Search Results - "Jones, Robert C."
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Cerebellar nuclei evolved by repeatedly duplicating a conserved cell-type set
Published in Science (American Association for the Advancement of Science) (18-12-2020)“…How have complex brains evolved from simple circuits? Here we investigated brain region evolution at cell-type resolution in the cerebellar nuclei, the output…”
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2
Habitat value of bivalve shellfish and seaweed aquaculture for fish and invertebrates: Pathways, synthesis and next steps
Published in Reviews in aquaculture (01-01-2022)“…Aquaculture can have negative environmental impacts, adding to the suite of anthropogenic stressors that challenge coastal ecosystems. However, a growing body…”
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A global spatial analysis reveals where marine aquaculture can benefit nature and people
Published in PloS one (09-10-2019)“…Aquaculture of bivalve shellfish and seaweed represents a global opportunity to simultaneously advance coastal ecosystem recovery and provide substantive…”
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High throughput gene expression measurement with real time PCR in a microfluidic dynamic array
Published in PloS one (27-02-2008)“…We describe a high throughput gene expression platform based on microfluidic dynamic arrays. This system allows 2,304 simultaneous real time PCR gene…”
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5
Aging Fly Cell Atlas identifies exhaustive aging features at cellular resolution
Published in Science (American Association for the Advancement of Science) (16-06-2023)“…Aging is characterized by a decline in tissue function, but the underlying changes at cellular resolution across the organism remain unclear. Here, we present…”
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Diverse homeostatic and immunomodulatory roles of immune cells in the developing mouse lung at single cell resolution
Published in eLife (02-06-2020)“…At birth, the lungs rapidly transition from a pathogen-free, hypoxic environment to a pathogen-rich, rhythmically distended air-liquid interface. Although many…”
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Miniaturised interaction proteomics on a microfluidic platform with ultra-low input requirements
Published in Nature communications (04-04-2019)“…Essentially all cellular processes are orchestrated by protein-protein interactions (PPIs). In recent years, affinity purification coupled to mass spectrometry…”
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Single-cell transcriptomes of developing and adult olfactory receptor neurons in Drosophila
Published in eLife (08-02-2021)“…Recognition of environmental cues is essential for the survival of all organisms. Transcriptional changes occur to enable the generation and function of the…”
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Hyperoxia prevents the dynamic neonatal increases in lung mesenchymal cell diversity
Published in Scientific reports (23-01-2024)“…Rapid expansion of the pulmonary microvasculature through angiogenesis drives alveolarization, the final stage of lung development that occurs postnatally and…”
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10
Taking qPCR to a higher level: Analysis of CNV reveals the power of high throughput qPCR to enhance quantitative resolution
Published in Methods (San Diego, Calif.) (01-04-2010)“…This paper assesses the quantitative resolution of qPCR using copy number variation (CNV) as a paradigm. An error model is developed for real-time qPCR data…”
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Coronary blood vessels from distinct origins converge to equivalent states during mouse and human development
Published in eLife (15-12-2021)“…Most cell fate trajectories during development follow a diverging, tree-like branching pattern, but the opposite can occur when distinct progenitors contribute…”
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Temporal evolution of single-cell transcriptomes of Drosophila olfactory projection neurons
Published in eLife (11-01-2021)“…Neurons undergo substantial morphological and functional changes during development to form precise synaptic connections and acquire specific physiological…”
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13
"So, to Recap…"
Published in Anesthesiology (Philadelphia) (01-06-2024)Get full text
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14
High-throughput single nucleotide polymorphism genotyping using nanofluidic Dynamic Arrays
Published in BMC genomics (28-11-2009)“…Single nucleotide polymorphisms (SNPs) have emerged as the genetic marker of choice for mapping disease loci and candidate gene association studies, because of…”
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15
Multiplexed Analysis of Protein–Ligand Interactions by Fluorescence Anisotropy in a Microfluidic Platform
Published in Analytical chemistry (Washington) (07-10-2014)“…Homogeneous assay platforms for measuring protein–ligand interactions are highly valued due to their potential for high-throughput screening. However, the…”
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Inhibiting USP16 rescues stem cell aging and memory in an Alzheimer's model
Published in eLife (21-03-2022)“…Alzheimer's disease (AD) is a progressive neurodegenerative disease observed with aging that represents the most common form of dementia. To date, therapies…”
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Global principles for restorative aquaculture to foster aquaculture practices that benefit the environment
Published in Conservation science and practice (01-08-2023)“…The magnitude of negative environmental impacts generated by food production means it is now imperative we develop food systems in a way that can actively…”
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Developmental diversity and unique sensitivity to injury of lung endothelial subtypes during postnatal growth
Published in iScience (17-03-2023)“…At birth, the lung is still immature, heightening susceptibility to injury but enhancing regenerative capacity. Angiogenesis drives postnatal lung development…”
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A microfluidic device for preparing next generation DNA sequencing libraries and for automating other laboratory protocols that require one or more column chromatography steps
Published in PloS one (24-07-2013)“…Library preparation for next-generation DNA sequencing (NGS) remains a key bottleneck in the sequencing process which can be relieved through improved…”
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20
Machine Learning for Stock Selection
Published in Financial analysts journal (01-07-2019)“…Machine learning is an increasingly important and controversial topic in quantitative finance. A lively debate persists as to whether machine learning…”
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