Search Results - "Jokar, Safura"

Functionalized mesoporous silica-coated magnetic graphene oxide by polyglycerol-g-polycaprolactone with pH-responsive behavior: Designed for targeted and controlled doxorubicin delivery by Pourjavadi, Ali, Tehrani, Zahra Mazaheri, Jokar, Safura

“…In the present work a novel multifunctional drug nanocarrier was prepared. Polyglycerol-g-polycaprolactone was grafted on Mesoporous silica-coated magnetic…”
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Targeting Caveolin-1 and Claudin-5 with AY9944, Improve Blood–Brain Barrier Permeability; Computational Simulation and Experimental Study by Gholami, Leila, Jokar, Safura, Fatahi, Yousef, Samandari, Hedayat, Hamzehalipour Almaki, Javad, Hosseini, Marjan, Parviz, Mohsen

“…The current study aimed to determine the protective effect of AY9944 related to Caveolin-1 and Claudin-5 role in lipid raft, which can rescue the blood–brain…”
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The Footprint of Exosomes in the Radiation-Induced Bystander Effects by Jokar, Safura, Marques, Inês A., Khazaei, Saeedeh, Martins-Marques, Tania, Girao, Henrique, Laranjo, Mafalda, Botelho, Maria Filomena

“…Radiation therapy is widely used as the primary treatment option for several cancer types. However, radiation therapy is a nonspecific method and associated…”
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Synthesis, biological evaluation, and in silico study of novel coumarin-quinazoline analogs as potential Anti-Angiogenesis agents by Emamgholipour, Zahra, Dabirian, Sara, Peytam, Fariba, Saeedian Moghadam, Ebrahim, Firoozpour, Loghman, Safavi, Maliheh, Esmaeil Sadat-Ebrahimi, Seyed, Barazandeh Tehrani, Maliheh, Amini, Mohsen, Khalaj, Ali, Jokar, Safura, Bavi, Omid, Reza Bijanzadeh, Hamid, Foroumadi, Alireza

“…[Display omitted] •Novel series of coumarin-quinazoline derivatives were successfully designed and synthesized.•Compound 13f demonstrated notable inhibitory…”
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Preclinical study of a new 177Lu-labeled somatostatin receptor antagonist in HT-29 human colorectal cancer cells by Behnammanesh, Hossein, Erfani, Mostafa, Hajiramezanali, Maliheh, Jokar, Safura, Geramifar, Parham, Sabzevari, Omid, Amini, Mohsen, Mazidi, Seyed Mohammad, Beiki, Davood

“…Objective(s): Somatostatin receptor-positive neuroendocrine tumors have been targeted using various peptide analogs radiolabeled with therapeutic radionuclides…”
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Chitosan based supramolecular polypseudorotaxane as a pH-responsive polymer and their hybridization with mesoporous silica-coated magnetic graphene oxide for triggered anticancer drug delivery by Pourjavadi, Ali, Mazaheri Tehrani, Zahra, Jokar, Safura

“…Chitosan based polyseudorotaxane was designed as a pH-responsive supramolecular polymeric shell around the mesoporous silica-coated magnetic graphene oxide…”
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Design of peptide-based inhibitor agent against amyloid-β aggregation: Molecular docking, synthesis and in vitro evaluation by Jokar, Safura, Erfani, Mostafa, Bavi, Omid, Khazaei, Saeedeh, Sharifzadeh, Mohammad, Hajiramezanali, Malihe, Beiki, Davood, Shamloo, Amir

“…[Display omitted] •The molecular interactions of designed peptides against Aβ peptide were evaluated by the molecular docking.•Targeting peptide synthesis of…”
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Recent Clinical Implications of FAPI: Imaging and Therapy by Kiani, Mahshid, Jokar, Safura, Hassanzadeh, Leila, Behnammanesh, Hossein, Bavi, Omid, Beiki, Davood, Assadi, Majid

“…The fibroblast activation protein (FAP) is a biomarker that is selectively overexpressed on cancer-associated fibroblasts (CAFs) in various types of tumoral…”
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RadioLabeling of the Mutant form of Anti-PlGF Nanobody by 99mTc-Tricarbonyl by Rezazadeh, Tahereh, Tabatabaee Bafroee, Akram Sadat, Shahhosseini, Soraya, Jokar, Safura, Hasanramezani, Abolfazl, Arezumand, Roghaye

