Search Results - "Jolicœur, Mario"

A dynamic metabolic flux analysis of ABE (acetone‐butanol‐ethanol) fermentation by Clostridium acetobutylicum ATCC 824, with riboflavin as a by‐product by Zhao, Xinhe, Kasbi, Mayssa, Chen, Jingkui, Peres, Sabine, Jolicoeur, Mario

“…The present study reveals that supplementing sodium acetate (NaAc) strongly stimulates riboflavin production in acetone‐butanol‐ethanol (ABE) fermentation by…”
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A Single Dynamic Metabolic Model Can Describe mAb Producing CHO Cell Batch and Fed-Batch Cultures on Different Culture Media by Robitaille, Julien, Chen, Jingkui, Jolicoeur, Mario

“…CHO cell culture high productivity relies on optimized culture medium management under fed-batch or perfused chemostat strategies enabling high cell densities…”
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Metabolic therapies inhibit tumor growth in vivo and in silico by da Veiga Moreira, Jorgelindo, Hamraz, Minoo, Abolhassani, Mohammad, Schwartz, Laurent, Jolicœur, Mario, Peres, Sabine

“…In the recent years, cancer research succeeded with sensitive detection methods, targeted drug delivery systems, and the identification of a large set of genes…”
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How important is thermodynamics for identifying elementary flux modes? by Peres, Sabine, Jolicœur, Mario, Moulin, Cécile, Dague, Philippe, Schuster, Stefan

“…We present a method for computing thermodynamically feasible elementary flux modes (tEFMs) using equilibrium constants without need of internal metabolite…”
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Analyzing clonal variation of monoclonal antibody-producing CHO cell lines using an in silico metabolomic platform by Ghorbaniaghdam, Atefeh, Chen, Jingkui, Henry, Olivier, Jolicoeur, Mario

“…Monoclonal antibody producing Chinese hamster ovary (CHO) cells have been shown to undergo metabolic changes when engineered to produce high titers of…”
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Fine-tuning mitochondrial activity in Yarrowia lipolytica for citrate overproduction by da Veiga Moreira, Jorgelindo, Jolicoeur, Mario, Schwartz, Laurent, Peres, Sabine

“…Yarrowia lipolytica is a non-conventional yeast with promising industrial potentials for lipids and citrate production. It is also widely used for studying…”
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Targeting Mitochondrial Singlet Oxygen Dynamics Offers New Perspectives for Effective Metabolic Therapies of Cancer by da Veiga Moreira, Jorgelindo, Schwartz, Laurent, Jolicoeur, Mario

“…The occurrence of mitochondrial respiration has allowed evolution toward more complex and advanced life forms. However, its dysfunction is now also seen as the…”
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Physical forces modulate cell differentiation and proliferation processes by Schwartz, Laurent, Veiga Moreira, Jorgelindo, Jolicoeur, Mario

“…Currently, the predominant hypothesis explains cellular differentiation and behaviour as an essentially genetically driven intracellular process, suggesting a…”
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Combining lipoic acid to methylene blue reduces the Warburg effect in CHO cells: From TCA cycle activation to enhancing monoclonal antibody production by Montégut, Léa, Martínez-Basilio, Pablo César, da Veiga Moreira, Jorgelindo, Schwartz, Laurent, Jolicoeur, Mario

“…The Warburg effect, a hallmark of cancer, has recently been identified as a metabolic limitation of Chinese Hamster Ovary (CHO) cells, the primary platform for…”
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A kinetic metabolic study of lipid production in Chlorella protothecoides under heterotrophic condition by Ren, Xiaojie, Deschênes, Jean-Sébastien, Tremblay, Réjean, Peres, Sabine, Jolicoeur, Mario

“…Microalgae have been proposed as potential platform to produce lipid-derived products, such as biofuels. Knowledge on the intracellular carbon flow…”
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Modeling cell behavior: moving beyond intuition by Jolicoeur, Mario

