Search Results - "Joly, Kristin M."
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Intestinal inhibition of the Na+/H+ exchanger 3 prevents cardiorenal damage in rats and inhibits Na+ uptake in humans
Published in Science translational medicine (12-03-2014)“…The management of sodium intake is clinically important in many disease states including heart failure, kidney disease, and hypertension. Tenapanor is an…”
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2
Age exacerbates chronic catecholamine-induced impairments in contractile reserve in the rat
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01-08-2011)“…Contractile reserve decreases with advancing age and chronic isoproterenol (ISO) administration is a well-characterized model of cardiac hypertrophy known to…”
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Effect of diet on the progression of diabetic nephropathy in db/db mice
Published in The FASEB journal (01-04-2013)“…Abstract only Diabetic nephropathy (DN) is the leading cause of end stage renal disease. Severity of diabetes and its complications are influenced by dietary…”
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Dose‐dependent effects of losartan and salt‐sensitivity of diabetic nephropathy in ZSF1 rats
Published in The FASEB journal (01-04-2013)“…Abstract only Diabetic nephropathy (DN) is the leading cause of end stage renal disease. Renal complications of diabetes are influenced by hypertensive…”
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Pan‐Histone deacetylase inhibition (HDACi) prevents heart failure with preserved ejection fraction (HFpEF) and cardiac fibrosis in high‐salt (HS) fed Dahl S rats (DS)
Published in The FASEB journal (01-04-2010)“…Chronic arterial hypertension (HYP) elicits cardiac hypertrophy and ultimately HFpEF, and >50% of patients diagnosed with heart failure have HFpEF. DS rats…”
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Histone deacetylase inhibition (HDACi) attenuates catecholamine‐induced impairments in contractile reserve
Published in The FASEB journal (01-04-2010)“…Chronic catecholamine excess is a well‐characterized model of cardiac hypertrophy and dysfunction. We recently demonstrated adult, non‐senescent rats have…”
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Histone deacetylase inhibition augments thyroid hormone (T3)‐induced increases in cardiac performance in hypothyroid rats
Published in The FASEB journal (01-04-2009)“…Abstract only Co‐administration of an HDAC inhibitor (HDACi) potentiates T 3 ‐induced α‐MyHC expression in hypothyroid rats. We investigated the effects of a…”
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