Search Results - "Jones, Carolyn J. P."

Placental endoplasmic reticulum stress in gestational diabetes: the potential for therapeutic intervention with chemical chaperones and antioxidants by Yung, Hong-wa, Alnæs-Katjavivi, Patji, Jones, Carolyn J. P., El-Bacha, Tatiana, Golic, Michaela, Staff, Anne-Cathrine, Burton, Graham J.

“…Aims/hypothesis The aim of this work was to determine whether placental endoplasmic reticulum (ER) stress may contribute to the pathophysiology of gestational…”
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‘Fetal side’ of the placenta: anatomical mis-annotation of carbon particle ‘transfer’ across the human placenta by Holder, Beth, Aplin, John D., Gomez-Lopez, Nardhy, Heazell, Alexander E. P., James, Joanna L., Jones, Carolyn J. P., Jones, Helen, Lewis, Rohan M., Mor, Gil, Roberts, Claire T., Robertson, Sarah A., Zenclussen, Ana C.

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Menstrual flow as a non-invasive source of endometrial organoids by Cindrova-Davies, Tereza, Zhao, Xiaohui, Elder, Kay, Jones, Carolyn J. P., Moffett, Ashley, Burton, Graham J., Turco, Margherita Y.

“…Assessment of the endometrium often necessitates a biopsy, which currently involves an invasive, transcervical procedure. Here, we present an alternative…”
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Preeclampsia is associated with alterations in the p53-pathway in villous trophoblast by Sharp, Andrew N, Heazell, Alexander E P, Baczyk, Dora, Dunk, Caroline E, Lacey, Helen A, Jones, Carolyn J P, Perkins, Jonathan E, Kingdom, John C P, Baker, Philip N, Crocker, Ian P

“…Preeclampsia (PE) is characterized by exaggerated apoptosis of the villous trophoblast of placental villi. Since p53 is a critical regulator of apoptosis we…”
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Heightened Pro-Inflammatory Effect of Preeclamptic Placental Microvesicles on Peripheral Blood Immune Cells in Humans by HOLDER, Beth S, TOWER, Clare L, JONES, Carolyn J. P, APLIN, John D, ABRAHAMS, Vikki M

“…Normal pregnancy is associated with the presence of circulating placental microvesicles (MVs). Increased MV shedding and altered immune activation are seen in…”
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Glycosylation at the fetomaternal interface: does the glycocode play a critical role in implantation? by Jones, Carolyn J. P, Aplin, John D

“…During pregnancy, the heavily glycosylated surfaces of the implanting blastocyst and maternal uterine epithelium interact in a highly controlled and specific…”
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Cell dynamics in human villous trophoblast by Aplin, John D, Jones, Carolyn J P

“…Abstract BACKGROUND Villous cytotrophoblast (vCTB) is a precursor cell population that supports the development of syncytiotrophoblast (vSTB), the high surface…”
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Epidermal growth factor rescues trophoblast apoptosis induced by reactive oxygen species by Moll, Sarah J, Jones, Carolyn J. P, Crocker, Ian P, Baker, Philip N, Heazell, Alexander E. P

“…Pre-eclampsia and intrauterine growth restriction are associated with increased apoptosis of placental villous trophoblast. This may result from placental…”
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Local vaginal bioelectrical impedance can predict preterm delivery in mice by Komatsu, Reina, Nakamura, Hitomi, Hosono, Takayoshi, Masuda, Tatsuo, J P Jones, Carolyn, Aplin, John D, Mimura, Kazuya, Endo, Masayuki, Kimura, Tadashi

“…Preterm birth is a serious pregnancy complication that affects neonatal mortality, morbidity and long-term neurological prognosis. Predicting spontaneous…”
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Increased Placental Cell Senescence and Oxidative Stress in Women with Pre-Eclampsia and Normotensive Post-Term Pregnancies by Scaife, Paula J, Simpson, Amy, Kurlak, Lesia O, Briggs, Louise V, Gardner, David S, Broughton Pipkin, Fiona, Jones, Carolyn J P, Mistry, Hiten D

“…Up to 11% of pregnancies extend to post-term with adverse obstetric events linked to pregnancies over 42 weeks. Oxidative stress and senescence (cells stop…”
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Identification of autophagic vacuoles and regulators of autophagy in villous trophoblast from normal term pregnancies and in fetal growth restriction by Curtis, Sophie, Jones, Carolyn J. P., Garrod, Ainslie, Hulme, Charlotte H., Heazell, Alexander E. P.

