Search Results - "Jones, Kris"

Keeping an "eye" on the experiment: computer vision for real-time monitoring and control by El-khawaldeh, Rama, Guy, Mason, Bork, Finn, Taherimakhsousi, Nina, Jones, Kris N, Hawkins, Joel M, Han, Lu, Pritchard, Robert P, Cole, Blaine A, Monfette, Sebastien, Hein, Jason E

“…This work presents a generalizable computer vision (CV) and machine learning model that is used for automated real-time monitoring and control of a diverse…”
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Application of Biocatalytic Reductive Amination for the Synthesis of a Key Intermediate to a CDK 2/4/6 Inhibitor by Duan, Shengquan, Widlicka, Daniel W, Burns, Michael P, Kumar, Rajesh, Hotham, Ian, Desrosiers, Jean-Nicolas, Bowles, Paul, Jones, Kris N, Nicholson, Lindsay D, Buetti-Weekly, Michele T, Han, Lu, Steflik, Jeremy, Hansen, Eric, Hayward, Cheryl M, Strohmeyer, Holly, Monfette, Sébastien, Sutton, Scott C, Morris, Christopher

“…Biocatalytic reductive amination catalyzed by engineered imine reductase (RedAms) is a new and powerful tool for the synthesis of substituted chiral amines…”
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The post‐illumination pupil response of melanopsin‐expressing intrinsically photosensitive retinal ganglion cells in diabetes by Feigl, Beatrix, Zele, Andrew J., Fader, Samantha M., Howes, Annelisa N., Hughes, Catherine E., Jones, Kris A., Jones, Rawlyn

“… Purpose:  This study investigates the clinical utility of the melanopsin‐expressing intrinsically photosensitive retinal ganglion cell (ipRGC) controlled…”
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Development of a Nitrene-Type Rearrangement for the Commercial Route of the JAK1 Inhibitor Abrocitinib by Connor, Christina G, DeForest, Jacob C, Dietrich, Phil, Do, Nga M, Doyle, Kevin M, Eisenbeis, Shane, Greenberg, Elizabeth, Griffin, Sarah H, Jones, Brian P, Jones, Kris N, Karmilowicz, Michael, Kumar, Rajesh, Lewis, Chad A, McInturff, Emma L, McWilliams, J. Christopher, Mehta, Ruchi, Nguyen, Bao D, Rane, Anil M, Samas, Brian, Sitter, Barbara J, Ward, Howard W, Webster, Mark E

“…The development of a commercial route toward the JAK1 inhibitor abrocitinib is described. The application of a late-stage Lossen rearrangement provided the…”
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Streamlined Synthesis of a Bicyclic Amine Moiety Using an Enzymatic Amidation and Identification of a Novel Solid Form by Brown, Maria S, Caporello, Michaella A, Goetz, Adam E, Johnson, Amber M, Jones, Kris N, Knopf, Kevin M, Kulkarni, Samir A, Lee, Taegyo, Li, Bryan, Lu, Cuong V, Magano, Javier, Puchlopek-Dermenci, Angela L. A, Reyes, Giselle P, Ruggeri, Sally Gut, Wei, Lulin, Weisenburger, Gerald A, Wisdom, Richard A, Zhang, Mengtan

“…We describe a series of improvements to the synthesis of a 3,8-diazabicyclo[3.2.1]­octane derivative that result in a reduced step count and higher overall…”
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Large-Scale Cyclopropanation of Butyl Acrylate with Difluorocarbene and Classical Resolution of a Key Fluorinated Building Block by Goetz, Adam E, Becirovic, Husein, Blasberg, Florian, Chen, Bo, Clarke, Hugh J, Colombo, Matteo, Daddario, Pedro, Damon, David B, Depretz, Christelle, Dumond, Yves R, Grilli, Maria D, Han, Lu, Houck, Tim L, Johnson, Amber M, Jones, Kris N, Jung, Jörg, Leeman, Michel, Liu, Fangfang, Lu, Cuong V, Mangual, Emilio J, Nelson, Jade D, Puchlopek-Dermenci, Angela L. A, Ruggeri, Sally Gut, Simonds, Paul A, Sitter, Barbara, Virtue, Daniel E, Wang, Shuguang, Yu, Lixin, Yu, Tao

“…To address challenges in the preparation of a key building block containing a difluorocyclopropane moiety, we have developed a new protocol for difluorocarbene…”
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Commercial Route Research and Development for SGLT2 Inhibitor Candidate Ertugliflozin by Bowles, Paul, Brenek, Steven J, Caron, Stéphane, Do, Nga M, Drexler, Michele T, Duan, Shengquan, Dubé, Pascal, Hansen, Eric C, Jones, Brian P, Jones, Kris N, Ljubicic, Tomislav A, Makowski, Teresa W, Mustakis, Jason, Nelson, Jade D, Olivier, Mark, Peng, Zhihui, Perfect, Hahdi H, Place, David W, Ragan, John A, Salisbury, John J, Stanchina, Corey L, Vanderplas, Brian C, Webster, Mark E, Weekly, R. Matt

