Search Results - "Jones, Daniel T.D."

Key features of inhibitor binding to the human mitochondrial pyruvate carrier hetero-dimer by Tavoulari, Sotiria, Schirris, Tom J.J., Mavridou, Vasiliki, Thangaratnarajah, Chancievan, King, Martin S., Jones, Daniel T.D., Ding, Shujing, Fearnley, Ian M., Kunji, Edmund R.S.

“…The mitochondrial pyruvate carrier (MPC) has emerged as a promising drug target for metabolic disorders, including non-alcoholic steatohepatitis and diabetes,…”
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Heterogeneity of tethered agonist signaling in adhesion G protein-coupled receptors by Dates, Andrew N, Jones, Daniel T D, Smith, Jeffrey S, Skiba, Meredith A, Rich, Maria F, Burruss, Maggie M, Kruse, Andrew C, Blacklow, Stephen C

“…Adhesion G protein-coupled receptor (aGPCR) signaling influences development and homeostasis in a wide range of tissues. In the current model for aGPCR…”
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Tethered agonist activated ADGRF1 structure and signalling analysis reveal basis for G protein coupling by Jones, Daniel T. D., Dates, Andrew N., Rawson, Shaun D., Burruss, Maggie M., Lipper, Colin H., Blacklow, Stephen C.

“…Adhesion G Protein Coupled Receptors (aGPCRs) have evolved an activation mechanism to translate extracellular force into liberation of a tethered agonist (TA)…”
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