Search Results - "Jones, Jon"

Anti-B-cell Maturation Antigen Chimeric Antigen Receptor T cell Function against Multiple Myeloma Is Enhanced in the Presence of Lenalidomide by Works, Melissa, Soni, Neha, Hauskins, Collin, Sierra, Catherine, Baturevych, Alex, Jones, Jon C, Curtis, Wendy, Carlson, Patrick, Johnstone, Timothy G, Kugler, David, Hause, Ronald J, Jiang, Yue, Wimberly, Lindsey, Clouser, Christopher R, Jessup, Heidi K, Sather, Blythe, Salmon, Ruth A, Ports, Michael O

“…Anti-B-cell maturation antigen (BCMA) chimeric antigen receptor (CAR) T cells have shown promising clinical responses in patients with relapsed/refractory…”
Get full text

Antitumor Potency of an Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy, Lisocabtagene Maraleucel in Combination With Ibrutinib or Acalabrutinib by Qin, Jim S., Johnstone, Timothy G., Baturevych, Alex, Hause, Ronald J., Ragan, Seamus P., Clouser, Christopher R., Jones, Jon C., Ponce, Rafael, Krejsa, Cecile M., Salmon, Ruth A., Ports, Michael O.

“…Chimeric antigen receptor (CAR) T-cell therapy is a promising treatment for patients with CD19+ B-cell malignancies. Combination strategies that improve CAR…”
Get full text

The α-emitter astatine-211 targeted to CD38 can eradicate multiple myeloma in a disseminated disease model by O'Steen, Shyril, Comstock, Melissa L., Orozco, Johnnie J., Hamlin, Donald K., Wilbur, D. Scott, Jones, Jon C., Kenoyer, Aimee, Nartea, Margaret E., Lin, Yukang, Miller, Brian W., Gooley, Theodore A., Tuazon, Sherilyn A., Till, Brian G., Gopal, Ajay K., Sandmaier, Brenda M., Press, Oliver W., Green, Damian J.

“…Minimal residual disease (MRD) has become an increasingly prevalent and important entity in multiple myeloma (MM). Despite deepening responses to frontline…”
Get full text

High-resolution ground-penetrating radar monitoring of soil moisture dynamics: Field results, interpretation, and comparison with unsaturated flow model by Steelman, Colby M., Endres, Anthony L., Jones, Jon P.

“…Surface ground‐penetrating radar (GPR) techniques have been used by a number of previous researchers to characterize soil moisture content in the vadose zone…”
Get full text

Understanding the water balance paradox in the Athabasca River Basin, Canada by Hwang, Hyoun‐Tae, Park, Young‐Jin, Sudicky, Edward A., Berg, Steven J., McLaughlin, Robert, Jones, Jon P.

“…This study demonstrates the importance of the including and appropriately parameterizing peatlands and forestlands for basin‐scale integrated…”
Get full text

RANK expression on breast cancer cells promotes skeletal metastasis by Blake, Michelle L., Tometsko, Mark, Miller, Robert, Jones, Jon C., Dougall, William C.

“…RANK ligand (RANKL), acting through its cognate receptor RANK, is a key factor for bone remodeling and metastasis by regulating the differentiation, survival…”
Get full text

RANKL acts directly on RANK-expressing prostate tumor cells and mediates migration and expression of tumor metastasis genes by Armstrong, Allison P., Miller, Robert E., Jones, Jon C., Zhang, Jian, Keller, Evan T., Dougall, William C.

“…BACKGROUND Metastases to bone are a frequent complication of human prostate cancer and result in the development of osteoblastic lesions that include an…”
Get full text

Astatine-211 conjugated to an anti-CD20 monoclonal antibody eradicates disseminated B-cell lymphoma in a mouse model by Green, Damian J., Shadman, Mazyar, Jones, Jon C., Frayo, Shani L., Kenoyer, Aimee L., Hylarides, Mark D., Hamlin, Donald K., Wilbur, D. Scott, Balkan, Ethan R., Lin, Yukang, Miller, Brian W., Frost, Sofia.H.L., Gopal, Ajay K., Orozco, Johnnie J., Gooley, Theodore A., Laird, Kelly L., Till, Brian G., Bäck, Tom, Sandmaier, Brenda M., Pagel, John M., Press, Oliver W.

“…α-Emitting radionuclides deposit a large amount of energy within a few cell diameters and may be particularly effective for radioimmunotherapy targeting…”
Get full text

Diagnosis and surgical management of colovesical fistulas due to sigmoid diverticulitis by Melchior, Sebastian, Cudovic, Dragan, Jones, Jon, Thomas, Christian, Gillitzer, Rolf, Thüroff, Joachim

“…Diverticular disease of the colon is the most frequent cause of colovesical fistulas. In this study we evaluated the accuracy of different diagnostic…”
Get more information

RANKL inhibition blocks osteolytic lesions and reduces skeletal tumor burden in models of non-small-cell lung cancer bone metastases by Miller, Robert E, Jones, Jon C, Tometsko, Mark, Blake, Michelle L, Dougall, William C

