barchet, Winfried, Gaffney, Barbara L., Zillinger, Thomas, Serganov, Artem A., Liu, Yizhou, Jones, Roger A., Hartmann, Gunther, Tuschl, Thomas, Patel, Dinshaw J.

“…Recent studies identified cyclic GMP-AMP (cGAMP) as a metazoan second messenger triggering an interferon response. cGAMP is generated from GTP and ATP by…”
Get full text

Structure-Function Analysis of STING Activation by c[G(2′,5′)pA(3′,5′)p] and Targeting by Antiviral DMXAA by Gao, Pu, Ascano, Manuel, Zillinger, Thomas, Wang, Weiyi, Dai, Peihong, Serganov, Artem A., Gaffney, Barbara L., Shuman, Stewart, Jones, Roger A., Deng, Liang, Hartmann, Gunther, Barchet, Winfried, Tuschl, Thomas, Patel, Dinshaw J.

“…Binding of dsDNA by cyclic GMP-AMP (cGAMP) synthase (cGAS) triggers formation of the metazoan second messenger c[G(2′,5′)pA(3′,5′)p], which binds the signaling…”
Get full text

Global Plant Virus Disease Pandemics and Epidemics by Jones, Roger A C

“…The world's staple food crops, and other food crops that optimize human nutrition, suffer from global virus disease pandemics and epidemics that greatly…”
Get full text

Disease Pandemics and Major Epidemics Arising from New Encounters between Indigenous Viruses and Introduced Crops by Jones, Roger A C

“…Virus disease pandemics and epidemics that occur in the world's staple food crops pose a major threat to global food security, especially in developing…”
Get full text

Australian Cool-Season Pulse Seed-Borne Virus Research: 1. Alfalfa and Cucumber Mosaic Viruses and Less Important Viruses by Jones, Roger A C, Congdon, Benjamin S

“…Here, we review the research undertaken since the 1950s in Australia's grain cropping regions on seed-borne virus diseases of cool-season pulses caused by…”
Get full text

Molecular Analysis of the Global Population of Potato Virus S Redefines Its Phylogeny, and Has Crop Biosecurity Implications by Topkaya, Şerife, Çelik, Ali, Santosa, Adyatma Irawan, Jones, Roger A C

“…In 2020, 264 samples were collected from potato fields in the Turkish provinces of Bolu, Afyon, Kayseri and Niğde. RT-PCR tests, with primers which amplified…”
Get full text

Plant virology and next generation sequencing: experiences with a Potyvirus by Kehoe, Monica A, Coutts, Brenda A, Buirchell, Bevan J, Jones, Roger A C

“…Next generation sequencing is quickly emerging as the go-to tool for plant virologists when sequencing whole virus genomes, and undertaking plant metagenomic…”
Get full text

Structure of the intramolecular human telomeric G-quadruplex in potassium solution: a novel adenine triple formation by Dai, Jixun, Punchihewa, Chandanamali, Ambrus, Attila, Chen, Ding, Jones, Roger A, Yang, Danzhou

“…We report the NMR solution structure of the intramolecular G-quadruplex formed in human telomeric DNA in K⁺. The hybrid-type telomeric G-quadruplex consists of…”
Get full text

A proposal to rationalize within-species plant virus nomenclature: benefits and implications of inaction by Jones, Roger A. C., Kehoe, Monica A.

