Search Results - "Jones, E. Ellen"

MALDI imaging mass spectrometry: an emerging tool in neurology by Schnackenberg, Laura K., Thorn, David A., Barnette, Dustyn, Jones, E. Ellen

“…Neurological disease and disorders remain a large public health threat. Thus, research to improve early detection and/or develop more effective treatment…”
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Matrix Assisted Laser Desorption Ionization Imaging Mass Spectrometry Workflow for Spatial Profiling Analysis of N‑Linked Glycan Expression in Tissues by Powers, Thomas W., Jones, E. Ellen, Betesh, Lucy R., Romano, Patrick R., Gao, Peng, Copland, John A., Mehta, Anand S., Drake, Richard R.

“…A new matrix assisted laser desorption ionization imaging mass spectrometry (MALDI-IMS) method to spatially profile the location and distribution of multiple…”
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Radiation-induced acid ceramidase confers prostate cancer resistance and tumor relapse by Cheng, Joseph C, Bai, Aiping, Beckham, Thomas H, Marrison, S Tucker, Yount, Caroline L, Young, Katherine, Lu, Ping, Bartlett, Anne M, Wu, Bill X, Keane, Barry J, Armeson, Kent E, Marshall, David T, Keane, Thomas E, Smith, Michael T, Jones, E Ellen, Drake, Jr, Richard R, Bielawska, Alicja, Norris, James S, Liu, Xiang

“…Escape of prostate cancer (PCa) cells from ionizing radiation-induced (IR-induced) killing leads to disease progression and cancer relapse. The influence of…”
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The Sphingosine Kinase 2 Inhibitor ABC294640 Reduces the Growth of Prostate Cancer Cells and Results in Accumulation of Dihydroceramides In Vitro and In Vivo by Venant, Heather, Rahmaniyan, Mehrdad, Jones, E Ellen, Lu, Ping, Lilly, Michael B, Garrett-Mayer, Elizabeth, Drake, Richard R, Kraveka, Jacqueline M, Smith, Charles D, Voelkel-Johnson, Christina

“…Despite recent advances in the development of novel therapies against castration-resistant prostate cancer, the advanced form of the disease remains a major…”
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On-Tissue Localization of Ceramides and Other Sphingolipids by MALDI Mass Spectrometry Imaging by Jones, E. Ellen, Dworski, Shaalee, Canals, Daniel, Casas, Josefina, Fabrias, Gemma, Schoenling, Drew, Levade, Thierry, Denlinger, Chadrick, Hannun, Yusuf A, Medin, Jeffrey A, Drake, Richard R

“…A novel MALDI-FTICR imaging mass spectrometry (MALDI-IMS) workflow is described for on-tissue detection, spatial localization, and structural confirmation of…”
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A2E and lipofuscin distributions in macaque retinal pigment epithelium are similar to human by Pallitto, Patrick, Ablonczy, Zsolt, Jones, E Ellen, Drake, Richard R, Koutalos, Yiannis, Crouch, Rosalie K, Donello, John, Herrmann, Julia

“…The accumulation of lipofuscin, an autofluorescent aging marker, in the retinal pigment epithelium (RPE) has been implicated in the development of age-related…”
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Altered Glycosylation in Prostate Cancer by Drake, Richard R, Jones, E Ellen, Powers, Thomas W, Nyalwidhe, Julius O

“…Prostate cancer is annually the most common newly diagnosed cancer in men. The prostate functions as a major secretory gland for the production of…”
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In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine by Principe, Simona, Jones, E. Ellen, Kim, Yunee, Sinha, Ankit, Nyalwidhe, Julius O., Brooks, Jasmin, Semmes, O. John, Troyer, Dean A., Lance, Raymond S., Kislinger, Thomas, Drake, Richard R.

“…Expressed prostatic secretions (EPS) are proximal fluids of the prostate that are increasingly being utilized as a clinical source for diagnostic and…”
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Utility of Deep inspiration breath-hold for left sided breast radiation therapy in preventing early cardiac perfusion defects - A Prospective Study by Zagar, Timothy, MD, Kaidar - Person, Orit, Tang, Xiaoli, Jones, Ellen, Matney, Jason, Das, Shiva, Green, Rebecca L, Sheikh, Arif, Khandani, Amir H, McCartney, William H, Oldan, Jorge Daniel, Wong, Terence Z, Marks, Lawrence Bruce

“…Abstract Purpose To evaluate early cardiac single photon computed tomography (SPECT) findings after left breast/chest wall postoperative radiation therapy (RT)…”
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Feasibility Assessment of a MALDI FTICR Imaging Approach for the 3D Reconstruction of a Mouse Lung by Jones, E. Ellen, Quiason, Cristine, Dale, Stephanie, Shahidi-Latham, Sheerin K.

