Search Results - "Jokiranta, T.Sakari"

Functional properties of complement factor H-related proteins FHR-3 and FHR-4: binding to the C3d region of C3b and differential regulation by heparin by Hellwage, Jens, Jokiranta, T.Sakari, Koistinen, Vesa, Vaarala, Outi, Meri, Seppo, Zipfel, Peter F.

“…The human factor H-related proteins FHR-3 and FHR-4 are members of a family of proteins related to the complement factor H. Here, we report that the two…”
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HUS and atypical HUS by Jokiranta, T.Sakari

“…Hemolytic uremic syndrome (HUS) is a thrombotic microangiopathy characterized by intravascular hemolysis, thrombocytopenia, and acute kidney failure. HUS is…”
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FHL-1/reconectin and factor H: two human complement regulators which are encoded by the same gene are differently expressed and regulated by Friese, Manuel A, Hellwage, Jens, Jokiranta, T.Sakari, Meri, Seppo, Peter, Hans H, Eibel, Hermann, Zipfel, Peter F

“…FHL-1/reconectin and factor H are two human complement regulators which are encoded by a single gene. FHL-1/reconectin contains the first 7 of 20 SCR protein…”
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Disturbed sialic acid recognition on endothelial cells and platelets in complement attack causes atypical hemolytic uremic syndrome by Hyvärinen, Satu, Meri, Seppo, Jokiranta, T.Sakari

“…Uncontrolled activation of the complement system against endothelial and blood cells is central to the pathogenesis of atypical hemolytic uremic syndrome…”
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Complement resistance mechanisms of streptococci by Jarva, Hanna, Jokiranta, T.Sakari, Würzner, Reinhard, Meri, Seppo

“…Group A streptococcus (GAS, Streptococcus pyogenes), group B streptococcus (GBS, Streptococcus agalactiae) and pneumococcus ( Streptococcus pneumoniae) are all…”
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Multiple ligand binding sites on domain seven of human complement factor H by Giannakis, Eleni, Male, Dean A., Ormsby, Rebecca J., Mold, Carolyn, Jokiranta, T.Sakari, Ranganathan, Shoba, Gordon, David L.

“…Foreign particles and damaged host cells can activate the complement system leading to their destruction by the host defense system. Factor H (fH) plays a…”
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The factor H protein family by Zipfel, Peter F, Jokiranta, T.Sakari, Hellwage, Jens, Koistinen, Vesa, Meri, Seppo

“…The factor H gene family provides a prime example of a multidomain multifunctional protein family whose individual members are defined by conserved common…”
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Complement C3b interactions studied with surface plasmon resonance technique by Jokiranta, T.Sakari, Westin, Jerker, Nilsson, Ulf R., Nilsson, Bo, Hellwage, Jens, Löfås, Stefan, Gordon, David L., Ekdahl, Kristina Nilsson, Meri, Seppo

“…The surface plasmon resonance (SPR) phenomenon is utilized in a number of new real time biosensors. In this study, we have used this technique to study…”
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Complement in disease: closing the millennium by Hellwage, Jens, Jokiranta, T.Sakari, Meri, Seppo

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Extracellular domain of type I receptor for transforming growth factor-β: molecular modelling using protectin (CD59) as a template by Jokiranta, T.Sakari, Tissari, Jorma, Teleman, Olle, Meri, Seppo

“…We have observed that the extracellular domain of TβRI and protectin (CD59), an inhibitor of the membrane attack complex of complement, share structural…”
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