Search Results - "Jones, Jace"

Utilization of LC-MS/MS and Drift Tube Ion Mobility for Characterizing Intact Oxidized Arachidonate-Containing Glycerophosphatidylethanolamine by Morel, Yulemni, Jones, Jace W

“…Lipid peroxidation is a key component in the pathogenesis of numerous disease states, where the oxidative damage of lipids frequently leads to membrane…”
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Sphingolipid metabolism as a marker of hepatotoxicity in drug-induced liver injury by Li, Linhao, Wang, Hongbing, Jones, Jace W.

“…[Display omitted] •Multidimensional mass spectrometry datasets for sphingolipid structure analysis.•Characterization of sphingolipid structure from human…”
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PLA2G4A/cPLA2-mediated lysosomal membrane damage leads to inhibition of autophagy and neurodegeneration after brain trauma by Sarkar, Chinmoy, Jones, Jace W., Hegdekar, Nivedita, Thayer, Julia A., Kumar, Alok, Faden, Alan I., Kane, Maureen A., Lipinski, Marta M.

“…Lysosomal membrane permeabilization (LMP) is observed under many pathological conditions, leading to cellular dysfunction and death. However, the mechanisms by…”
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Review of the 2023 Fall Workshop on LipidomicsThe Essentials to the Cutting Edge by Garrett, Timothy J, Jones, Jace W

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Differential utilization of vitamin B12-dependent and independent pathways for propionate metabolism across human cells by Gouda, Harsha, Ji, Yuanyuan, Rath, Sneha, Watkins, David, Rosenblatt, David, Mootha, Vamsi, Jones, Jace W., Banerjee, Ruma

“…Propionic acid links the oxidation of branched-chain amino acids and odd-chain fatty acids to the TCA cycle. Gut microbes ferment complex fiber remnants,…”
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Use of Fast HPLC Multiple Reaction Monitoring Cubed for Endogenous Retinoic Acid Quantification in Complex Matrices by Jones, Jace W, Pierzchalski, Keely, Yu, Jianshi, Kane, Maureen A

“…Retinoic acid (RA), an essential active metabolite of vitamin A, controls numerous physiological processes. In addition to the analytical challenges owing to…”
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All-Trans Retinoic Acid Activity in Acute Myeloid Leukemia: Role of Cytochrome P450 Enzyme Expression by the Microenvironment by Su, Meng, Alonso, Salvador, Jones, Jace W, Yu, Jianshi, Kane, Maureen A, Jones, Richard J, Ghiaur, Gabriel

“…Differentiation therapy with all-trans retinoic acid (atRA) has markedly improved outcome in acute promyelocytic leukemia (APL) but has had little clinical…”
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Atp7b-dependent choroid plexus dysfunction causes transient copper deficit and metabolic changes in the developing mouse brain by Washington-Hughes, Clorissa L, Roy, Shubhrajit, Seneviratne, Herana Kamal, Karuppagounder, Senthilkumar S, Morel, Yulemni, Jones, Jace W, Zak, Alex, Xiao, Tong, Boronina, Tatiana N, Cole, Robert N, Bumpus, Namandjé N, Chang, Christopher J, Dawson, Ted M, Lutsenko, Svetlana

“…Copper (Cu) has a multifaceted role in brain development, function, and metabolism. Two homologous Cu transporters, Atp7a (Menkes disease protein) and Atp7b…”
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Structure-specific, accurate quantitation of plasmalogen glycerophosphoethanolamine by Morel, Yulemni, Hegdekar, Nivedita, Sarkar, Chinmoy, Lipinski, Marta M., Kane, Maureen A., Jones, Jace W.

“…Changes in plasmalogen glycerophosphoethanolamine (PE-P) composition (structure and abundance) are a key indicator of altered lipid metabolism. Differential…”
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Hydrogen sulfide stimulates lipid biogenesis from glutamine that is dependent on the mitochondrial NAD(P)H pool by Carballal, Sebastian, Vitvitsky, Victor, Kumar, Roshan, Hanna, David A., Libiad, Marouane, Gupta, Aditi, Jones, Jace W., Banerjee, Ruma

“…Mammalian cells synthesize H2S from sulfur-containing amino acids and are also exposed to exogenous sources of this signaling molecule, notably from gut…”
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Unique Structural Modifications Are Present in the Lipopolysaccharide from Colistin-Resistant Strains of Acinetobacter baumannii by PELLETIER, Mark R, CASELLA, Leila G, JONES, Jace W, ADAMS, Mark D, ZURAWSKI, Daniel V, HAZLETT, Karsten R. O, DOI, Yohei, ERNST, Robert K

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Development and evaluation of a liquid chromatography-tandem mass spectrometry method for simultaneous measurement of toxic aldehydes from brain tissue by Ji, Yuanyuan, Morel, Yulemni, Tran, Anh Q., Lipinski, Marta M., Sarkar, Chinmoy, Jones, Jace W.