“…Background: Molecular imaging is a highly effective method for diagnosing cancer and evaluating treatment. A molecular tracer often consists of two segments: A…”
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Recent advances in the design and applications of amyloid-β peptide aggregation inhibitors for Alzheimer’s disease therapy by Jokar, Safura, Khazaei, Saeedeh, Behnammanesh, Hossein, Shamloo, Amir, Erfani, Mostafa, Beiki, Davood, Bavi, Omid

“…Alzheimer’s disease (AD) is an irreversible neurological disorder that progresses gradually and can cause severe cognitive and behavioral impairments. This…”
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Synthesis, biological evaluation and preclinical study of a novel 99mTc-peptide: A targeting probe of amyloid-β plaques as a possible diagnostic agent for Alzheimer’s disease by Jokar, Safura, Behnammanesh, Hossein, Erfani, Mostafa, Sharifzadeh, Mohammad, Gholami, Mahdi, Sabzevari, Omid, Amini, Mohsen, Geramifar, Parham, Hajiramezanali, Maliheh, Beiki, Davood

“…[Display omitted] •Peptide targeting Aβ plaques was successfully synthesized.•Peptide radiolabeling was done by cyclopentadienyl tricarbonyl 99mTc…”
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Self-assembled peptide/polymer hybrid nanoplatform for cancer immunostimulating therapies by Khazaei, Saeedeh, Varela-Calviño, Ruben, Rad-Malekshahi, Mazda, Quattrini, Federico, Jokar, Safura, Rezaei, Nima, Balalaie, Saeed, Haririan, Ismaeil, Csaba, Noemi, Garcia-Fuentes, Marcos

“…Integrating peptide epitopes in self-assembling materials is a successful strategy to obtain nanovaccines with high antigen density and improved efficacy. In…”
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Design, preparation and biological evaluation of a 177Lu-labeled somatostatin receptor antagonist for targeted therapy of neuroendocrine tumors by Behnammanesh, Hossein, Jokar, Safura, Erfani, Mostafa, Geramifar, Parham, Sabzevari, Omid, Amini, Mohsen, Mazidi, Seyed Mohammad, Hajiramezanali, Maliheh, Beiki, Davood

“…[Display omitted] •Peptide sequences were designed by molecular docking study.•Using the 3-Benzothienylalanyl in antagonist improves the receptor binding…”
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Synthesis, biological evaluation and preclinical study of a novel 99m Tc-peptide: A targeting probe of amyloid-β plaques as a possible diagnostic agent for Alzheimer's disease by Jokar, Safura, Behnammanesh, Hossein, Erfani, Mostafa, Sharifzadeh, Mohammad, Gholami, Mahdi, Sabzevari, Omid, Amini, Mohsen, Geramifar, Parham, Hajiramezanali, Maliheh, Beiki, Davood

“…With respect to the main role of amyloid-β (Aβ) plaques as one of the pathological hallmarks in the brain of Alzheimer's patients, the development of new…”
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Design, preparation and biological evaluation of a 177 Lu-labeled somatostatin receptor antagonist for targeted therapy of neuroendocrine tumors by Behnammanesh, Hossein, Jokar, Safura, Erfani, Mostafa, Geramifar, Parham, Sabzevari, Omid, Amini, Mohsen, Mazidi, Seyed Mohammad, Hajiramezanali, Maliheh, Beiki, Davood

“…Somatostatin receptor-targeted radionuclide therapy has become an effective treatment in patients with neuroendocrine tumors. Recently, investigations on the…”
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Design of a New 99m Tc-radiolabeled Cyclo-peptide as Promising Molecular Imaging Agent of CXCR 4 Receptor: Molecular Docking, Synthesis, Radiolabeling, and Biological Evaluation by Hassanzadeh, Leila, Erfani, Mostafa, Jokar, Safura, Shariatpanahi, Marjan

“…C-X-C Chemokine receptor type 4 (CXCR4) is often overexpressed or overactivated in different types and stages of cancer disease. Therefore, it is considered a…”
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