“…Fetal growth restriction (FGR) is a serious pregnancy complication associated with increased perinatal mortality and morbidity. Although the majority of cases…”
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A simple histochemical method for the identification of cytotrophoblasts in tissue sections by Jones, Carolyn JP, Whittle, Saxon C, Aplin, John D

“…Abstract A simple method for the demonstration of placental cytotrophoblast cells is described, utilising the affinity of the lectin from Bandeiraea…”
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Eutopic endometrium from women with endometriosis shows altered ultrastructure and glycosylation compared to that from healthy controls--a pilot observational study by Jones, Carolyn J P, Inuwa, Ibrahim M, Nardo, Luciano G, Litta, Pietro, Fazleabas, Asgerally T

“…Endometrial curettings from a cohort of 24 women with endometriosis were compared with matched biopsies from 14 healthy, fertile women and examined for…”
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Live birth rate in fresh and frozen embryo transfer cycles in women with endometriosis by Mohamed, Ahmed M.F, Chouliaras, Spyridon, Jones, Carolyn J.P, Nardo, Luciano G

“…Abstract Objectives To test the hypothesise that the treatment protocol used for preparation of the endometrium for frozen embryo transfer (ET) has a…”
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Environmental nanoparticles and placental research by Aplin, John D., Jones, Carolyn J. P., Jauniaux, Eric

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Evidence for the presence of air pollution nanoparticles in placental tissue cells by Liu, Norrice M., Miyashita, Lisa, Maher, Barbara A., McPhail, Graham, Jones, Carolyn J.P., Barratt, Benjamin, Thangaratinam, Shakila, Karloukovski, Vassil, Ahmed, Imad A., Aslam, Zabeada, Grigg, Jonathan

“…Inhaled particulate matter (PM) from combustion- and friction-sourced air pollution adversely affects organs distant from the lung. A putative mechanism for…”
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Evidence of oxidative stress-induced senescence in mature, post-mature and pathological human placentas by Cindrova-Davies, Tereza, Fogarty, Norah M.E., Jones, Carolyn J.P., Kingdom, John, Burton, Graham J.

“…Premature ageing has been implicated in placental dysfunction. Senescence can be activated by oxidative stress, a key intermediary in the pathophysiology of…”
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Oligosaccharide composition is similar in drusen and dense deposits in membranoproliferative glomerulonephritis type II by D'souza, Yvonne B., Jones, Carolyn J.P., Short, Colin D., Roberts, Ian S.D., Bonshek, Richard E.

“…Drusen are a feature of age-related macular degeneration (AMD). Lesions similar in appearance to drusen are also found in the fundi of patients with…”
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Endotheliochorial placental glycosylation reflects evolutionary divergence between Felidae species (Felis catus and Panthera leo) and Canidae (Canisfamiliaris) by Jones, Carolyn J.P., Aplin, John D.

“…Endotheliochorial cat (Felis catus) and lion (Panthera leo) term placentae and one 6 week placenta (term 60–63 days) from a dog (Canis familiaris) were stained…”
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A Role for Tissue Transglutaminase in Stabilization of Membrane-Cytoskeletal Particles Shed from the Human Placenta by Robinson, Nicola J, Baker, Philip N, Jones, Carolyn J. P, Aplin, John D

“…Tissue transglutaminase (TGM2; also known as TG2 or tTG) localizes to the syncytial microvillous membrane (MVM) of the human placenta, the primary interface…”
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