Search Results - "Jones, Richard B."

Systematic Discovery of TLR Signaling Components Delineates Viral-Sensing Circuits by Chevrier, Nicolas, Mertins, Philipp, Artyomov, Maxim N., Shalek, Alex K., Iannacone, Matteo, Ciaccio, Mark F., Gat-Viks, Irit, Tonti, Elena, DeGrace, Marciela M., Clauser, Karl R., Garber, Manuel, Eisenhaure, Thomas M., Yosef, Nir, Robinson, Jacob, Sutton, Amy, Andersen, Mette S., Root, David E., von Andrian, Ulrich, Jones, Richard B., Park, Hongkun, Carr, Steven A., Regev, Aviv, Amit, Ido, Hacohen, Nir

“…Deciphering the signaling networks that underlie normal and disease processes remains a major challenge. Here, we report the discovery of signaling components…”
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A quantitative protein interaction network for the ErbB receptors using protein microarrays by MacBeath, Gavin, Jones, Richard B, Gordus, Andrew, Krall, Jordan A

“…Although epidermal growth factor receptor (EGFR; also called ErbB1) and its relatives initiate one of the most well-studied signalling networks, there is not…”
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Reverse total shoulder arthroplasty with structural bone grafting of large glenoid defects by Jones, Richard B., MD, Wright, Thomas W., MD, Zuckerman, Joseph D., MD

“…Background Large glenoid defects pose difficulties in shoulder arthroplasty. Structural grafts consisting of a humeral head autograft, iliac crest, and…”
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A potent and highly specific FN3 monobody inhibitor of the Abl SH2 domain by Wojcik, John, Hantschel, Oliver, Grebien, Florian, Kaupe, Ines, Bennett, Keiryn L, Barkinge, John, Jones, Richard B, Koide, Akiko, Superti-Furga, Giulio, Koide, Shohei

“…SH2 domains are present in many proteins, and designing specific inhibitors has been a challenge. Now a monobody, based on a fibronectin type III domain…”
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Inhibition of HIV Replication by Apolipoprotein A-I Binding Protein Targeting the Lipid Rafts by Dubrovsky, Larisa, Ward, Adam, Choi, Soo-Ho, Pushkarsky, Tatiana, Brichacek, Beda, Vanpouille, Christophe, Adzhubei, Alexei A, Mukhamedova, Nigora, Sviridov, Dmitri, Margolis, Leonid, Jones, Richard B, Miller, Yury I, Bukrinsky, Michael

“…Apolipoprotein A-I binding protein (AIBP) is a protein involved in regulation of lipid rafts and cholesterol efflux. AIBP has been suggested to function as a…”
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Comprehensive binary interaction mapping of SH2 domains via fluorescence polarization reveals novel functional diversification of ErbB receptors by Hause, Jr, Ronald J, Leung, Kin K, Barkinge, John L, Ciaccio, Mark F, Chuu, Chih-Pin, Jones, Richard B

“…First-generation interaction maps of Src homology 2 (SH2) domains with receptor tyrosine kinase (RTK) phosphosites have previously been generated using protein…”
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Erratum for Dubrovsky et al., "Inhibition of HIV Replication by Apolipoprotein A-I Binding Protein Targeting the Lipid Rafts" by Dubrovsky, Larisa, Ward, Adam, Choi, Soo-Ho, Pushkarsky, Tatiana, Brichacek, Beda, Vanpouille, Christophe, Adzhubei, Alexei A, Mukhamedova, Nigora, Sviridov, Dmitri, Margolis, Leonid, Jones, Richard B, Miller, Yury I, Bukrinsky, Michael

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20% Chance of Rain: Exploring the Concept of Risk by Jones, Richard B

“…There are plenty of books on specialized risk topics but few that deal with the broad diversity and daily applicability of this subject. Risk applications…”
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20% Chance of Rain: Exploring the Concept of Risk by Richard B. Jones

“…There are plenty of books on specialized risk topics but few that deal with the broad diversity and daily applicability of this subject. Risk applications…”
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The Liability of Reliability by Jones, Richard B., Mason, Dwayne

“…Product development, maintenance, and operational risks are routinely assessed based on historical data and industry best practices. And the four major…”
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Systems-Level Analysis of ErbB4 Signaling in Breast Cancer: A Laboratory to Clinical Perspective by Chuu, Chih-Pin, Chen, Rou-Yu, Barkinge, John L, Ciaccio, Mark F, Jones, Richard B

