Advancements in MRI-Based Methods for Targeting Transcranial Focused Ultrasound

The overall goal of the work described in this dissertation is the development of improved magnetic resonance imaging (MRI)-based targeting methods for transcranial MR-guided focused ultrasound (MRgFUS). Transcranial MRgFUS is a mature technology with a number of neurological applications [1]. For e...

Full description

Saved in:

Bibliographic Details
Main Author:	Jonathan, Sumeeth Vijay
Format:	Dissertation
Language:	English
Published:	ProQuest Dissertations & Theses 01-01-2020
Subjects:	Biomedical engineering Brain Grammatical case Health care management Magnetic resonance imaging Medical imaging Neurosciences Patients Public health
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	The overall goal of the work described in this dissertation is the development of improved magnetic resonance imaging (MRI)-based targeting methods for transcranial MR-guided focused ultrasound (MRgFUS). Transcranial MRgFUS is a mature technology with a number of neurological applications [1]. For example, non-invasive ablative thalamotomy is an FDA-approved treatment option for patients with essential tremor [2] or tremor-dominant Parkinsonism [3]. Recent human trials have been successful for blood-brain barrier (BBB) opening [4] and neuromodulation [5–8] via low intensity FUS.
ISBN:	9798557010658