Search Results - "Jones, George"

Joint Vestibular Schwannoma Enlargement Prediction and Segmentation Using a Deep Multi-task Model by Wang, Kai, George-Jones, Nicholas A, Chen, Liyuan, Hunter, Jacob B, Wang, Jing

“…To develop a deep-learning-based multi-task (DMT) model for joint tumor enlargement prediction (TEP) and automatic tumor segmentation (TS) for vestibular…”
Get full text

Automated Detection of Vestibular Schwannoma Growth Using a Two‐Dimensional U‐Net Convolutional Neural Network by George‐Jones, Nicholas A., Wang, Kai, Wang, Jing, Hunter, Jacob B.

“…Objectives/Hypothesis To determine if an automated vestibular schwannoma (VS) segmentation model has comparable performance to using the greatest linear…”
Get full text

Streptomyces RNases - Function and impact on antibiotic synthesis by Jones, George H

“…are soil dwelling bacteria that are notable for their ability to sporulate and to produce antibiotics and other secondary metabolites. Antibiotic biosynthesis…”
Get full text

MRI Texture Features are Associated with Vestibular Schwannoma Histology by George‐Jones, Nicholas A., Chkheidze, Rati, Moore, Samantha, Wang, Jing, Hunter, Jacob B.

“…Objectives/Hypothesis To determine if commonly used radiomics features have an association with histological findings in vestibular schwannomas (VS). Study…”
Get full text

Phylogeny and Evolution of RNA 3′-Nucleotidyltransferases in Bacteria by Jones, George H.

“…The tRNA nucleotidyltransferases and poly(A) polymerases belong to a superfamily of nucleotidyltransferases. The amino acid sequences of a number of bacterial…”
Get full text

Comet Assay Profiling of FLASH-Induced Damage: Mechanistic Insights into the Effects of FLASH Irradiation by Cooper, Christian R, Jones, Donald J L, Jones, George D D, Petersson, Kristoffer

“…Numerous studies have demonstrated the normal tissue-sparing effects of ultra-high dose rate 'FLASH' irradiation in vivo, with an associated reduction in…”
Get full text

SIP1 protein protects cells from DNA damage-induced apoptosis and has independent prognostic value in bladder cancer by Sayan, A. Emre, Griffiths, Thomas R, Pal, Raj, Browne, Gareth J, Ruddick, Andrew, Yagci, Tamer, Edwards, Richard, Mayer, Nick J, Qazi, Hasan, Goyal, Sandeep, Fernandez, Serena, Straatman, Kees, Jones, George D.D, Bowman, Karen J, Colquhoun, Alexandra, Mellon, J. Kilian, Kriajevska, Marina, Tulchinsky, Eugene

“…The epithelial-mesenchymal transition (EMT) contributes to cancer metastasis. Two ZEB family members, ZEB1 and ZEB2(SIP1), inhibit transcription of the…”
Get full text

FLASH irradiation induces lower levels of DNA damage ex vivo, an effect modulated by oxygen tension, dose, and dose rate by Cooper, Christian R, Jones, Donald, Jones, George Dd, Petersson, Kristoffer

“…FLASH irradiation reportedly produces less normal tissue toxicity, while maintaining tumour response. To investigate oxygen's role in the 'FLASH effect', we…”
Get full text

Lateral variability in clinoform trajectory, process regime, and sediment dispersal patterns beyond the shelf-edge rollover in exhumed basin margin-scale clinothems by Jones, George E. D., Hodgson, David M., Flint, Stephen S.

“…Sediment supply rate and accommodation regime represent primary controls on the depositional architecture of basin margin successions, but their interaction is…”
Get full text

Loss of Nek11 Prevents G2/M Arrest and Promotes Cell Death in HCT116 Colorectal Cancer Cells Exposed to Therapeutic DNA Damaging Agents by Sabir, Sarah R, Sahota, Navdeep K, Jones, George D D, Fry, Andrew M

“…The Nek11 kinase is a potential mediator of the DNA damage response whose expression is upregulated in early stage colorectal cancers (CRCs). Here, using…”
Get full text

Clovis and Western Stemmed: Population Migration and the Meeting of Two Technologies in the Intermountain West by Beck, Charlotte, Jones, George T.

