Search Results - "Jones, J. Howard"
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Social hierarchy and enrolment in government and private schools in rural India: longitudinal evidence from a Rajasthan village
Published in Oxford review of education (01-06-2018)“…With reference to a village in a predominantly tribal part of Rajasthan, this paper illustrates the increasing heterogeneity of the rural educational landscape…”
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Discovery of 3-[(4,5,7-Trifluorobenzothiazol-2-yl)methyl]indole-N-acetic Acid (Lidorestat) and Congeners as Highly Potent and Selective Inhibitors of Aldose Reductase for Treatment of Chronic Diabetic Complications
Published in Journal of medicinal chemistry (05-05-2005)“…Recent efforts to identify treatments for chronic diabetic complications have resulted in the discovery of a novel series of highly potent and selective…”
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Rational Design and Optimization of a Novel Class of Macrocyclic Apoptosis Signal-Regulating Kinase 1 Inhibitors
Published in Journal of medicinal chemistry (12-12-2019)“…Structural analysis of a known apoptosis signal-regulating kinase 1 (ASK1) inhibitor bound to its kinase domain led to the design and synthesis of the novel…”
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Discovery of Potent, Selective, and Brain-Penetrant Apoptosis Signal-Regulating Kinase 1 (ASK1) Inhibitors that Modulate Brain Inflammation In Vivo
Published in Journal of medicinal chemistry (28-10-2021)“…Apoptosis signal-regulating kinase 1 (ASK1) is one of the key mediators of the cellular stress response that regulates inflammation and apoptosis. To probe the…”
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Discovery of Potent and Brain-Penetrant Tau Tubulin Kinase 1 (TTBK1) Inhibitors that Lower Tau Phosphorylation In Vivo
Published in Journal of medicinal chemistry (13-05-2021)“…Structural analysis of the known NIK inhibitor 3 bound to the kinase domain of TTBK1 led to the design and synthesis of a novel class of azaindazole TTBK1…”
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Discovery and Preclinical Characterization of BIIB129, a Covalent, Selective, and Brain-Penetrant BTK Inhibitor for the Treatment of Multiple Sclerosis
Published in Journal of medicinal chemistry (23-05-2024)“…Multiple sclerosis (MS) is a chronic disease with an underlying pathology characterized by inflammation-driven neuronal loss, axonal injury, and demyelination…”
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Informal finance and rural finance policy in India: historical and contemporary perspectives
Published in Contemporary South Asia (01-09-2008)“…From the 1950s up to the early 1990s the All-India data show an ever-declining share of informal credit in the total outstanding debt of rural households…”
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Training to address attitudes and behaviour of rural bank managers in Madhya Pradesh, India: A programme to facilitate financial inclusion
Published in Journal of international development (01-08-2007)“…Given their physical presence in India, banks are arguably well‐placed to improve financial inclusion in rural areas. However, uncertain repayment capacities…”
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Discovery of CNS-Penetrant Apoptosis Signal-Regulating Kinase 1 (ASK1) Inhibitors
Published in ACS medicinal chemistry letters (09-04-2020)“…Apoptosis signal-regulating kinase 1 (ASK1) is a key mediator in the apoptotic and inflammatory cellular stress response. To investigate the therapeutic value…”
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Integration of optimized substituent patterns to produce highly potent 4-aryl-pyridine glucagon receptor antagonists
Published in Bioorganic & medicinal chemistry letters (02-12-2002)“…Optimized substituent patterns in 4-aryl-pyridine glucagon receptor antagonists were merged to produce highly potent derivatives containing both a 3-[(1…”
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Optimization of the 4-aryl group of 4-aryl-pyridine glucagon antagonists: development of an efficient, alternative synthesis
Published in Bioorganic & medicinal chemistry letters (06-05-2002)“…A narrow structure–activity relationship was established for the 4-aryl group in 4-aryl-pyridine glucagon antagonists, with only small substituents being…”
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Biographical Sketches of Members of the 1868 Louisiana State Senate
Published in Louisiana history (01-01-1978)Get full text
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Optimizing use of assisted reproduction
Published in American journal of obstetrics and gynecology (01-08-2003)“…Infertile couples who have failed to achieve pregnancy now have new options that have become available in the last two decades. The costs are generally large…”
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Surface Morphology of the Human Endometrium: Basic and Clinical Aspects
Published in Annals of the New York Academy of Sciences (01-01-2000)“…: The human endometrium is an extremely sensitive target for steroid hormones. During the menstrual cycle, this tissue undergoes dynamic changes that are…”
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Letters in Protest of Race Prejudice in the Army during the American Civil War
Published in The Journal of Negro history (01-01-1976)Get full text
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Two Letters in Protest of Race Prejudice in the Army During the American Civil War
Published in The Journal of Negro history (01-01-1976)Get full text
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Lansing Community College Reading Study
Published 10-04-1979“…The Reading Progress Scale (RPS) was administered to 4,714 students from 46 courses ranging from accounting to welding at Lansing Community College in two…”
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