Search Results - "Jon, Sangyong"

Hyaluronic acid–bilirubin nanomedicine for targeted modulation of dysregulated intestinal barrier, microbiome and immune responses in colitis by Lee, Yonghyun, Sugihara, Kohei, Gillilland, Merritt G., Jon, Sangyong, Kamada, Nobuhiko, Moon, James J.

“…While conventional approaches for inflammatory bowel diseases mainly focus on suppressing hyperactive immune responses, it remains unclear how to address…”
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A Drug-Loaded Aptamer−Gold Nanoparticle Bioconjugate for Combined CT Imaging and Therapy of Prostate Cancer by Kim, Dongkyu, Jeong, Yong Yeon, Jon, Sangyong

“…Computed tomography (CT) is one of the most useful diagnostic tools among commonly used biomedical imaging techniques, which also include magnetic resonance…”
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Targeting strategies for multifunctional nanoparticles in cancer imaging and therapy by Yu, Mi Kyung, Park, Jinho, Jon, Sangyong

“…Nanomaterials offer new opportunities for cancer diagnosis and treatment. Multifunctional nanoparticles harboring various functions including targeting,…”
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Bilirubin Nanoparticles as a Nanomedicine for Anti-inflammation Therapy by Lee, Yonghyun, Kim, Hyungjun, Kang, Sukmo, Lee, Jinju, Park, Jinho, Jon, Sangyong

“…Despite the high potency of bilirubin as an endogenous anti‐inflammatory compound, its clinical translation has been hampered because of its insolubility in…”
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Sequential and Timely Combination of a Cancer Nanovaccine with Immune Checkpoint Blockade Effectively Inhibits Tumor Growth and Relapse by Kim, Yujin, Kang, Sukmo, Shin, Hocheol, Kim, Taewoo, Yu, Byeongjun, Kim, Jinjoo, Yoo, Dohyun, Jon, Sangyong

“…We describe a small lipid nanoparticle (SLNP)‐based nanovaccine platform and a new combination treatment regimen. Tumor antigen‐displaying, CpG…”
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Liposomal Delivery of an Immunostimulatory CpG Induces Robust Antitumor Immunity and Long‐Term Immune Memory by Reprogramming Tumor‐Associated Macrophages by Kim, Yujin, Lee, Seojung, Jon, Sangyong

“…Tumor‐associated macrophages (TAMs)—representative immune‐suppressive cells in the tumor microenvironment (TME)—are known to promote tumor progression and…”
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Liposomal Delivery of an Immunostimulatory CpG Induces Robust Antitumor Immunity and Long‐Term Immune Memory by Reprogramming Tumor‐Associated Macrophages (Adv. Healthcare Mater. 6/2024) by Kim, Yujin, Lee, Seojung, Jon, Sangyong

“…Liposome‐based Nanomedicine In article 2300549, Yujin Kim, Seojung Lee, and Sangyong Jon have developed a liposome‐based nanomedicine that can polarize…”
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Bioengineered Bacterial Outer Membrane Vesicles as Cell-Specific Drug-Delivery Vehicles for Cancer Therapy by Gujrati, Vipul, Kim, Sunghyun, Kim, Sang-Hyun, Min, Jung Joon, Choy, Hyon E, Kim, Sun Chang, Jon, Sangyong

“…Advances in genetic engineering tools have contributed to the development of strategies for utilizing biologically derived vesicles as nanomedicines for…”
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Bilirubin nanoparticle preconditioning protects against hepatic ischemia-reperfusion injury by Kim, Jin Yong, Lee, Dong Yun, Kang, Sukmo, Miao, Wenjun, Kim, Hyungjun, Lee, Yonghyun, Jon, Sangyong

“…Abstract Hepatic ischemia-reperfusion injury (IRI) remains a major concern in liver transplantation and resection, despite continuing efforts to prevent it…”
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Parallel microfluidic synthesis of size-tunable polymeric nanoparticles using 3D flow focusing towards in vivo study by Lim, Jong-Min, PhD, Bertrand, Nicolas, PhD, Valencia, Pedro M., PhD, Rhee, Minsoung, PhD, Langer, Robert, ScD, Jon, Sangyong, PhD, Farokhzad, Omid C., MD, Karnik, Rohit, PhD

“…Abstract Microfluidic synthesis of nanoparticles (NPs) can enhance the controllability and reproducibility in physicochemical properties of NPs compared to…”
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An Aptamer-Doxorubicin Physical Conjugate as a Novel Targeted Drug-Delivery Platform by Bagalkot, Vaishali, Farokhzad, Omid C., Langer, Robert, Jon, Sangyong

