Search Results - "Jonas M. Sheehan"
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MRI contrast agent for targeting glioma: interleukin-13 labeled liposome encapsulating gadolinium-DTPA
Published in Neuro-oncology (Charlottesville, Va.) (01-05-2016)“…Detection of glioma with MRI contrast agent is limited to cases in which the blood-brain barrier (BBB) is compromised as contrast agents cannot cross the BBB…”
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Efficacy of interleukin-13 receptor–targeted liposomal doxorubicin in the intracranial brain tumor model
Published in Molecular cancer therapeutics (01-03-2009)“…Human glioblastoma tumors selectively express receptors for interleukin 13 (IL-13). In a previous study, we showed that liposomes, when conjugated with IL-13,…”
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Stereotactic radiosurgery for pituitary adenomas: an intermediate review of its safety, efficacy, and role in the neurosurgical treatment armamentarium
Published in Journal of neurosurgery (01-04-2005)“…Pituitary adenomas are very common neoplasms, constituting between 10 and 20% of all primary brain tumors. Historically, the treatment armamentarium for…”
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Neoadjuvant concurrent chemoradiation for advanced esthesioneuroblastoma: a case series and review of the literature
Published in Journal of clinical oncology (01-05-2011)Get full text
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Interleukin-13 receptor–targeted nanovesicles are a potential therapy for glioblastoma multiforme
Published in Molecular cancer therapeutics (01-12-2006)“…The difficulties associated with treatment of malignant brain tumors are well documented. For example, local infiltration of high-grade astrocytomas prevents…”
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Reflections on shunt infection
Published in Pediatric neurosurgery (01-12-2003)“…The placement and revision of ventriculoperitoneal (VP) shunts remains a mainstay in the surgical treatment of hydrocephalus. While the North American…”
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Stereotactic radiosurgery for pituitary adenomas: a review of the literature
Published in Journal of neuro-oncology (01-08-2004)“…Pituitary adenomas are very common neoplasms and represent between 10 and 20% of all primary brain tumors. Historically, the treatment armamentarium for…”
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8
Idiopathic temporal bone encephaloceles in the obese patient
Published in Otolaryngology-head and neck surgery (01-06-2007)“…Our aims were to introduce temporal bone encephalocele (TBE) to the differential diagnosis of persistent middle ear effusion, cerebrospinal fluid otorrhea, or…”
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Heavy Chain Ferritin siRNA Delivered by Cationic Liposomes Increases Sensitivity of Cancer Cells to Chemotherapeutic Agents
Published in Cancer research (Chicago, Ill.) (15-03-2011)“…Approximately half of all gliomas are resistant to chemotherapy, and new therapeutic strategies are urgently needed to treat this cancer. We hypothesized that…”
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Glioblastoma Multiforme
Published in Neurology Research International (01-01-2012)Get full text
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11
Identification and enumeration of circulating tumor cells in the cerebrospinal fluid of breast cancer patients with central nervous system metastases
Published in Oncotarget (01-10-2011)“…The number of circulating tumor cells (CTCs) in the peripheral blood of metastatic breast cancer patients is now an established prognostic marker. While the…”
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COX-2 Drives Metastatic Breast Cells from Brain Lesions into the Cerebrospinal Fluid and Systemic Circulation
Published in Cancer research (Chicago, Ill.) (01-05-2014)“…Breast cancer is among the most common malignancies that metastasize to the brain, with 15% to 20% of patients with metastatic breast cancer eventually…”
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Distinguishing grade I meningioma from higher grade meningiomas without biopsy
Published in Oncotarget (10-11-2015)“…Many meningiomas are identified by imaging and followed, with an assumption that they are WHO Grade I tumors. The purpose of our investigation is to find…”
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Pioneers in the development of neurological surgery in Auckland, New Zealand: Robertson, Wrightson, and Mackenzie
Published in Neurosurgery (01-08-2005)“…To demonstrate the development of neurosurgery in Auckland, New Zealand, which has diverse roots and was influenced by geographical, socioeconomic, and…”
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HFE polymorphisms affect survival of brain tumor patients
Published in Journal of neuro-oncology (01-03-2015)“…The HFE (high iron) protein plays a key role in the regulation of body iron. HFE polymorphisms (H63D and C282Y) are the common genetic variants in Caucasians…”
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Surgical management of brain metastases
Published in Neurosurgical focus (15-03-2007)“…Metastatic brain tumors continue to increase in incidence as patients with cancer live longer. The options for management continue to evolve as well, with…”
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Brain magnetic resonance imaging changes after sorafenib and sunitinib chemotherapy in patients with advanced renal cell and breast carcinoma: Clinical article
Published in Journal of neurosurgery (01-09-2009)“…Object The authors report novel imaging findings associated with the treatment of sorafenib (Nexavar) and sunitinib (Sutant), 2 agents used in the treatment of…”
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HFE polymorphisms influence the response to chemotherapeutic agents via induction of p16INK4A
Published in International journal of cancer (01-11-2011)“…HFE is a protein that impacts cellular iron uptake. HFE gene variants are identified as risk factors or modifiers for multiple diseases. Using HFE stably…”
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Radiosurgery for Cushing's disease after failed transsphenoidal surgery
Published in Journal of neurosurgery (01-11-2000)“…Although transsphenoidal surgery has become the standard of care for Cushing's disease, it is often unsuccessful in normalizing cortisol production. In this…”
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Detection of circulating tumor cells in the cerebrospinal fluid of a patient with a solitary metastasis from breast cancer: A case report
Published in Oncology letters (01-06-2014)“…Brain lesions identified following the diagnosis and eradication of primary cancers are often ambiguous in origin, existing as a solitary metastasis or an…”
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