“…The Intermountain West is rarely included in discussions of the North American Paleoindian record, largely because there is so little evidence for Clovis in…”
Get full text

Calibration of the comet assay using ionising radiation by Brunborg, Gunnar, Eide, Dag M., Graupner, Anne, Gutzkow, Kristine, Shaposhnikov, Sergey, Kruszewski, Marcin, Sirota, Nikolai, Jones, George D.D., Koppen, Gudrun, Vanhavere, Filip, Møller, Peter, Stetina, Rudolf, Dahl, Hildegunn, Collins, Andrew

“…Several trials have attempted to identify sources of inter-laboratory variability in comet assay results, aiming at achieving more equal responses. Ionising…”
Get full text

ATM Regulates Differentiation of Myofibroblastic Cancer-Associated Fibroblasts and Can Be Targeted to Overcome Immunotherapy Resistance by Mellone, Massimiliano, Piotrowska, Klaudia, Venturi, Giulia, James, Lija, Bzura, Aleksandra, Lopez, Maria A, James, Sonya, Wang, Chuan, Ellis, Matthew J, Hanley, Christopher J, Buckingham, Josephine F, Cox, Kerry L, Hughes, Gareth, Valge-Archer, Viia, King, Emma V, Beers, Stephen A, Jaquet, Vincent, Jones, George D D, Savelyeva, Natalia, Sayan, Emre, Parsons, Jason L, Durant, Stephen, Thomas, Gareth J

“…Myofibroblastic cancer-associated fibroblast (myoCAF)-rich tumors generally contain few T cells and respond poorly to immune-checkpoint blockade. Although…”
Get full text

MTH1 deficiency selectively increases non-cytotoxic oxidative DNA damage in lung cancer cells: more bad news than good? by Abbas, Hussein H K, Alhamoudi, Kheloud M H, Evans, Mark D, Jones, George D D, Foster, Steven S

“…Targeted therapies are based on exploiting cancer-cell-specific genetic features or phenotypic traits to selectively kill cancer cells while leaving normal…”
Get full text

Influence of skin melanisation and ultraviolet radiation on biomarkers of systemic oxidative stress by Shih, Barbara B., Farrar, Mark D., Vail, Andy, Allan, Donald, Chao, Mu-Rong, Hu, Chiung-Wen, Jones, George D.D., Cooke, Marcus S., Rhodes, Lesley E.

“…Skin melanisation ranges widely across human populations. Melanin has antioxidant properties and also acts as a filter to solar ultraviolet radiation (UVR)…”
Get full text

BTK Modulates p53 Activity to Enhance Apoptotic and Senescent Responses by Althubiti, Mohammad, Rada, Miran, Samuel, Jesvin, Escorsa, Josep M, Najeeb, Hishyar, Lee, Koon-Guan, Lam, Kong-Peng, Jones, George D D, Barlev, Nickolai A, Macip, Salvador

“…p53 is a tumor suppressor that prevents the emergence of transformed cells by inducing apoptosis or senescence, among other responses. Its functions are…”
Get full text

Epitaxial graphene homogeneity and quantum Hall effect in millimeter-scale devices by Yang, Yanfei, Cheng, Guangjun, Mende, Patrick, Calizo, Irene G., Feenstra, Randall M., Chuang, Chiashain, Liu, Chieh-Wen, Liu, Chieh-I., Jones, George R., Hight Walker, Angela R., Elmquist, Randolph E.

“…Quantized magnetotransport is observed in 5.6 × 5.6 mm2 epitaxial graphene devices, grown using highly constrained sublimation on the Si-face of SiC(0001) at…”
Get full text

Acquisition of pcnB [poly(A) polymerase I] genes via horizontal transfer from the β, γ- Proteobacteria by Jones, George H

“…Poly(A) polymerases (PAPs) and tRNA nucleotidyltransferases belong to a superfamily of nucleotidyltransferases and modify RNA 3'-ends. The product of the gene,…”
Get full text

Gene expression profiling reveals new protective roles for vitamin C in human skin cells by Duarte, Tiago L., Cooke, Marcus S., Jones, George D.D.

“…The skin is a protective barrier against external insults and any lesion must be rapidly and efficiently repaired. Dermal fibroblasts are the major source of…”
Get full text

Prediction of Vestibular Schwannoma Enlargement After Radiosurgery Using Tumor Shape and MRI Texture Features by George-Jones, Nicholas A., Wang, Kai, Wang, Jing, Hunter, Jacob B.

“…OBJECTIVE:Determine if vestibular schwannoma (VS) shape and MRI texture features predict significant enlargement after stereotactic radiosurgery (SRS). STUDY…”
Get full text