Search Results - "Jones, Christopher J."

Bacterial Extracellular Polysaccharides in Biofilm Formation and Function by Limoli, Dominique H, Jones, Christopher J, Wozniak, Daniel J

“…Microbes produce a biofilm matrix consisting of proteins, extracellular DNA, and polysaccharides that is integral in the formation of bacterial communities…”
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ChIP-Seq and RNA-Seq reveal an AmrZ-mediated mechanism for cyclic di-GMP synthesis and biofilm development by Pseudomonas aeruginosa by Jones, Christopher J, Newsom, David, Kelly, Benjamin, Irie, Yasuhiko, Jennings, Laura K, Xu, Binjie, Limoli, Dominique H, Harrison, Joe J, Parsek, Matthew R, White, Peter, Wozniak, Daniel J

“…The transcription factor AmrZ regulates genes important for P. aeruginosa virulence, including type IV pili, extracellular polysaccharides, and the flagellum;…”
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Nucleotide binding by the widespread high-affinity cyclic di-GMP receptor MshEN domain by Wang, Yu-Chuan, Chin, Ko-Hsin, Tu, Zhi-Le, He, Jin, Jones, Christopher J., Sanchez, David Zamorano, Yildiz, Fitnat H., Galperin, Michael Y., Chou, Shan-Ho

“…C-di-GMP is a bacterial second messenger regulating various cellular functions. Many bacteria contain c-di-GMP-metabolizing enzymes but lack known c-di-GMP…”
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Surface texture limits transfer of S. aureus, T4 bacteriophage, influenza B virus and human coronavirus by Liu, Qi, Brookbank, Lindsey, Ho, Angela, Coffey, Jenna, Brennan, Anthony B, Jones, Christopher J

“…Spread of pathogens on contaminated surfaces plays a key role in disease transmission. Surface technologies that control pathogen transfer can help control…”
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C-di-GMP Regulates Motile to Sessile Transition by Modulating MshA Pili Biogenesis and Near-Surface Motility Behavior in Vibrio cholerae by Jones, Christopher J, Utada, Andrew, Davis, Kimberly R, Thongsomboon, Wiriya, Zamorano Sanchez, David, Banakar, Vinita, Cegelski, Lynette, Wong, Gerard C L, Yildiz, Fitnat H

“…In many bacteria, including Vibrio cholerae, cyclic dimeric guanosine monophosphate (c-di-GMP) controls the motile to biofilm life style switch. Yet, little is…”
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Systematic Identification of Cyclic-di-GMP Binding Proteins in Vibrio cholerae Reveals a Novel Class of Cyclic-di-GMP-Binding ATPases Associated with Type II Secretion Systems by Roelofs, Kevin G, Jones, Christopher J, Helman, Sarah R, Shang, Xiaoran, Orr, Mona W, Goodson, Jonathan R, Galperin, Michael Y, Yildiz, Fitnat H, Lee, Vincent T

“…Cyclic-di-GMP (c-di-GMP) is a ubiquitous bacterial signaling molecule that regulates a variety of complex processes through a diverse set of c-di-GMP receptor…”
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AmrZ Modulates Pseudomonas aeruginosa Biofilm Architecture by Directly Repressing Transcription of the psl Operon by Jones, Christopher J, Ryder, Cynthia R, Mann, Ethan E, Wozniak, Daniel J

“…Pseudomonas aeruginosa strains recovered from chronic pulmonary infections in cystic fibrosis patients are frequently mucoid. Such strains express elevated…”
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A representation of a Tuawhenua worldview guides environmental conservation by Timoti, Puke, Lyver, Philip O'B, Matamua, Rangi, Jones, Christopher J., Tahi, Brenda L.

“…Indigenous peoples and local communities interact with approximately two-thirds of the world’s land area through their worldviews and customary tenure regimes…”
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Polymyxin B resistance and biofilm formation in Vibrio cholerae are controlled by the response regulator CarR by Bilecen, Kivanc, Fong, Jiunn C N, Cheng, Andrew, Jones, Christopher J, Zamorano-Sánchez, David, Yildiz, Fitnat H

“…Two-component systems play important roles in the physiology of many bacterial pathogens. Vibrio cholerae's CarRS two-component regulatory system negatively…”
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Bilayers as Phase Transfer Agents for Nanocrystals Prepared in Nonpolar Solvents by Prakash, Arjun, Zhu, Huiguang, Jones, Christopher J, Benoit, Denise N, Ellsworth, Adam Z, Bryant, Erika L, Colvin, Vicki L

“…The effective water dispersion of highly uniform nanoparticles synthesized in organic solvents is a major issue for their broad applications. In an effort to…”
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Characterization and Optimization of the Fluorescence of Nanoscale Iron Oxide/Quantum Dot Complexes by Cho, Minjung, Contreras, Elizabeth Q, Lee, Seung Soo, Jones, Christopher J, Jang, Wonhee, Colvin, Vicki L

