Search Results - "Jones, Robert M"

GPR41/FFAR3 and GPR43/FFAR2 as Cosensors for Short-Chain Fatty Acids in Enteroendocrine Cells vs FFAR3 in Enteric Neurons and FFAR2 in Enteric Leukocytes by Nøhr, Mark K, Pedersen, Maria H, Gille, Andreas, Egerod, Kristoffer L, Engelstoft, Maja S, Husted, Anna Sofie, Sichlau, Rasmus M, Grunddal, Kaare V, Seier Poulsen, Steen, Han, Sangdon, Jones, Robert M, Offermanns, Stefan, Schwartz, Thue W

“…The expression of short-chain fatty acid receptors GPR41/FFAR3 and GPR43/ free fatty acid receptor 2 (FFAR2) was studied in the gastrointestinal tract of…”
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Exploring AuRh Nanoalloys: A Computational Perspective on the Formation and Physical Properties by Vanzan, Mirko, Jones, Robert M., Corni, Stefano, D'Agosta, Roberto, Baletto, Francesca

“…We studied the formation of AuRh nanoalloys (between 20–150 atoms) in the gas phase by means of Molecular Dynamics (MD) calculations, exploring three possible…”
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C–H activation reactions as useful tools for medicinal chemists by Caro-Diaz, Eduardo J.E., Urbano, Mariangela, Buzard, Daniel J., Jones, Robert M.

“…[Display omitted] In recent years, there has been an exponential rise in the number of reports describing synthetic methods that utilize catalytic sp3 and sp2…”
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A systematic review of small for size syndrome after major hepatectomy and liver transplantation by Riddiough, Georgina E., Christophi, Christopher, Jones, Robert M., Muralidharan, Vijayaragavan, Perini, Marcos V.

“…Major hepatectomy (MH) and particular types of liver transplantation (LT) (reduced size graft, living-donor and split-liver transplantation) lead to a…”
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The role of changing temperature in microbial metabolic processes during permafrost thaw by Messan, Komi S, Jones, Robert M, Doherty, Stacey J, Foley, Karen, Douglas, Thomas A, Barbato, Robyn A

“…Approximately one fourth of the Earth's Northern Hemisphere is underlain by permafrost, earth materials (soil, organic matter, or bedrock), that has been…”
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A Role for Intestinal Endocrine Cell-Expressed G Protein-Coupled Receptor 119 in Glycemic Control by Enhancing Glucagon-Like Peptide-1 and Glucose-Dependent Insulinotropic Peptide Release by Chu, Zhi-Liang, Carroll, Chris, Alfonso, Jean, Gutierrez, Veronica, He, Hongmei, Lucman, Annette, Pedraza, Melinda, Mondala, Helen, Gao, Hui, Bagnol, Didier, Chen, Ruoping, Jones, Robert M, Behan, Dominic P, Leonard, James

“…We recently showed that activation of G protein-coupled receptor 119 (GPR119) (also termed glucose dependent insulinotropic receptor) improves glucose…”
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Illuminating structural proteins in viral “dark matter” with metaproteomics by Brum, Jennifer R., Ignacio-Espinoza, J. Cesar, Kim, Eun-Hae, Trubl, Gareth, Jones, Robert M., Roux, Simon, VerBerkmoes, Nathan C., Rich, Virginia I., Sullivan, Matthew B.

“…Viruses are ecologically important, yet environmental virology is limited by dominance of unannotated genomic sequences representing taxonomic and functional…”
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Reading the ground: Understanding the response of bioelectric microbes to anthropogenic compounds in soil based terrestrial microbial fuel cells by Barbato, Robyn A, Jones, Robert M, Musty, Michael A, Slone, Scott M

“…Electrogenic bacteria produce power in soil based terrestrial microbial fuel cells (tMFCs) by growing on electrodes and transferring electrons released from…”
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GPR119 agonists for the treatment of type 2 diabetes by Jones, Robert M, Leonard, James N, Buzard, Daniel J, Lehmann, Juerg

“…Diabetes is a chronic disease that occurs when the pancreas does not produce enough insulin, or when the body cannot effectively use the insulin it produces…”
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Keanu: a novel visualization tool to explore biodiversity in metagenomes by Thrash, Adam, Arick, 2nd, Mark, Barbato, Robyn A, Jones, Robert M, Douglas, Thomas A, Esdale, Julie, Perkins, Edward J, Garcia-Reyero, Natàlia

“…One of the main challenges when analyzing complex metagenomics data is the fact that large amounts of information need to be presented in a comprehensive and…”
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A Heterodimer-Selective Agonist Shows in vivo Relevance of G Protein-Coupled Receptor Dimers by Waldhoer, Maria, Fong, Jamie, Jones, Robert M., Lunzer, Mary M., Sharma, Shiv K., Kostenis, Evi, Portoghese, Philip S., Whistler, Jennifer L., Lifton, Richard P.

