Search Results - "Jones, D. Holstead"
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Regulation of cancer cell migration and bone metastasis by RANKL
Published in Nature (30-03-2006)“…Bone metastases are a frequent complication of many cancers that result in severe disease burden and pain. Since the late nineteenth century, it has been…”
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Journal Article -
2
Role of RANKL and RANK in bone loss and arthritis
Published in Annals of the rheumatic diseases (01-11-2002)“…The tumour necrosis factor family molecule RANKL (RANKL, TRANCE, ODF) and its receptor RANK are key regulators of bone remodelling and regulate T…”
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Journal Article Conference Proceeding -
3
Na,K-ATPase from Mice Lacking the γ Subunit (FXYD2) Exhibits Altered Na+ Affinity and Decreased Thermal Stability
Published in The Journal of biological chemistry (13-05-2005)“…The γ subunit of the Na,K-ATPase, a 7-kDa single-span membrane protein, is a member of the FXYD gene family. Several FXYD proteins have been shown to bind to…”
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Journal Article -
4
Bone Metastasis Can osteoclasts be excluded? (Reply)
Published in Nature (London) (22-02-2007)“…Martin and Mundy emphasize the crucial role played by osteoclasts in the metastasis of many tumour types to bone. Our intention was not to question the…”
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Journal Article -
5
Embryonic Expression of the Putative γ Subunit of the Sodium Pump Is Required for Acquisition of Fluid Transport Capacity during Mouse Blastocyst Development
Published in The Journal of cell biology (15-12-1997)“…The sodium/potassium pump, Na+, K+-ATPase, is generally understood to function as a heterodimer of two subunits, a catalytic α subunit and a noncatalytic,…”
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Journal Article -
6
Expression and role of the sodium,potassium-ATPase gamma subunit in mouse embryogenesis
Published 01-01-2000“…The Na+,K+-ATPase is generally understood to function as a heterodimer of two subunits, a catalytic α subunit and a noncatalytic, glycosylated β subunit. The…”
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Dissertation -
7
Bone Metastasis Can osteoclasts be excluded?
Published in Nature (London) (22-02-2007)“…Arising from: D. H. Jones et al. Nature 440, 692-696 (2006); Jones et al. replyThe RANK/RANKL signalling mechanism is the final common pathway of osteoclast…”
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Journal Article -
8
Role of RANKL and RANK in bone loss and arthritis
Published in Annals of the rheumatic diseases (01-11-2002)Get full text
Journal Article -
9
Na,K-ATPase from Mice Lacking the γ Subunit (FXYD2) Exhibits Altered Na+ Affinity and Decreased Thermal Stability
Published in The Journal of biological chemistry (13-05-2005)“…The γ subunit of the Na,K-ATPase, a 7-kDa single-span membrane protein, is a member of the FXYD gene family. Several FXYD proteins have been shown to bind to…”
Get full text
Journal Article -
10
Can osteoclasts be excluded? (Reply)
Published in Nature (London) (21-02-2007)Get full text
Journal Article -
11
Differential Involvement of Na+,K+-ATPase Isozymes in Preimplantation Development of the Mouse
Published in Developmental biology (15-06-2000)“…Na+,K+-ATPase plays an essential role in mammalian blastocoel formation (cavitation) by driving trans-epithelial sodium transport. Previously, the α1 and β1…”
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Journal Article -
12
Regulation of cancer cell migration and bone metastasis by RANKL
Published in Nature (30-03-2006)“…Bone metastases are a frequent complication of many cancers that result in severe disease burden and pain. Since the late nineteenth century, it has been…”
Get full text
Journal Article -
13
The mouse Na+-K+-ATPase gamma-subunit gene (Fxyd2) encodes three developmentally regulated transcripts
Published in Physiological genomics (28-08-2001)“…The Na(+)-K(+)-ATPase is understood to function as a hetero-oligomer of alpha- and beta-subunits, but a third subunit, gamma, has been proposed to influence…”
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Journal Article -
14
The mouse Na+-K+-ATPase {gamma}-subunit gene (Fxyd2) encodes three developmentally regulated transcripts
Published in Physiological genomics (28-08-2001)“…1 Departments of Physiology, Obstetrics and Gynaecology, and Paediatrics, University of Western Ontario, London N6A 5C1, and Child Health Research Institute,…”
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Journal Article -
15
Contributions of Na+/H+ exchanger isoforms to preimplantation development of the mouse
Published in Molecular reproduction and development (01-06-1998)“…Previous work provided evidence of Na+/H+ exchanger activity in the apical domain of mouse trophectodermal plasma membranes that provides a route for entry of…”
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Journal Article -
16
Multiple members of the connexin gene family participate in preimplantation development of the mouse
Published in Developmental genetics (1996)“…The connexin gene family, of which there are at least 12 members in rodents, encodes the protein subunits of intercellular membrane channels (gap junction…”
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Journal Article