“…•Accurate quantitation of reactive aldehydes in brain.•3-NPH improve sensitivity for detecting aldehydes.•Sample pretreatment and derivatization were optimized…”
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Lithium Hydroxide Hydrolysis Combined with MALDI TOF Mass Spectrometry for Rapid Sphingolipid Detection by Tran, Anh, Wan, Liting, Xu, Zhenbo, Haro, Janette M, Li, Bing, Jones, Jace W

“…Sphingolipids have diverse structural and bioactive functions that play important roles in many key biological processes. Factors such as low relative…”
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Characterization of the cellular lipid composition during SARS-CoV-2 infection by Abdel-Megied, Ahmed M., Monreal, Isaac A., Zhao, Limian, Apffel, Alex, Aguilar, Hector C., Jones, Jace W.

“…Emerging and re-emerging zoonotic viral diseases continue to significantly impact public health. Of particular interest are enveloped viruses (e.g.,…”
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Two functionally redundant sources of retinoic acid secure spermatogonia differentiation in the seminiferous epithelium by Teletin, Marius, Vernet, Nadège, Yu, Jianshi, Klopfenstein, Muriel, Jones, Jace W, Féret, Betty, Kane, Maureen A, Ghyselinck, Norbert B, Mark, Manuel

“…In mammals, all- retinoic acid (ATRA) is instrumental to spermatogenesis. It is synthesized by two retinaldehyde dehydrogenases (RALDH) present in both Sertoli…”
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Sustained virologic control in SIV⁺ macaques after antiretroviral and α₄β₇ antibody therapy by Byrareddy, Siddappa N., Arthos, James, Cicala, Claudia, Villinger, Francois, Ortiz, Kristina T., Little, Dawn, Sidell, Neil, Kane, Maureen A., Yu, Jianshi, Jones, Jace W., Santangelo, Philip J., Zurla, Chiara, McKinnon, Lyle R., Arnold, Kelly B., Woody, Caroline E., Walter, Lutz, Roos, Christian, Noll, Angela, Van Ryk, Donald, Jelicic, Katija, Cimbro, Raffaello, Gumber, Sanjeev, Reid, Michelle D., Adsay, Volkan, Amancha, Praveen K., Mayne, Ann E., Parslow, Tristram G., Fauci, Anthony S., Ansari, Aftab A.

“…Antiretroviral drug therapy (ART) effectively suppresses replication of both the immunodeficiency viruses, human (HIV) and simian (SIV); however, virus…”
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Hepatic CYP2B10 is highly induced by binge ethanol and contributes to acute‐on‐chronic alcohol‐induced liver injury by Mackowiak, Bryan, Xu, Mingjiang, Lin, Yuhong, Guan, Yukun, Seo, Wonhyo, Ren, Ruixue, Feng, Dechun, Jones, Jace W., Wang, Hongbing, Gao, Bin

“…Background The chronic‐plus‐binge model of ethanol consumption, where chronically (8‐week) ethanol‐fed mice are gavaged a single dose of ethanol (E8G1), is…”
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Electron-induced dissociation (EID) for structure characterization of glycerophosphatidylcholine: determination of double-bond positions and localization of acyl chains by Jones, Jace W., Thompson, Christopher J., Carter, Claire L., Kane, Maureen A.

“…Glycerophospholipids are a highly abundant and diverse collection of biologically relevant lipids, and distinction between isomeric and isobaric species is a…”
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Tom20 gates PINK1 activity and mediates its tethering of the TOM and TIM23 translocases upon mitochondrial stress by Eldeeb, Mohamed A, Bayne, Andrew N, Fallahi, Armaan, Goiran, Thomas, MacDougall, Emma J, Soumbasis, Andrea, Zorca, Cornelia E, Tabah, Jace-Jones, Thomas, Rhalena A, Karpilovsky, Nathan, Mathur, Meghna, Durcan, Thomas M, Trempe, Jean-François, Fon, Edward A

“…Mutations in PTEN-induced putative kinase 1 (PINK1) cause autosomal recessive early-onset Parkinson's disease (PD). PINK1 is a Ser/Thr kinase that regulates…”
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Noncoding dsRNA induces retinoic acid synthesis to stimulate hair follicle regeneration via TLR3 by Kim, Dongwon, Chen, Ruosi, Sheu, Mary, Kim, Noori, Kim, Sooah, Islam, Nasif, Wier, Eric M., Wang, Gaofeng, Li, Ang, Park, Angela, Son, Wooyang, Evans, Benjamin, Yu, Victoria, Prizmic, Vicky P., Oh, Eugene, Wang, Zixiao, Yu, Jianshi, Huang, Weiliang, Archer, Nathan K., Hu, Zhiqi, Clemetson, Nashay, Nelson, Amanda M., Chien, Anna, Okoye, Ginette A., Miller, Lloyd S., Ghiaur, Gabriel, Kang, Sewon, Jones, Jace W., Kane, Maureen A., Garza, Luis A.

“…How developmental programs reactivate in regeneration is a fundamental question in biology. We addressed this question through the study of Wound Induced Hair…”
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