“…In this paper, nanoscale iron oxide/quantum dot (QD) complexes were formed in an efficient and versatile reaction that relied on the nucleation of…”
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Tumor-environment biomimetics delay peritoneal metastasis formation by deceiving and redirecting disseminated cancer cells by De Vlieghere, Elly, Gremonprez, Félix, Verset, Laurine, Mariën, Lore, Jones, Christopher J, De Craene, Bram, Berx, Geert, Descamps, Benedicte, Vanhove, Christian, Remon, Jean-Paul, Ceelen, Wim, Demetter, Pieter, Bracke, Marc, De Geest, Bruno G, De Wever, Olivier

“…Abstract Peritoneal metastasis is life threatening and is the result of an extensive communication between disseminated cancer cells, mesothelial cells and…”
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Heparin Characterization: Challenges and Solutions by Jones, Christopher J, Beni, Szabolcs, Limtiaco, John F.K, Langeslay, Derek J, Larive, Cynthia K

“…Although heparin is an important and widely prescribed pharmaceutical anticoagulant, its high degree of sequence microheterogeneity and size polydispersity…”
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Neuropeptide Y gene polymorphisms confer risk of early-onset atherosclerosis by Shah, Svati H, Freedman, Neil J, Zhang, Lisheng, Crosslin, David R, Stone, David H, Haynes, Carol, Johnson, Jessica, Nelson, Sarah, Wang, Liyong, Connelly, Jessica J, Muehlbauer, Michael, Ginsburg, Geoffrey S, Crossman, David C, Jones, Christopher J H, Vance, Jeffery, Sketch, Michael H, Granger, Christopher B, Newgard, Christopher B, Gregory, Simon G, Goldschmidt-Clermont, Pascal J, Kraus, William E, Hauser, Elizabeth R

“…Neuropeptide Y (NPY) is a strong candidate gene for coronary artery disease (CAD). We have previously identified genetic linkage to familial CAD in the genomic…”
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Peakwide Mapping on Chromosome 3q13 Identifies the Kalirin Gene as a Novel Candidate Gene for Coronary Artery Disease by Wang, Liyong, Hauser, Elizabeth R., Shah, Svati H., Pericak-Vance, Margaret A., Haynes, Carol, Crosslin, David, Harris, Marco, Nelson, Sarah, Hale, A. Brent, Granger, Christopher B., Haines, Jonathan L., Jones, Christopher J.H., Crossman, David, Seo, David, Gregory, Simon G., Kraus, William E., Goldschmidt-Clermont, Pascal J., Vance, Jeffery M.

“…A susceptibility locus for coronary artery disease (CAD) has been mapped to chromosome 3q13-21 in a linkage study of early-onset CAD. We completed an…”
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Low temperature synthesis of ZnS and CdZnS shells on CdSe quantum dots by Zhu, Huiguang, Prakash, Arjun, Benoit, Denise N, Jones, Christopher J, Colvin, Vicki L

“…Methods for synthesizing quantum dots generally rely on very high temperatures to both nucleate and grow core and core-shell semiconductor nanocrystals. In…”
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Making Better Dose Decisions: Using Exposure‐Response Modeling to Integrate Efficacy Outcome of Two Phase IIb Clinical Trials of Ubrogepant for Migraine Treatment by Li, Chi‐Chung, Voss, Tiffini, Kowalski, Ken, Yang, Bei, Kleijn, Huub Jan, Jones, Christopher J., Bosch, Rolien, Michelson, David, DeAngelis, Matthew, Xu, Yang, Xie, Iris, Kothare, Prajakti A.

“…Ubrogepant (MK‐1602) is a novel, oral, calcitonin gene‐related peptide receptor antagonist in clinical development with positive phase III outcomes for acute…”
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Metyrapone Improves Endothelial Dysfunction in Patients With Treated Depression by Broadley, Andrew J.M., Korszun, Ania, Abdelaal, Eltigani, Moskvina, Valentina, Deanfield, John, Jones, Christopher J.H., Frenneaux, Michael P.

“…Metyrapone Improves Endothelial Dysfunction in Patients With Treated Depression Andrew J. M. Broadley, Ania Korszun, Eltigani Abdelaal, Valentina Moskvina,…”
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GATA2 is associated with familial early-onset coronary artery disease by Connelly, Jessica J, Wang, Tianyuan, Cox, Julie E, Haynes, Carol, Wang, Liyong, Shah, Svati H, Crosslin, David R, Hale, A Brent, Nelson, Sarah, Crossman, David C, Granger, Christopher B, Haines, Jonathan L, Jones, Christopher J H, Vance, Jeffery M, Goldschmidt-Clermont, Pascal J, Kraus, William E, Hauser, Elizabeth R, Gregory, Simon G

“…The transcription factor GATA2 plays an essential role in the establishment and maintenance of adult hematopoiesis. It is expressed in hematopoietic stem…”
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Psl Produced by Mucoid Pseudomonas aeruginosa Contributes to the Establishment of Biofilms and Immune Evasion by Jones, Christopher J, Wozniak, Daniel J

“…Despite years of research and clinical advances, chronic pulmonary infections with mucoid remain the primary concern for cystic fibrosis patients. Much of the…”
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