Search Results - "Joly, Kristin"

Intestinal inhibition of the Na+/H+ exchanger 3 prevents cardiorenal damage in rats and inhibits Na+ uptake in humans by Spencer, Andrew G, Labonte, Eric D, Rosenbaum, David P, Plato, Craig F, Carreras, Christopher W, Leadbetter, Michael R, Kozuka, Kenji, Kohler, Jill, Koo-McCoy, Samantha, He, Limin, Bell, Noah, Tabora, Jocelyn, Joly, Kristin M, Navre, Marc, Jacobs, Jeffrey W, Charmot, Dominique

“…The management of sodium intake is clinically important in many disease states including heart failure, kidney disease, and hypertension. Tenapanor is an…”
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Age exacerbates chronic catecholamine-induced impairments in contractile reserve in the rat by Liles, John T, Ida, Kevin K, Joly, Kristin M, Chapo, Joseph, Plato, Craig F

“…Contractile reserve decreases with advancing age and chronic isoproterenol (ISO) administration is a well-characterized model of cardiac hypertrophy known to…”
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Optimization of LpxC Inhibitors for Antibacterial Activity and Cardiovascular Safety by Cohen, Frederick, Aggen, James B., Andrews, Logan D., Assar, Zahra, Boggs, Jen, Choi, Taylor, Dozzo, Paola, Easterday, Ashton N., Haglund, Cat M., Hildebrandt, Darin J., Holt, Melissa C., Joly, Kristin, Jubb, Adrian, Kamal, Zeeshan, Kane, Timothy R., Konradi, Andrei W., Krause, Kevin M., Linsell, Martin S., Machajewski, Timothy D., Miroshnikova, Olga, Moser, Heinz E., Nieto, Vincent, Phan, Thu, Plato, Craig, Serio, Alisa W., Seroogy, Julie, Shakhmin, Anton, Stein, Adam J., Sun, Alex D., Sviridov, Serguei, Wang, Zhan, Wlasichuk, Kenneth, Yang, Wen, Zhou, Xiaoming, Zhu, Hai, Cirz, Ryan T.

“…UDP‐3‐O‐(R‐3‐hydroxymyristoyl)‐N‐acetylglucosamine deacetylase (LpxC) is a Zn2+ deacetylase that is essential for the survival of most pathogenic Gram‐negative…”
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Effect of diet on the progression of diabetic nephropathy in db/db mice by Kandlikar, Sachin S, Joly, Kristin M, Horn, Todd R, Glascock, Chris G, Plato, Craig F

“…Abstract only Diabetic nephropathy (DN) is the leading cause of end stage renal disease. Severity of diabetes and its complications are influenced by dietary…”
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Dose‐dependent effects of losartan and salt‐sensitivity of diabetic nephropathy in ZSF1 rats by Plato, Craig F., Silva, Stacia L, Joly, Kristin M, Horn, Todd R

“…Abstract only Diabetic nephropathy (DN) is the leading cause of end stage renal disease. Renal complications of diabetes are influenced by hypertensive…”
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Selonsertib Enhances Kidney Protection Beyond Standard of Care in a Hypertensive, Secondary Glomerulosclerosis CKD Model by Badal, Shawn S, Al Tuhaifi, Tareq, Yu, Ya-Fen, Lopez, David, Plato, Craig T, Joly, Kristin, Breckenridge, David G, Yang, Hai-Chun, Liles, John T, Fogo, Agnes B

“…Despite widespread use of renin-aldosterone-angiotensin system inhibitors and the benefits of lowering glomerular pressure in patients with CKD, there remains…”
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A high-performance liquid chromatography assay for quantification of cardiac myosin heavy chain isoform protein expression by Lemon, Douglas D., Papst, Philip J., Joly, Kristin, Plato, Craig F., McKinsey, Timothy A.

“…Stress signaling in the myocardium results in enhanced expression of fetal β-myosin heavy chain (β-MyHC) and reduced expression of adult α-myosin heavy chain…”
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Pan‐Histone deacetylase inhibition (HDACi) prevents heart failure with preserved ejection fraction (HFpEF) and cardiac fibrosis in high‐salt (HS) fed Dahl S rats (DS) by Plato, Craig F, Perry, Amy M, Joly, Kristin M, Glascock, Christopher, Cavasin, Maria A

“…Chronic arterial hypertension (HYP) elicits cardiac hypertrophy and ultimately HFpEF, and >50% of patients diagnosed with heart failure have HFpEF. DS rats…”
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Histone deacetylase inhibition (HDACi) attenuates catecholamine‐induced impairments in contractile reserve by Liles, John Thomas, Joly, Kristin M., Ida, Kevin K, Chapo, Joseph, Plato, Craig F.

“…Chronic catecholamine excess is a well‐characterized model of cardiac hypertrophy and dysfunction. We recently demonstrated adult, non‐senescent rats have…”
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Age exacerbates chronic catecholamine‐induced impairments in contractile reserve by Liles, John Thomas, Ida, Kevin, Joly, Kristin, Chapo, Joseph, Peng, Yanyu, Plato, Craig F

“…Abstract only Heart failure is more prevalent and impaired contractile reserve develops with advancing age. This study evaluated whether adult, non‐senescent…”
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Histone deacetylase inhibition augments thyroid hormone (T3)‐induced increases in cardiac performance in hypothyroid rats by Plato, Craig F, Joly, Kristin M, Glascock, Chris, Pitts, Kelly R

“…Abstract only Co‐administration of an HDAC inhibitor (HDACi) potentiates T 3 ‐induced α‐MyHC expression in hypothyroid rats. We investigated the effects of a…”
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