“…There has been much speculation regarding the functional relevance of G protein-coupled receptor heterodimers, primarily because demonstrating their existence…”
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Discovery of the First Potent and Orally Efficacious Agonist of the Orphan G-Protein Coupled Receptor 119 by Semple, Graeme, Fioravanti, Beatriz, Pereira, Guillherme, Calderon, Imelda, Uy, Jane, Choi, Karoline, Xiong, Yifeng, Ren, Albert, Morgan, Michael, Dave, Vibha, Thomsen, William, Unett, David J, Xing, Charles, Bossie, Stuart, Carroll, Chris, Chu, Zhi-Liang, Grottick, Andrew J, Hauser, Erin K, Leonard, James, Jones, Robert M

“…GPR119 is a rhodopsin-like GPCR expressed in pancreatic β-cells and incretin releasing cells in the GI tract. As with incretins, GPR119 increases cAMP levels…”
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Discovery of a Hydroxylamine-Based Brain-Penetrant EGFR Inhibitor for Metastatic Non-Small-Cell Lung Cancer by Hill, Jarvis, Jones, Robert M, Crich, David

“…Metastases to the brain remain a significant problem in lung cancer, as treatment by most small-molecule targeted therapies is severely limited by efflux…”
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Discovery of APD371: Identification of a Highly Potent and Selective CB2 Agonist for the Treatment of Chronic Pain by Han, Sangdon, Thoresen, Lars, Jung, Jae-Kyu, Zhu, Xiuwen, Thatte, Jayant, Solomon, Michelle, Gaidarov, Ibragim, Unett, David J, Yoon, Woo Hyun, Barden, Jeremy, Sadeque, Abu, Usmani, Amin, Chen, Chuan, Semple, Graeme, Grottick, Andrew J, Al-Shamma, Hussein, Christopher, Ronald, Jones, Robert M

“…The discovery of a novel, selective and fully efficacious CB2 agonist with satisfactory pharmacokinetic and pharmaceutical properties is described. Compound 6…”
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Outcomes of cholecystectomy for treatment of acute cholecystitis in octogenarians by Nikfarjam, Mehrdad, Yeo, David, Perini, Marcos, Fink, Michael A., Muralidharan, Vijayaragavan, Starkey, Graham, Jones, Robert M., Christophi, Christopher

“…Background The independent influence of advanced age on outcomes in contemporary series treated by early cholecystectomy is undetermined. Methods Elderly…”
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Complementary Asymmetric Routes to (R)‑2-(7-Hydroxy-2,3-dihydro‑1H‑pyrrolo[1,2‑a]indol-1-yl)acetate by Schrader, Thomas O, Johnson, Benjamin R, Lopez, Luis, Kasem, Michelle, Gharbaoui, Tawfik, Sengupta, Dipanjan, Buzard, Daniel, Basmadjian, Christine, Jones, Robert M

“…Two distinct and scalable enantioselective approaches to the tricyclic indole (R)-2-(7-hydroxy-2,3-dihydro-1H-pyrrolo[1,2-a]indol-1-yl)acetate, an important…”
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Efficacy and safety of repeated perioperative doses of recombinant factor VIIa in liver transplantation by Lodge, J. Peter A., Jonas, Sven, Jones, Robert M., Olausson, Michael, Mir‐Pallardo, José, Soefelt, Soeren, Garcia‐Valdecasas, Juan Carlos, McAlister, Vivian, Mirza, Darius F.

“…Patients undergoing orthotopic liver transplantation (OLT) have excessive blood loss during surgery that requires blood transfusions, leading to increased…”
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Intestinal transplantation: Current status and future directions by Garg, Mayur, Jones, Robert M, Vaughan, Rhys B, Testro, Adam G

“…Three decades after the first intestinal transplant was performed in humans, this life‐saving procedure has come of age and now offers hope of long‐term…”
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Inferior Vena Cava Resection and Hemihepatectomy for Leiomyosarcoma, Utilizing Cardiopulmonary Bypass, in Situ Hepatic Perfusion, and Distal Hypothermic Circulatory Arrest by Miles, Lachlan F., MBBS, Hu, Raymond, MBBS, FANZCA, Jones, Robert M., MBChB, FRACS, Carson, Scott, CCP, McCall, Peter R., MBBS, FANZCA

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Outcomes of contemporary management of gangrenous and non-gangrenous acute cholecystitis by Nikfarjam, Mehrdad, Niumsawatt, Vachara, Sethu, Arun, Fink, Michael A, Muralidharan, Vijayaragavan, Starkey, Graham, Jones, Robert M, Christophi, Christopher

“…Abstract Background Gangrenous cholecystitis (GC) is considered a more severe form of acute cholecystitis. The risk factors associated with this condition and…”
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