Search Results - "Jones, Alan E"

The Impact of the Sepsis-3 Septic Shock Definition on Previously Defined Septic Shock Patients by Sterling, Sarah A., Puskarich, Michael A., Glass, Andrew F., Guirgis, Faheem, Jones, Alan E.

“…OBJECTIVE:The Third International Consensus Definitions Task Force (Sepsis-3) recently recommended changes to the definitions of sepsis. The impact of these…”
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Serial Procalcitonin Predicts Mortality in Severe Sepsis Patients: Results From the Multicenter Procalcitonin MOnitoring SEpsis (MOSES) Study by Schuetz, Philipp, Birkhahn, Robert, Sherwin, Robert, Jones, Alan E., Singer, Adam, Kline, Jeffrey A., Runyon, Michael S., Self, Wesley H., Courtney, D. Mark, Nowak, Richard M., Gaieski, David F., Ebmeyer, Stefan, Johannes, Sascha, Wiemer, Jan C., Schwabe, Andrej, Shapiro, Nathan I.

“…OBJECTIVES:To prospectively validate that the inability to decrease procalcitonin levels by more than 80% between baseline and day 4 is associated with…”
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Relationship Between Supranormal Oxygen Tension and Outcome After Resuscitation From Cardiac Arrest by HOPE KILGANNON, J, JONES, Alan E, PARRILLO, Joseph E, DELLINGER, R. Phillip, MILCAREK, Barry, HUNTER, Krystal, SHAPIRO, Nathan I, TRZECIAK, Stephen

“…Laboratory and recent clinical data suggest that hyperoxemia after resuscitation from cardiac arrest is harmful; however, it remains unclear if the risk of…”
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Arterial Blood Pressure and Neurologic Outcome After Resuscitation From Cardiac Arrest by Kilgannon, J Hope, Roberts, Brian W, Jones, Alan E, Mittal, Neil, Cohen, Evan, Mitchell, Jessica, Chansky, Michael E, Trzeciak, Stephen

“…OBJECTIVES:Guidelines for post–cardiac arrest care recommend blood pressure optimization as one component of neuroprotection. Although some retrospective…”
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Whole Blood Lactate Kinetics in Patients Undergoing Quantitative Resuscitation for Severe Sepsis and Septic Shock by Puskarich, Michael A., MD, Trzeciak, Stephen, MD, Shapiro, Nathan I., MD, Albers, Andrew B., MD, Heffner, Alan C., MD, Kline, Jeffrey A., MD, Jones, Alan E., MD

“…Abstract Background We sought to compare the association of whole-blood lactate kinetics with survival in patients with septic shock undergoing early…”
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Incidence of Contrast-Induced Nephropathy after Contrast-Enhanced Computed Tomography in the Outpatient Setting by Mitchell, Alice M, Jones, Alan E, Tumlin, James A, Kline, Jeffrey A

“…No prospective study has reported the incidence of contrast-induced nephropathy (CIN) or the associated morbidity and mortality after contrast-enhanced…”
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Proof of principle: The predisposition, infection, response, organ failure sepsis staging system by Howell, Michael D, Talmor, Daniel, Schuetz, Philipp, Hunziker, Sabina, Jones, Alan E, Shapiro, Nathan I

“…OBJECTIVE:In an effort to improve upon the traditional sepsis syndrome definitions, the predisposition, infection, response, organ dysfunction (PIRO) model was…”
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An Emergency Department Validation of the SEP-3 Sepsis and Septic Shock Definitions and Comparison With 1992 Consensus Definitions by Henning, Daniel J., MD, Puskarich, Michael A., MD, Self, Wesley H., MD, Howell, Michael D., MD, MPH, Donnino, Michael W., MD, Yealy, Donald M., MD, Jones, Alan E., MD, Shapiro, Nathan I., MD, MPH

“…Study objective The Third International Consensus Definitions Task Force (SEP-3) proposed revised criteria defining sepsis and septic shock. We seek to…”
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HDL inflammatory index correlates with and predicts severity of organ failure in patients with sepsis and septic shock by Guirgis, Faheem W, Dodani, Sunita, Leeuwenburgh, Christiaan, Moldawer, Lyle, Bowman, Jennifer, Kalynych, Colleen, Grijalva, Victor, Reddy, Srinivasa T, Jones, Alan E, Moore, Frederick A