“…Matrix assisted laser desorption ionization imaging mass spectrometry (MALDI IMS) has proven to be a quick, robust, and label-free tool to produce…”
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Renal glycosphingolipid metabolism is dysfunctional in lupus nephritis by Nowling, Tamara K, Mather, Andrew R, Thiyagarajan, Thirumagal, Hernández-Corbacho, María José, Powers, Thomas W, Jones, E Ellen, Snider, Ashley J, Oates, Jim C, Drake, Richard R, Siskind, Leah J

“…Nearly one half of patients with lupus develop glomerulonephritis (GN), which often leads to renal failure. Although nephritis is diagnosed by the presence of…”
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Acid Ceramidase Deficiency in Mice Results in a Broad Range of Central Nervous System Abnormalities by Sikora, Jakub, Dworski, Shaalee, Jones, E. Ellen, Kamani, Mustafa A, Micsenyi, Matthew C, Sawada, Tomo, Le Faouder, Pauline, Bertrand-Michel, Justine, Dupuy, Aude, Dunn, Christopher K, Xuan, Ingrid Cong Yang, Casas, Josefina, Fabrias, Gemma, Hampson, David R, Levade, Thierry, Drake, Richard R, Medin, Jeffrey A, Walkley, Steven U

“…Farber disease is a rare autosomal recessive disorder caused by acid ceramidase deficiency that usually presents as early-onset progressive visceral and…”
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Providing Nicotine Replacement Therapy in Focus Groups by Jones, Ellen E., Jarman, Kristen L., Goldstein, Adam O.

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Increased bisecting N-acetylglucosamine and decreased branched chain glycans of N-linked glycoproteins in expressed prostatic secretions associated with prostate cancer progression by Nyalwidhe, Julius O., Betesh, Lucy R., Powers, Thomas W., Jones, E. Ellen, White, Krista Y., Burch, Tanya C., Brooks, Jasmin, Watson, Megan T., Lance, Raymond S., Troyer, Dean A., Semmes, O. John, Mehta, Anand, Drake, Richard R.

“…Purpose Using prostatic fluids rich in glycoproteins like prostate‐specific antigen and prostatic acid phosphatase (PAP), the goal of this study was to…”
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Cryopreservation of viable human lung tissue for versatile post-thaw analyses and culture by Baatz, John E, Newton, Danforth A, Riemer, Ellen C, Denlinger, Chadrick E, Jones, E Ellen, Drake, Richard R, Spyropoulos, Demetri D

“…Clinical trials are currently used to test therapeutic efficacies for lung cancer, infections and diseases. Animal models are also used as surrogates for human…”
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Targeted glycoprotein enrichment and identification in stromal cell secretomes using azido sugar metabolic labeling by Roper, Stephen M., Zemskova, Marina, Neely, Benjamin A., Martin, Arch, Gao, Peng, Jones, E. Ellen, Kraft, Andrew S., Drake, Richard R.

“…Purpose Effectively identifying the proteins present in the cellular secretome is complicated due to the presence of cellular protein leakage and serum protein…”
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Challenges to developing proteomic-based breast cancer diagnostics by Drake, Richard R, Cazares, Lisa H, Jones, E Ellen, Fuller, Thomas W, Semmes, O John, Laronga, Christine

“…Over the past decade, multiple genetic and histological approaches have accelerated development of new breast cancer diagnostics and treatment paradigms…”
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MALDI Mass Spectrometry Imaging of N-Linked Glycans in Cancer Tissues by Drake, R R, Powers, T W, Jones, E E, Bruner, E, Mehta, A S, Angel, P M

“…Glycosylated proteins account for a majority of the posttranslation modifications of cell surface, secreted, and circulating proteins. Within the tumor…”
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Oral health and overall health. The mouth can tell the tale by Jones, Ellen E

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MALDI imaging mass spectrometry profiling of proteins and lipids in clear cell renal cell carcinoma by Jones, Elizabeth Ellen, Powers, Thomas W., Neely, Benjamin A., Cazares, Lisa H., Troyer, Dean A., Parker, Alexander S., Drake, Richard R.

“…Reducing the incidence and mortality rates for clear cell renal cell carcinoma (ccRCC) remains a significant clinical challenge with poor 5‐year survival…”
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