“…A practical synthesis of SGLT2 inhibitor candidate ertugliflozin (1) has been developed for potential commercial application. The highly telescoped process…”
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Synthesis of Filibuvir. Part III. Development of a Process for the Reductive Coupling of an Aldehyde and a β‑Keto-lactone by Ide, Nathan D, Ragan, John. A, Bellavance, Gabriel, Brenek, Steve J, Cordi, Eric M, Jensen, Grace O, Jones, Kris N, LaFrance, Danny, Leeman, Kyle R, Letendre, Leo J, Place, David, Stanchina, Corey L, Sluggett, Gregory W, Strohmeyer, Holly, Blunt, Jon, Meldrum, Kevin, Taylor, Stuart, Byrne, Ciaran, Lynch, Denis, Mullane, Sandra, O’Sullivan, Maria M, Whelan, Marcella

“…Development of a reductive coupling of a β-keto-lactone and an aldehyde is described, in which the Hantzsch ester serves as an inexpensive and convenient…”
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451: 13-Year-Old Male With Hyperglycemic Hyperosmolar Syndrome Complicated by Multiorgan System Failure by Jones, Kris, Areinamo, Igor, Thompson, Marita

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965: EVALUATION OF CLEVIDIPINE VERSUS NICARDIPINE FOR ACUTE BLOOD PRESSURE MANAGEMENT by Allen, Livia, Gunn, Jennifer, Jones, Kris, Virtue, Justin, Derenski, Karrie

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Route Optimization of the Non-covalent Modulator of Hemoglobin PF-07059013 for the Treatment of Sickle Cell Disease, Part I: From Discovery Synthesis to First Kilogram-Scale Manufacture by Baldwin, Aaron, Cabral, Shawn, Jones, Kris N., Kohrt, Jeffrey T., Limberakis, Chris, Liu, Yiyang, Magano, Javier, Monfette, Sebastien, Nematalla, Asaad, Ovaska, Sami, Piotrowski, David W., Piper, Jared L., Raggon, Jeffrey W., Thuma, Benjamin A., Wei, Liuqing

“…The scalable route to PF-07059013 (3), a non-covalent modulator of hemoglobin for the treatment of sickle cell disease, is discussed. Optimization of the…”
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Setting up a social enterprise for clinician-led lymphoedema services by Warrilow, Mary, Jones, Kris

“…The introduction of social enterprises into healthcare has brought about opportunities and challenges for providers and clinicians. Dudley Lymphoedema Service,…”
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622: EVALUATION OF PHARMACIST VS NURSE ASSESSED CONFUSION ASSESSMENT METHOD FOR THE INTENSIVE CARE UNIT by Mackley, Livia, Catlin, Jennifer, Derenski, Karrie, Seratt, Michelle, Lewis, Amy, Jones, Kris, Gunn, Jennifer

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Implementing a Multidimensional Poverty Measure Using Mixed Methods and a Participatory Framework by Mitra, Sophie, Jones, Kris, Vick, Brandon, Brown, David, McGinn, Eileen, Alexander, Mary Jane

“…Recently, there have been advances in the development of multidimensional poverty measures. Work is needed however on how to implement such measures. This…”
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Announcing the 2016-2017 Alan C. Purves Award Recipient (Volume 51) by Beck, Sarah W., Aukerman, Maren S., Boyd, Maureen, Jackson, Nicholas, Jones, Kris

“…The 2017 Alan C Purves Award Committee recognized Katherine K Frankel, of Boston University, as the recipient of this year's award for her article "The…”
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Mild and Direct Conversion of Quinoline N-Oxides to 2-Amidoquinolines with Primary Amides by Couturier, Michel, Caron, Laurence, Tumidajski, Stephanie, Jones, Kris, White, Timothy D

“…A simple, one-pot procedure is described for the direct conversion of quinoline N-oxides to α-amidoquinolines with primary amides. This methodology is…”
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Adeno-associated virus (AAV) capsid genes isolated from rat and mouse liver genomic DNA define two new AAV species distantly related to AAV-5 by Lochrie, Michael A., Tatsuno, Gwen P., Arbetman, Alejandra E., Jones, Kris, Pater, Cheryl, Smith, Peter H., McDonnell, Jennifer W., Zhou, Shang-Zhen, Kachi, Shu, Kachi, Michiko, Campochiaro, Peter A., Pierce, Glenn F., Colosi, Peter

“…Using polymerase chain reactions and genome walking strategies, adeno-associated virus (AAV)-like capsid genes were isolated from rat and mouse liver genomic…”
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The IRS and the 'Responsible Person' for Paying Employment Taxes by Whitehead, Roy, Jones, Kris

“…This article discusses the method used by the IRS to decide who is a "responsible person" when a corporation fails to remit employment taxes and what kind of…”
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Democratization and Politics in South African Townships by Cherry, Janet, Jones, Kris, Seekings, Jeremy

“…In South Africa, as in many other countries, there appears to have been a demobilization of mass urban movements following the achievement of representative…”
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The IRS and the 'responsible person' for paying employment taxes: a case study by Whitehead, Jr., Roy, Jones, Kris

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