“…High density lipoprotein (HDL) is important for defense against sepsis but becomes dysfunctional (Dys-HDL) during inflammation. We hypothesize that Dys-HDL…”
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The Surviving Sepsis Campaign Guidelines 2012: Update for Emergency Physicians by Jones, Alan E., MD, Puskarich, Michael A., MD

“…The Surviving Sepsis Campaign recently developed and published an updated version in 2012 of the international guidelines for the assessment and management of…”
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Partial pressure of arterial carbon dioxide after resuscitation from cardiac arrest and neurological outcome: A prospective multi-center protocol-directed cohort study by Hope Kilgannon, J., Hunter, Benton R., Puskarich, Michael A., Shea, Lisa, Fuller, Brian M., Jones, Christopher, Donnino, Michael, Kline, Jeffrey A., Jones, Alan E., Shapiro, Nathan I., Abella, Benjamin S., Trzeciak, Stephen, Roberts, Brian W.

“…Partial pressure of arterial carbon dioxide (PaCO2) is a regulator of cerebral blood flow after brain injury. We sought to test the association between PaCO2…”
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The association of endothelial cell signaling, severity of illness, and organ dysfunction in sepsis by Shapiro, Nathan I, Schuetz, Philipp, Yano, Kiichiro, Sorasaki, Midori, Parikh, Samir M, Jones, Alan E, Trzeciak, Stephen, Ngo, Long, Aird, William C

“…Previous reports suggest that endothelial activation is an important process in sepsis pathogenesis. We investigated the association between biomarkers of…”
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Biomarkers of endothelial cell activation in early sepsis by Skibsted, Simon, Jones, Alan E, Puskarich, Michael A, Arnold, Ryan, Sherwin, Robert, Trzeciak, Stephen, Schuetz, Philipp, Aird, William C, Shapiro, Nathan I

“…The objective of this study was to investigate the association of endothelial-related markers with organ dysfunction and in-hospital mortality to validate our…”
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Prospective external validation of the clinical effectiveness of an emergency department-based early goal-directed therapy protocol for severe sepsis and septic shock by Jones, Alan E, Focht, Anne, Horton, James M, Kline, Jeffrey A

“…To determine the clinical effectiveness of implementing early goal-directed therapy (EGDT) as a routine protocol in the emergency department (ED). Prospective…”
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Multicenter Study of Central Venous Oxygen Saturation (ScvO2 ) as a Predictor of Mortality in Patients With Sepsis by Pope, Jennifer V., MD, Jones, Alan E., MD, Gaieski, David F., MD, Arnold, Ryan C., MD, Trzeciak, Stephen, MD, MPH, Shapiro, Nathan I., MD, MPH

“…Study objective Abnormal (both low and high) central venous saturation (ScvO2 ) is associated with increased mortality in emergency department (ED) patients…”
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Procalcitonin Test in the Diagnosis of Bacteremia: A Meta-analysis by Jones, Alan E., MD, Fiechtl, James F., MD, Brown, Michael D., MD, Ballew, Jason J., MD, Kline, Jeffrey A., MD

“…Study objective We seek to evaluate the diagnostic performance of the procalcitonin test for the diagnosis of bacteremia in the emergency department (ED)…”
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Etiology of Illness in Patients with Severe Sepsis Admitted to the Hospital from the Emergency Department by Jones, Alan E., Heffner, Alan C., Horton, James M., Marchick, Michael R.

“…Background. Patients identified with sepsis in the emergency department often are treated on the basis of the presumption of infection; however, various…”
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Prognosis of emergency department patients with suspected infection and intermediate lactate levels: A systematic review by Puskarich, Michael A., MD, Illich, Benjamin M, Jones, Alan E., MD

“…Abstract Purpose Previous studies have shown a correlation between blood lactate greater than 4.0 mmol/L and mortality in patients with suspected infection in…”
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Point: Should Lactate Clearance Be Substituted for Central Venous Oxygen Saturation as Goals of Early Severe Sepsis and Septic Shock Therapy? Yes by Jones, Alan E., MD

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Lactate clearance in the acutely traumatized patient by Jones, Alan E

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