Search Results - "Jones, Gavin C."
-
1
Whole-Body Vibration Prevents Neuronal, Neurochemical, and Behavioral Effects of Morphine Withdrawal in a Rat Model
Published in International journal of molecular sciences (15-09-2023)“…Peripheral mechanoreceptor-based treatments such as acupuncture and chiropractic manipulation have shown success in modulating the mesolimbic dopamine (DA)…”
Get full text
Journal Article -
2
Mechanical Stimulation Alters Chronic Ethanol-Induced Changes to VTA GABA Neurons, NAc DA Release and Measures of Withdrawal
Published in International journal of molecular sciences (20-10-2022)“…Therapeutic activation of mechanoreceptors (MStim) in osteopathy, chiropractic and acupuncture has been in use for hundreds of years with a myriad of positive…”
Get full text
Journal Article -
3
The regulation of aggrecanase ADAMTS-4 expression in human Achilles tendon and tendon-derived cells
Published in Matrix biology (01-06-2008)“…Several members of the ADAMTS (A Disintegrin And Metalloproteinase with ThromboSpondin motifs) family have been identified as aggrecanases, whose substrates…”
Get full text
Journal Article -
4
Cyclical strain modulates metalloprotease and matrix gene expression in human tenocytes via activation of TGFβ
Published in Biochimica et biophysica acta (01-12-2013)“…Tendinopathies are a range of diseases characterised by degeneration and chronic tendon pain and represent a significant cause of morbidity. Relatively little…”
Get full text
Journal Article -
5
Catharanthine Modulates Mesolimbic Dopamine Transmission and Nicotine Psychomotor Effects via Inhibition of α6-Nicotinic Receptors and Dopamine Transporters
Published in ACS chemical neuroscience (01-05-2024)“…Iboga alkaloids, also known as coronaridine congeners, have shown promise in the treatment of alcohol and opioid use disorders. The objective of this study was…”
Get full text
Journal Article -
6
ADAMTS proteinases: a multi-domain, multi-functional family with roles in extracellular matrix turnover and arthritis
Published in Arthritis research & therapy (01-01-2005)“…Members of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family are known to influence development, angiogenesis, coagulation and…”
Get full text
Journal Article -
7
-
8
Selective inhibition of ADAMTS‐1, ‐4 and ‐5 by catechin gallate esters
Published in European journal of biochemistry (01-06-2003)“…Three mammalian ADAMTS enzymes, ADAMTS‐1, ‐4 and ‐5, are known to cleave aggrecan at certain glutamyl bonds and are considered to be largely responsible for…”
Get full text
Journal Article -
9
The effect of sulfide concentrate mineralogy and texture on Reactive Oxygen Species (ROS) generation
Published in Applied geochemistry (01-02-2013)“…► Metal-containing sulfide mineral concentrates generate ROS (H2O2+OH). ► ROS generation linked to decreased thermophilic bioleaching performance. ► ROS…”
Get full text
Journal Article -
10
A novel microwell-based analytical technique for studying ferrous iron biooxidation activity
Published in Minerals engineering (01-06-2014)“…•Fe oxidation activity of a mixed bioleaching culture was monitored in a microwell plate apparatus.•Comparable growth and iron oxidation trends to shake flasks…”
Get full text
Journal Article -
11
Expression profiling of metalloproteinases and tissue inhibitors of metalloproteinases in normal and degenerate human achilles tendon
Published in Arthritis and rheumatism (01-03-2006)“…Objective To profile the messenger RNA (mRNA) expression for the 23 known genes of matrix metalloproteinases (MMPs), 19 genes of ADAMTS, 4 genes of tissue…”
Get full text
Journal Article -
12
The role of proteases in pathologies of the synovial joint
Published in The international journal of biochemistry & cell biology (01-01-2008)“…Synovial (diarthrodial) joints are employed within the body to provide skeletal mobility and have a characteristic structure adapted to provide a smooth almost…”
Get full text
Journal Article -
13
Expression of recombinant ADAMTS in insect cells
Published in Methods in molecular biology (Clifton, N.J.) (2010)“…The "a disintegrin and metalloproteinase with thrombospondin motifs" (ADAMTS) enzymes are secreted proteinases involved in development, blood clotting and the…”
Get more information
Journal Article -
14
A method for the non-covalent immobilization of heparin to surfaces
Published in Analytical biochemistry (01-07-2004)“…The interaction of heparan sulfate (HS) with specific proteins facilitates a wide range of fundamental biological processes including cellular proliferation…”
Get full text
Journal Article -
15
ADAMTS proteinases: potential therapeutic targets?
Published in Current pharmaceutical biotechnology (01-02-2006)“…ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) proteinases have been implicated in a number of connective tissue pathologies including…”
Get more information
Journal Article -
16
ADAMTS-4 activity on a proteoglycan vs. a polypeptide is controlled by the ancillary domains
Published in International journal of experimental pathology (01-08-2004)“…Introduction In combination with the catalytic domain, the ancillary domains of the ADAMTS' are proposed to regulate activity via interactions with sulfated…”
Get full text
Journal Article -
17
Grappling with the glycome
Published in International journal of experimental pathology (01-08-2004)Get full text
Journal Article -
18
The generation of toxic reactive oxygen species (ROS) from mechanically activated sulphide concentrates and its effect on thermophilic bioleaching
Published in Minerals engineering (01-09-2011)“…► A planetary and vibratory mill was used to mechanically activate pyrite and chalcopyrite. ► XRD line profile analysis showed that planetary milled samples…”
Get full text
Journal Article