Search Results - "Jones, Krysten L."

Expanded palette of RNA base editors for comprehensive RBP-RNA interactome studies by Medina-Munoz, Hugo C., Kofman, Eric, Jagannatha, Pratibha, Boyle, Evan A., Yu, Tao, Jones, Krysten L., Mueller, Jasmine R., Lykins, Grace D., Doudna, Andrew T., Park, Samuel S., Blue, Steven M., Ranzau, Brodie L., Kohli, Rahul M., Komor, Alexis C., Yeo, Gene W.

“…RNA binding proteins (RBPs) are key regulators of RNA processing and cellular function. Technologies to discover RNA targets of RBPs such as TRIBE (targets of…”
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An RNA-targeting CRISPR–Cas13d system alleviates disease-related phenotypes in Huntington’s disease models by Morelli, Kathryn H., Wu, Qian, Gosztyla, Maya L., Liu, Hongshuai, Yao, Minmin, Zhang, Chuangchuang, Chen, Jiaxu, Marina, Ryan J., Lee, Kari, Jones, Krysten L., Huang, Megan Y., Li, Allison, Smith-Geater, Charlene, Thompson, Leslie M., Duan, Wenzhen, Yeo, Gene W.

“…Huntington’s disease (HD) is a fatal, dominantly inherited neurodegenerative disorder caused by CAG trinucleotide expansion in exon 1 of the huntingtin ( HTT )…”
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MECP2-related pathways are dysregulated in a cortical organoid model of myotonic dystrophy by Morelli, Kathryn H, Jin, Wenhao, Shathe, Shashank, Madrigal, Assael A, Jones, Krysten L, Schwartz, Joshua L, Bridges, Tristan, Mueller, Jasmine R, Shankar, Archana, Chaim, Isaac A, Day, John W, Yeo, Gene W

“…Myotonic dystrophy type 1 (DM1) is a multisystem, autosomal-dominant inherited disorder caused by CTG microsatellite repeat expansions (MREs) in the 3'…”
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