“…Current approaches used to name within-species, plant virus phylogenetic groups are often misleading and illogical. They involve names based on biological…”
Get full text

Solution Structure of the Biologically Relevant G-Quadruplex Element in the Human c-MYC Promoter. Implications for G-Quadruplex Stabilization by Ambrus, Attila, Chen, Ding, Dai, Jixun, Jones, Roger A., Yang, Danzhou

“…The nuclease hypersensitivity element III1 (NHE III1) of the c-MYC promoter strongly controls the transcriptional activity of the c-MYC oncogene. The…”
Get full text

NMR solution structure of the major G-quadruplex structure formed in the human BCL2 promoter region by Dai, Jixun, Chen, Ding, Jones, Roger A, Hurley, Laurence H, Yang, Danzhou

“…BCL2 protein functions as an inhibitor of cell apoptosis and has been found to be aberrantly expressed in a wide range of human diseases. A highly GC-rich…”
Get full text

Host Resistance to Virus Diseases Provides a Key Enabler towards Fast Tracking Gains in Grain Lupin Breeding by Jones, Roger A C

“…Four lupin species, , , , and , are grown as cool-season grain legume crops. Fifteen viruses infect them. Two of these, bean yellow mosaic virus (BYMV) and…”
Get full text

Aminoglycoside antibiotics induce bacterial biofilm formation by Miller, Samuel I, Hoffman, Lucas R, D'Argenio, David A, MacCoss, Michael J, Zhang, Zhaoying, Jones, Roger A

“…Biofilms are adherent aggregates of bacterial cells that form on biotic and abiotic surfaces, including human tissues. Biofilms resist antibiotic treatment and…”
Get full text

Genomic High Plains Wheat Mosaic Virus Sequences from Australia: Their Phylogenetics and Evidence for Emaravirus Recombination and Reassortment by Jones, Roger A C, Vazquez-Iglesias, Ines, McGreig, Sam, Fox, Adrian, Gibbs, Adrian J

“…High Plains wheat mosaic virus (HPWMoV) causes a serious disease in major wheat-growing regions worldwide. We report here the complete or partial genomic…”
Get full text

Structural Basis for Molecular Discrimination by a 3′,3′-cGAMP Sensing Riboswitch by Ren, Aiming, Wang, Xin C., Kellenberger, Colleen A., Rajashankar, Kanagalaghatta R., Jones, Roger A., Hammond, Ming C., Patel, Dinshaw J.

“…Cyclic dinucleotides are second messengers that target the adaptor STING and stimulate the innate immune response in mammals. Besides protein receptors, there…”
Get full text

Effects of introduced and indigenous viruses on native plants: exploring their disease causing potential at the agro-ecological interface by Vincent, Stuart J, Coutts, Brenda A, Jones, Roger A C

“…The ever increasing movement of viruses around the world poses a major threat to plants growing in cultivated and natural ecosystems. Both generalist and…”
Get full text

Split personality of a Potyvirus: to specialize or not to specialize? by Kehoe, Monica A, Coutts, Brenda A, Buirchell, Bevan J, Jones, Roger A C

“…Bean yellow mosaic virus (BYMV), genus Potyvirus, has an extensive natural host range encompassing both dicots and monocots. Its phylogenetic groups were…”
Get full text

Historical virus isolate collections: An invaluable resource connecting plant virology’s pre‐sequencing and post‐sequencing eras by Jones, Roger A. C., Boonham, Neil, Adams, Ian P., Fox, Adrian

“…Many laboratories maintain historical collections of preserved plant virus isolates that store a wealth of untapped data, including original type isolates,…”
Get full text

Virus Diseases of Cereal and Oilseed Crops in Australia: Current Position and Future Challenges by Jones, Roger A C, Sharman, Murray, Trębicki, Piotr, Maina, Solomon, Congdon, Benjamin S

“…This review summarizes research on virus diseases of cereals and oilseeds in Australia since the 1950s. All viruses known to infect the diverse range of cereal…”
Get full text

Indigenous and introduced potyviruses of legumes and Passiflora spp. from Australia: biological properties and comparison of coat protein nucleotide sequences by Coutts, Brenda A., Kehoe, Monica A., Webster, Craig G., Wylie, Stephen J., Jones, Roger A. C.

“…Five Australian potyviruses, passion fruit woodiness virus (PWV), passiflora mosaic virus (PaMV), passiflora virus Y, clitoria chlorosis virus (ClCV) and…”
Get full text