“…Bone metastasis is a serious complication in patients with lung cancer, occurring in up to 40% of patients. Tumor cell-mediated osteolysis occurs ultimately…”
Get more information

Incidence, clinical symptoms and management of rectourethral fistulas after radical prostatectomy by Thomas, Christian, Jones, Jon, Jäger, Wolfgang, Hampel, Christian, Thüroff, Joachim W, Gillitzer, Rolf

“…Rectourethral fistula is a rare but severe complication after radical prostatectomy and there is no standardized treatment. We retrospectively evaluated the…”
Get more information

Quantitative single‐particle digital autoradiography with α‐particle emitters for targeted radionuclide therapy using the iQID camera by Miller, Brian W., Frost, Sofia H. L., Frayo, Shani L., Kenoyer, Aimee L., Santos, Erlinda, Jones, Jon C., Green, Damian J., Hamlin, Donald K., Wilbur, D. Scott, Fisher, Darrell R., Orozco, Johnnie J., Press, Oliver W., Pagel, John M., Sandmaier, Brenda M.

“…Purpose: Alpha‐emitting radionuclides exhibit a potential advantage for cancer treatments because they release large amounts of ionizing energy over a few cell…”
Get full text

Gene Signatures of Progression and Metastasis in Renal Cell Cancer by JONES, Jon, OTU, Hasan, JONAS, Dietger, LIBERMANN, Towia A, SPENTZOS, Dimitrios, KOLIA, Shakirahmed, INAN, Mehmet, BEECKEN, Wolf D, FELLBAUM, Christian, XUESONG GU, JOSEPH, Marie, PANTUCK, Allan J

“…Purpose: To address the progression, metastasis, and clinical heterogeneity of renal cell cancer (RCC). Experimental Design: Transcriptional profiling with…”
Get full text

Assessing the impact of large-scale dewatering on fault-controlled aquifer systems: a case study in the Acque Albule basin (Tivoli, central Italy) by Brunetti, Elio, Jones, Jon P., Petitta, Marco, Rudolph, David L.

“…The development of large-scale bedrock quarry operations often requires high-volume and long-term groundwater extraction to maintain a sustainable working…”
Get full text

Decreasing susceptibility of bacteria to ampicillin/ sulbactam and third generation cephalosporins in urinary tract infections by Vallo, Stefan, Wirth, Patrick, Kukic, Adnan, Nafez, Omar, Neagoe, Ladislau, Nestler, Sebastian, Jones, Jon

“…Urinary tract infections (UTIs) are among the most common bacterial infections worldwide and have become more difficult to treat over the years. Inappropriate…”
Get full text

A simple method to assess unsaturated zone time lag in the travel time from ground surface to receptor by Sousa, Marcelo R., Jones, Jon P., Frind, Emil O., Rudolph, David L.

“…In contaminant travel from ground surface to groundwater receptors, the time taken in travelling through the unsaturated zone is known as the unsaturated zone…”
Get full text

Removal and recovery of inhibitory volatile fatty acids from mixed acid fermentations by conventional electrodialysis by Jones, Rhys Jon, Massanet-Nicolau, Jaime, Guwy, Alan, Premier, Giuliano C, Dinsdale, Richard M, Reilly, Matthew

“…Hydrogen production during dark fermentation is inhibited by the co-production of volatile fatty acids (VFAs) such as acetic and n-butyric acid. In this study,…”
Get full text

Delineating baseflow contribution areas for streams – A model and methods comparison by Chow, Reynold, Frind, Michael E., Frind, Emil O., Jones, Jon P., Sousa, Marcelo R., Rudolph, David L., Molson, John W., Nowak, Wolfgang

“…This study addresses the delineation of areas that contribute baseflow to a stream reach, also known as stream capture zones. Such areas can be delineated…”
Get full text

A Preclinical Model of CD38-Pretargeted Radioimmunotherapy for Plasma Cell Malignancies by GREEN, Damian J, ORGUN, Nural N, FRAYO, Shani L, GOPAL, Ajay K, OROZCO, Johnnie J, GOOLEY, Theodore A, WOOD, Brent L, BENSINGER, William I, PRESS, Oliver W, JONES, Jon C, HYLARIDES, Mark D, PAGEL, John M, HAMLIN, Donald K, WILBUR, D. S, YUKANG LIN, FISHER, Darrell R, KENOYER, Aimee L

“…The vast majority of patients with plasma cell neoplasms die of progressive disease despite high response rates to novel agents. Malignant plasma cells are…”
Get full text

CXCR4 Chemokine Receptor Mediates Prostate Tumor Cell Adhesion through α5 and β3 Integrins by Engl, Tobias, Relja, Boma, Marian, Dana, Blumenberg, Christa, Müller, Iris, Beecken, Wolf-Dietrich, Jones, Jon, Ringel, Eva M., Bereiter-Hahn, Jürgen, Jonas, Dietger, Blaheta, Roman A.

“…The mechanisms leading to prostate cancer metastasis are not understood completely. Although there is evidence that the CXC chemokine receptor (CXCR) 4 and its…”
Get full text