Search Results - "Jones, Chelsea R."
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Isobactins: O -acyl isopeptide prodrugs of teixobactin and teixobactin derivatives
Published in Chemical science (Cambridge) (16-11-2022)“…The antibiotic teixobactin is a promising drug candidate against drug-resistant pathogens, such as MRSA and VRE, but forms insoluble gels that may limit…”
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Teixobactin kills bacteria by a two-pronged attack on the cell envelope
Published in Nature (London) (11-08-2022)“…Antibiotics that use novel mechanisms are needed to combat antimicrobial resistance 1 – 3 . Teixobactin 4 represents a new class of antibiotics with a unique…”
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3
Synthesis and application of fluorescent teixobactin analogs
Published in Methods in enzymology (2022)“…Teixobactin is a promising new antibiotic that kills a spectrum of Gram-positive pathogens that are considered to be urgent threats by the CDC and the WHO…”
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4
A β-barrel-like tetramer formed by a β-hairpin derived from Aβ
Published in Chemical science (Cambridge) (20-12-2023)“…β-Hairpins formed by the β-amyloid peptide Aβ are building blocks of Aβ oligomers. Three different alignments of β-hairpins have been observed in the…”
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5
Investigation of Isobactin Analogues of Teixobactin
Published in ACS medicinal chemistry letters (11-07-2024)“…Although teixobactin is a promising antibiotic drug candidate against Gram-positive bacteria, it aggregates to form gels that may limit intravenous…”
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6
Synthesis and Stereochemical Determination of the Peptide Antibiotic Novo29
Published in Journal of organic chemistry (17-02-2023)“…This paper describes the synthesis and stereochemical determination of Novo29 (clovibactin), a new peptide antibiotic that is related to teixobactin and is…”
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7
Visualizing the mode of action and supramolecular assembly of teixobactin analogues in Bacillus subtilis
Published in Chemical science (Cambridge) (06-07-2022)“…Teixobactin has been the source of intensive study and interest as a promising antibiotic, because of its excellent activity against drug-resistant…”
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Journal Article -
8
Isobactins: -acyl isopeptide prodrugs of teixobactin and teixobactin derivatives
Published in Chemical science (Cambridge) (16-11-2022)“…The antibiotic teixobactin is a promising drug candidate against drug-resistant pathogens, such as MRSA and VRE, but forms insoluble gels that may limit…”
Get full text
Journal Article -
9
Visualizing the mode of action and supramolecular assembly of teixobactin analogues in
Published in Chemical science (Cambridge) (06-07-2022)“…Teixobactin has been the source of intensive study and interest as a promising antibiotic, because of its excellent activity against drug-resistant…”
Get full text
Journal Article