“…In the context of the launching of this new journal, we propose a forum to the community of researchers interested and involved in, or even simply questioning…”
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Metabolomics and in-silico analysis reveal critical energy deregulations in animal models of Parkinson's disease by Poliquin, Pierre O, Chen, Jingkui, Cloutier, Mathieu, Trudeau, Louis-Éric, Jolicoeur, Mario

“…Parkinson's disease (PD) is a multifactorial disease known to result from a variety of factors. Although age is the principal risk factor, other etiological…”
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Analysis of Catharanthus roseus alkaloids by HPLC by Hisiger, Steve, Jolicoeur, Mario

“…Catharanthus roseus is a medicinal plant from which secondary metabolites used in chemotherapy to treat diverse cancers are extracted. The well known high…”
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Unraveling the metabolism of HEK-293 cells using lactate isotopomer analysis by Henry, Olivier, Jolicoeur, Mario, Kamen, Amine

“…HEK-293 is the most extensively used human cell line for the production of viral vectors and is gaining increasing attention for the production of recombinant…”
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Hyperosmolarity Triggers the Warburg Effect in Chinese Hamster Ovary Cells and Reveals a Reduced Mitochondria Horsepower by da Veiga Moreira, Jorgelindo, De Staercke, Lenny, César Martínez-Basilio, Pablo, Gauthier-Thibodeau, Sandrine, Montégut, Léa, Schwartz, Laurent, Jolicoeur, Mario

“…Tumor cells are known to favor a glycolytic metabolism over oxidative phosphorylation (OxPhos), which takes place in mitochondria, to produce the energy and…”
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Identifying Biomarkers of Wharton's Jelly Mesenchymal Stromal Cells Using a Dynamic Metabolic Model: The Cell Passage Effect by Laflaquière, Benoît, Leclercq, Gabrielle, Choey, Chandarong, Chen, Jingkui, Peres, Sabine, Ito, Caryn, Jolicoeur, Mario

“…Because of their unique ability to modulate the immune system, mesenchymal stromal cells (MSCs) are widely studied to develop cell therapies for detrimental…”
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Restoration of Physiological Levels of Uric Acid and Ascorbic Acid Reroutes the Metabolism of Stored Red Blood Cells by Bardyn, Manon, Chen, Jingkui, Dussiot, Michaël, Crettaz, David, Schmid, Lucas, Längst, Emmanuel, Amireault, Pascal, Tissot, Jean-Daniel, Jolicoeur, Mario, Prudent, Michel

“…After blood donation, the red blood cells (RBCs) for transfusion are generally isolated by centrifugation and then filtrated and supplemented with additive…”
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Impact of Epidermal Growth Factor Tethering Strategy on Cellular Response by Liberelle, Benoît, Boucher, Cyril, Chen, Jingkui, Jolicoeur, Mario, Durocher, Yves, De Crescenzo, Gregory

“…In an effort to evaluate the impact of various epidermal growth factor (EGF) grafting strategies upon cell surface receptor activation and cell adhesion, we…”
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Human corneal epithelial cell response to epidermal growth factor tethered via coiled-coil interactions by Boucher, Cyril, Ruiz, Juan-Carlos, Thibault, Marc, Buschmann, Michael D, Wertheimer, Michael R, Jolicoeur, Mario, Durocher, Yves, De Crescenzo, Gregory

“…Abstract The development of new strategies for protein immobilization to control cell adhesion, growth and differentiation is of prime interest in the field of…”
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Chitosan rate of uptake in HEK293 cells is influenced by soluble versus microparticle state and enhanced by serum-induced cell metabolism and lactate-based media acidification by Hoemann, Caroline D, Guzmán-Morales, Jessica, Tran-Khanh, Nicolas, Lavallée, Geneviève, Jolicoeur, Mario, Lavertu, Marc

“…Chitosan is a biocompatible polysaccharide composed of glucosamine and N-acetylglucosamine. The polymer has a unique behavior of fluctuating between soluble…”
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