Search Results - "Jonas, Katharina"

RNA-Binding Proteins as Important Regulators of Long Non-Coding RNAs in Cancer by Jonas, Katharina, Calin, George A, Pichler, Martin

“…The majority of the genome is transcribed into pieces of non-(protein) coding RNA, among which long non-coding RNAs (lncRNAs) constitute a large group of…”
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MiR-4649-5p acts as a tumor-suppressive microRNA in triple negative breast cancer by direct interaction with PIP5K1C, thereby potentiating growth-inhibitory effects of the AKT inhibitor capivasertib by Jonas, Katharina, Prinz, Felix, Ferracin, Manuela, Krajina, Katarina, Pasculli, Barbara, Deutsch, Alexander, Madl, Tobias, Rinner, Beate, Slaby, Ondrej, Klec, Christiane, Pichler, Martin

“…Background Triple negative breast cancer (TNBC) is a particularly aggressive and difficult-to-treat subtype of breast cancer that requires the development of…”
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Long-Noncoding RNA (lncRNA) in the Regulation of Hypoxia-Inducible Factor (HIF) in Cancer by Barth, Dominik A., Prinz, Felix, Teppan, Julia, Jonas, Katharina, Klec, Christiane, Pichler, Martin

“…Hypoxia is dangerous for oxygen-dependent cells, therefore, physiological adaption to cellular hypoxic conditions is essential. The transcription factor…”
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Involvement of Long Non-Coding RNAs (lncRNAs) in Tumor Angiogenesis by Teppan, Julia, Barth, Dominik A, Prinz, Felix, Jonas, Katharina, Pichler, Martin, Klec, Christiane

“…Long non-coding RNAs (lncRNAs) are defined as non-protein coding transcripts with a minimal length of 200 nucleotides. They are involved in various biological…”
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MicroRNA mimics can distort physiological microRNA effects on immune checkpoints by triggering an antiviral interferon response by Prinz, Felix, Jonas, Katharina, Balihodzic, Amar, Klec, Christiane, Reicher, Andreas, Barth, Dominik Andreas, Riedl, Jakob, Gerger, Armin, Kiesslich, Tobias, Mayr, Christian, Rinner, Beate, Kargl, Julia, Pichler, Martin

“…The microRNA-200 family has wide-ranging regulatory functions in cancer development and progression. Above all, it is strongly associated with the…”
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MiR-4646-5p Acts as a Tumor-Suppressive Factor in Triple Negative Breast Cancer and Targets the Cholesterol Transport Protein GRAMD1B by Jonas, Katharina, Prinz, Felix, Ferracin, Manuela, Krajina, Katarina, Deutsch, Alexander, Madl, Tobias, Rinner, Beate, Slaby, Ondrej, Klec, Christiane, Pichler, Martin

“…MicroRNAs (miRNAs) are crucial post-transcriptional regulators of gene expression, and their deregulation contributes to many aspects of cancer development and…”
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MicroRNAs as regulators of tumor metabolism by Ruggieri, Francesca, Jonas, Katharina, Ferracin, Manuela, Dengler, Michael, Jӓger, Vanessa, Pichler, Martin

“…Cancer cells reprogram their metabolism to support their growth. Since the discovery of the Warburg effect, several other metabolic alterations and metabolites…”
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ALYREF, a novel factor involved in breast carcinogenesis, acts through transcriptional and post-transcriptional mechanisms selectively regulating the short NEAT1 isoform by Klec, Christiane, Knutsen, Erik, Schwarzenbacher, Daniela, Jonas, Katharina, Pasculli, Barbara, Heitzer, Ellen, Rinner, Beate, Krajina, Katarina, Prinz, Felix, Gottschalk, Benjamin, Ulz, Peter, Deutsch, Alexander, Prokesch, Andreas, Jahn, Stephan W., Lellahi, S. Mohammad, Perander, Maria, Barbano, Raffaela, Graier, Wolfgang F., Parrella, Paola, Calin, George Adrian, Pichler, Martin

“…The RNA-binding protein ALYREF (THOC4) is involved in transcriptional regulation and nuclear mRNA export, though its role and molecular mode of action in…”
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E2F transcription factor-1 modulates expression of glutamine metabolic genes in mouse embryonic fibroblasts and uterine sarcoma cells by Huber, Katharina, Giralt, Albert, Dreos, René, Michenthaler, Helene, Geller, Sarah, Barquissau, Valentin, Ziegler, Dorian V., Tavernari, Daniele, Gallart-Ayala, Hector, Krajina, Katarina, Jonas, Katharina, Ciriello, Giovanni, Ivanisevic, Julijana, Prokesch, Andreas, Pichler, Martin, Fajas, Lluis

“…Metabolic reprogramming is considered as a hallmark of cancer and is clinically exploited as a novel target for therapy. The E2F transcription factor-1 (E2F1)…”
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MiR-200c-3p Modulates Cisplatin Resistance in Biliary Tract Cancer by ZEB1-Independent Mechanisms by Posch, Florian, Prinz, Felix, Balihodzic, Amar, Mayr, Christian, Kiesslich, Tobias, Klec, Christiane, Jonas, Katharina, Barth, Dominik A., Riedl, Jakob M., Gerger, Armin, Pichler, Martin

“…Biliary tract cancer is a major global health issue in cancer-related mortality. Therapeutic options are limited, and cisplatin-based treatment schedules…”
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Tumor Suppressor miR-27a-5p and Its Significance for Breast Cancer by Parrella, Paola, Barbano, Raffaela, Jonas, Katharina, Fontana, Andrea, Barile, Serena, Rendina, Michelina, lo Mele, Antonio, Prencipe, Giuseppina, Ciuffreda, Luigi, Morritti, Maria Grazia, Valori, Vanna Maria, Graziano, Paolo, Maiello, Evaristo, Copetti, Massimiliano, Pichler, Martin, Pasculli, Barbara

“…Background: MicroRNAs are well established as master regulators of carcinogenesis and potential biomarkers in breast cancer (BC). In a preliminary effort, we…”
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