Sudden cardiac death: epidemiology, pathogenesis and management

Sudden cardiac death (SCD) is an unexpected sudden death due to a heart condition, that occurs within one hour of symptoms onset. SCD is a leading cause of death in western countries, and is responsible for the majority of deaths from cardiovascular disease. Moreover, SCD accounts for mortality in a...

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Bibliographic Details
Published in:	Reviews in cardiovascular medicine Vol. 22; no. 1; pp. 147 - 158
Main Authors:	Kumar, Akshay, Avishay, Dor Mordehay, Jones, Calvin Richard, Shaikh, Juber Dastagir, Kaur, Roopvir, Aljadah, Michael, Kichloo, Asim, Shiwalkar, Nimisha, Keshavamurthy, Suresh
Format:	Journal Article
Language:	English
Published:	United States IMR Press 30-03-2021
Subjects:	cardiopulmonary resuscitation extracorporeal membrane oxygenation sudden cardiac arrest sudden cardiac death transvenous and subcutaneous implantable cardioverter devices Sudden cardiac arrest Extracorporeal membrane oxygenation Transvenous and subcutaneous implantable cardioverter devices Sudden cardiac death Cardiopulmonary resuscitation
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Summary:	Sudden cardiac death (SCD) is an unexpected sudden death due to a heart condition, that occurs within one hour of symptoms onset. SCD is a leading cause of death in western countries, and is responsible for the majority of deaths from cardiovascular disease. Moreover, SCD accounts for mortality in approximately half of all coronary heart disease patients. Nevertheless, the recent advancements made in screening, prevention, treatment, and management of the underlying causes has decreased this number. In this article, we sought to review established and new modes of screening patients at risk for SCD, treatment and prevention of SCD, and the role of new technologies in the field. Further, we delineate the current epidemiologic trends and pathogenesis. In particular, we describe the advancement in molecular autopsy and genetic testing, the role of target temperature management, extracorporeal membrane oxygenation (ECMO), cardiopulmonary resuscitation (CPR), and transvenous and subcutaneous implantable cardioverter devices (ICDs).
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1
ISSN:	1530-6550 2153-8174
DOI:	10.31083/J.RCM.2021.01.207