“…Although expression of the ErbB4 receptor tyrosine kinase in breast cancer is generally regarded as a marker for favorable patient prognosis, controversial…”
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Effect of Tuberosity Healing on Clinical Outcomes in Elderly Patients Treated With a Reverse Shoulder Arthroplasty for 3- and 4-Part Proximal Humerus Fractures by Simovitch, Ryan W, Roche, Chris P, Jones, Richard B, Routman, Howard D, Marczuk, Yann, Wright, Thomas W, Zuckerman, Joseph D

“…OBJECTIVES:To evaluate tuberosity union rate and clinical outcome after 3- and 4-part proximal humerus fractures in the elderly. DESIGN:Retrospective,…”
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Systems analysis of EGF receptor signaling dynamics with microwestern arrays by Jones, Richard B, Ciaccio, Mark F, Wagner, Joel P, Chuu, Chih-Pin, Lauffenburger, Douglas A

“…Microwestern arrays combine the advantages of scalability of reverse phase protein arrays and the information content of western blotting for analyzing protein…”
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Innate immune and chemically triggered oxidative stress modifies translational fidelity by David, Alexandre, Goodenbour, Jeffrey M, Netzer, Nir, Boone, David, Dolan, Brian, Pan, Tao, Jones, Richard B, Yewdell, Jonathan W, Bennink, Jack R, Embry, Alan, Rosner, Marsha R, Gibbs, James S, Hickman, Heather D, Eves, Eva M, Berglund, Peter, Das, Suman, Dittmar, Kimberly A, Schneider, Jeffrey R

“…Translational fidelity, essential for protein and cell function, requires accurate transfer RNA (tRNA) aminoacylation. Purified aminoacyl-tRNA synthetases…”
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Two-year clinical outcomes and complication rates in anatomic and reverse shoulder arthroplasty implanted with Exactech GPS intraoperative navigation by Youderian, Ari R., Greene, Alexander T., Polakovic, Sandrine V., Davis, Noah Z., Parsons, Moby, Papandrea, Rick F., Jones, Richard B., Byram, Ian R., Gobbato, Bruno B., Wright, Thomas W., Flurin, Pierre-Henri, Zuckerman, Joseph D.

“…We compared the 2-year clinical outcomes of both anatomic and reverse total shoulder arthroplasty (ATSA and RTSA) using intraoperative navigation compared to…”
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T cells with high PD-1 expression are associated with lower HIV-specific immune responses despite long-term antiretroviral therapy by Macatangay, Bernard J.C., Gandhi, Rajesh T., Jones, Richard B., Mcmahon, Deborah K., Lalama, Christina M., Bosch, Ronald J., Cyktor, Joshua C., Thomas, Allison S., Borowski, Luann, Riddler, Sharon A., Hogg, Evelyn, Stevenson, Eva, Eron, Joseph J., Mellors, John W., Rinaldo, Charles R.

“…OBJECTIVE:We evaluated frequencies of T cells with high PD-1 expression (PD-1) before and after long-term effective antiretroviral therapy (ART), and…”
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SH2 Domains Recognize Contextual Peptide Sequence Information to Determine Selectivity by Liu, Bernard A., Jablonowski, Karl, Shah, Eshana E., Engelmann, Brett W., Jones, Richard B., Nash, Piers D.

“…Selective ligand recognition by modular protein interaction domains is a primary determinant of specificity in signaling pathways. Src homology 2 (SH2) domains…”
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Transcriptomic analysis of human endogenous retroviruses in systemic lupus erythematosus by Iñiguez, Luis P., de Mulder Rougvie, Miguel, Stearrett, Nathaniel, Jones, Richard B., Ormsby, Christopher E., Reyes-Terán, Gustavo, Crandall, Keith A., Nixon, Douglas F., Bendall, Matthew L.

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Microwestern Arrays for Systems-Level Analysis of SH2 Domain-Containing Proteins by Ciaccio, Mark F, Jones, Richard B

“…The Microwestern Array (MWA) method combines the scalability and miniaturization afforded by the Reverse Phase Lysate Array (RPLA) approach with the…”
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Mapping glucose-mediated gut-to-brain signalling pathways in humans by Little, Tanya J., McKie, Shane, Jones, Richard B., D'Amato, Massimo, Smith, Craig, Kiss, Orsolya, Thompson, David G., McLaughlin, John T.

“…Previous fMRI studies have demonstrated that glucose decreases the hypothalamic BOLD response in humans. However, the mechanisms underlying the CNS response to…”
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