“…Trojan aptamer: A novel strategy for targeted drug delivery to cancer cells was developed through the formation of a physical conjugate (see scheme) between…”
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Biotinylated Bilirubin Nanoparticles as a Tumor Microenvironment‐Responsive Drug Delivery System for Targeted Cancer Therapy by Lee, Yonghyun, Lee, Soyoung, Jon, Sangyong

“…The tumor microenvironment (TME) plays a crucial role in tumorigenesis and cancer cell metastasis. Accordingly, a drug‐delivery system (DDS) that is capable of…”
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Magnetic nanoparticle-based theranostics by Xie, Jin, Jon, Sangyong

“…This theme issue provides a timely collection of studies on magnetic nanoparticle-based imaging, bio-sensing, therapy and/or their combinations…”
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Longitudinal Magnetic Resonance Imaging with ROS‐Responsive Bilirubin Nanoparticles Enables Monitoring of Nonalcoholic Steatohepatitis Progression to Cirrhosis by Jung, Wonsik, Asaduddin, Muhammad, Keum, Hyeongseop, Son, Youngju, Yoo, Dohyun, Kim, Dohyeon, Lee, Seojung, Lee, Dong Yun, Roh, Jin, Park, Sung‐Hong, Jon, Sangyong

“…Despite the vital importance of monitoring the progression of nonalcoholic fatty liver disease (NAFLD) and its progressive form, nonalcoholic steatohepatitis…”
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Ultrasensitive Electrochemical Detection of miRNA-21 Using a Zinc Finger Protein Specific to DNA–RNA Hybrids by Fang, Chiew San, Kim, Kwang-sun, Yu, Byeongjun, Jon, Sangyong, Kim, Moon-Soo, Yang, Haesik

“…Both high sensitivity and high specificity are crucial for detection of miRNAs that have emerged as important clinical biomarkers. Just Another Zinc finger…”
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Glycocalyx‐Mimicking Nanoparticles with Differential Organ Selectivity for Drug Delivery and Therapy (Adv. Mater. 27/2024) by Kim, Dohyeon, Whang, Chang‐Hee, Hong, Jungwoo, Prayogo, Monica Celine, Jung, Wonsik, Lee, Seojung, Shin, Hocheol, Kim, Yujin, Yu, Jiyoung, Kim, Min Joong, Kim, Kyunggon, Lee, Hee‐Seung, Jon, Sangyong

“…Drug Delivery In article number 2311283, Hee‐Seung Lee, Sangyong Jon, and co‐workers have develop an organ‐selective drug delivery platform based on a library…”
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Tubulin‐Based Nanotubes as Delivery Platform for Microtubule‐Targeting Agents by Kim, Jinjoo, Lee, Juncheol, Lee, Jimin, Keum, Hyeongseop, Kim, Yumi, Kim, Yujin, Yu, Byeongjun, Lee, Sang Yeop, Tanaka, Junichi, Jon, Sangyong, Choi, Myung Chul

“…Tubulin‐based nanotubes (TNTs) to deliver microtubule‐targeting agents (MTAs) for clinical oncology are reported. Three MTAs, docetaxel (DTX), laulimalide…”
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Black Pigment Gallstone Inspired Platinum‐Chelated Bilirubin Nanoparticles for Combined Photoacoustic Imaging and Photothermal Therapy of Cancers by Lee, Dong Yun, Kim, Jin Yong, Lee, Yonghyun, Lee, Soyoung, Miao, Wenjun, Kim, Hyeon Sik, Min, Jung‐Joon, Jon, Sangyong

“…Bilirubin (BR), a bile pigment that exerts potent antioxidant and anti‐inflammatory effects, is also a major constituent of black pigment gallstones found in…”
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Quantum Dot−Aptamer Conjugates for Synchronous Cancer Imaging, Therapy, and Sensing of Drug Delivery Based on Bi-Fluorescence Resonance Energy Transfer by Bagalkot, Vaishali, Zhang, Liangfang, Levy-Nissenbaum, Etgar, Jon, Sangyong, Kantoff, Philip W, Langer, Robert, Farokhzad, Omid C

“…We report a novel quantum dot (QD)−aptamer(Apt)−doxorubicin (Dox) conjugate [QD−Apt(Dox)] as a targeted cancer imaging, therapy, and sensing system. By…”
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Antibiofouling Polymer-Coated Superparamagnetic Iron Oxide Nanoparticles as Potential Magnetic Resonance Contrast Agents for in Vivo Cancer Imaging by Lee, Haerim, Lee, Eunhye, Kim, Do Kyung, Jang, Nam Kyu, Jeong, Yong Yeon, Jon, Sangyong

“…We report the fabrication and characterization of antifouling polymer-coated magnetic nanoparticles as nanoprobes for magnetic resonance (MR) contrast agents…”
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