Search Results - "Joiner, Michael C."

Proton versus photon radiation therapy: A clinical review by Chen, Zhe, Dominello, Michael M, Joiner, Michael C, Burmeister, Jay W

“…While proton radiation therapy offers substantially better dose distribution characteristics than photon radiation therapy in certain clinical applications,…”
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Low-Dose Irradiation Promotes Persistent Oxidative Stress and Decreases Self-Renewal in Hematopoietic Stem Cells by Rodrigues-Moreira, Sarah, Moreno, Stéphanie G., Ghinatti, Giulia, Lewandowski, Daniel, Hoffschir, Françoise, Ferri, Federica, Gallouet, Anne-Sophie, Gay, Denise, Motohashi, Hozumi, Yamamoto, Masayuki, Joiner, Michael C., Gault, Nathalie, Romeo, Paul-Henri

“…Despite numerous observations linking protracted exposure to low-dose (LD) radiation and leukemia occurrence, the effects of LD irradiation on hematopoietic…”
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Bioeffect modeling and equieffective dose concepts in radiation oncology – Terminology, quantities and units by Bentzen, Søren M, Dörr, Wolfgang, Gahbauer, Reinhard, Howell, Roger W, Joiner, Michael C, Jones, Bleddyn, Jones, Dan T.L, van der Kogel, Albert J, Wambersie, André, Whitmore, Gordon

“…Abstract The International Commission on Radiation Units and Measurements (ICRU) Report Committee on “Bioeffect Modeling and Biologically Equivalent Dose…”
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The Effects of G2-Phase Enrichment and Checkpoint Abrogation on Low-Dose Hyper-Radiosensitivity by Krueger, Sarah A., Ph.D, Wilson, George D., Ph.D, Piasentin, Evano, B.S, Joiner, Michael C., Ph.D, Marples, Brian, Ph.D

“…Purpose An association between low-dose hyper-radiosensitivity (HRS) and the ”early” G2/M checkpoint has been established. An improved molecular understanding…”
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Neutron exposures in human cells: bystander effect and relative biological effectiveness by Seth, Isheeta, Schwartz, Jeffrey L, Stewart, Robert D, Emery, Robert, Joiner, Michael C, Tucker, James D

“…Bystander effects have been observed repeatedly in mammalian cells following photon and alpha particle irradiation. However, few studies have been performed to…”
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Cytogenetic Low-Dose Hyperradiosensitivity Is Observed in Human Peripheral Blood Lymphocytes by Seth, Isheeta, PhD, Joiner, Michael C., PhD, Tucker, James D., PhD

“…Purpose The shape of the ionizing radiation response curve at very low doses has been the subject of considerable debate. Linear-no-threshold (LNT) models are…”
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Accurate Gene Expression-Based Biodosimetry Using a Minimal Set of Human Gene Transcripts by Tucker, James D., PhD, Joiner, Michael C., PhD, Thomas, Robert A., PhD, Grever, William E., PhD, Bakhmutsky, Marina V., PhD, Chinkhota, Chantelle N., PhD, Smolinski, Joseph M., PhD, Divine, George W., PhD, Auner, Gregory W., PhD

“…Purpose Rapid and reliable methods for conducting biological dosimetry are a necessity in the event of a large-scale nuclear event. Conventional biodosimetry…”
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Estimating the Lowest Detectable Dose of Ionizing Radiation by the Cytokinesis-Block Micronucleus Assay by Tucker, James D., Vadapalli, Malati, Joiner, Michael C., Ceppi, Marcello, Fenech, Michael, Bonassi, Stefano

“…The frequency of binucleated cells containing one or more micronuclei (MNBN cells) in cytokinesis-blocked peripheral blood lymphocytes can be used to determine…”
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Gene expression-based dosimetry by dose and time in mice following acute radiation exposure by Tucker, James D, Divine, George W, Grever, William E, Thomas, Robert A, Joiner, Michael C, Smolinski, Joseph M, Auner, Gregory W

“…Rapid and reliable methods for performing biological dosimetry are of paramount importance in the event of a large-scale nuclear event. Traditional dosimetry…”
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Transition in Survival From Low-Dose Hyper-Radiosensitivity to Increased Radioresistance Is Independent of Activation of ATM SER1981 Activity by Krueger, Sarah A., Ph.D, Collis, Spencer J., Ph.D, Joiner, Michael C., Ph.D, Wilson, George D., Ph.D, Marples, Brian, Ph.D

“…Purpose The molecular basis of low-dose hyper-radiosensitivity (HRS) is only partially understood. The aim of this study was to define the roles of ataxia…”
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Radiation-Induced Esophagitis is Mitigated by Soy Isoflavones by Fountain, Matthew D, Abernathy, Lisa M, Lonardo, Fulvio, Rothstein, Shoshana E, Dominello, Michael M, Yunker, Christopher K, Chen, Wei, Gadgeel, Shirish, Joiner, Michael C, Hillman, Gilda G

“…Lung cancer patients receiving radiotherapy present with acute esophagitis and chronic fibrosis, as a result of radiation injury to esophageal tissues. We have…”
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Developing point of care and high-throughput biological assays for determining absorbed radiation dose by Joiner, Michael C, Thomas, Robert A, Grever, William E, Smolinski, Joseph M, Divine, George W, Konski, Andre A, Auner, Gregory W, Tucker, James D

“…Abstract Background and purpose Systems are being developed to assess radiation exposure based on leukocyte mRNA levels obtained by finger-stick sampling. The…”
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Genistein potentiates inhibition of tumor growth by radiation in a prostate cancer orthotopic model by Hillman, Gilda G, Wang, Yu, Kucuk, Omer, Che, Mingxin, Doerge, Daniel R, Yudelev, Mark, Joiner, Michael C, Marples, Brian, Forman, Jeffrey D, Sarkar, Fazlul H

“…Objective: We have shown previously that pretreatment with genistein potentiated cell killing induced by radiation in human PC-3 prostate carcinoma cell line…”
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Axitinib Improves Radiotherapy in Murine Xenograft Lung Tumors by Hillman, Gilda G, Lonardo, Fulvio, Hoogstra, David J, Rakowski, Joseph, Yunker, Christopher K, Joiner, Michael C, Dyson, Gregory, Gadgeel, Shirish, Singh-Gupta, Vinita

“…Abstract A third of patients with non-small cell lung cancer (NSCLC) present with un-resectable stage III locally advanced disease and are currently treated by…”
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How to overcome (and exploit) tumor hypoxia for targeted gene therapy by Greco, Olga, Marples, Brian, Joiner, Michael C., Scott, Simon D.

“…Tumor hypoxia has long been recognized as a critical issue in oncology. Resistance of hypoxic areas has been shown to affect treatment outcome after radiation,…”
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International Conference on Advances in Radiation Oncology (ICARO): outcomes of an IAEA meeting by Salminen, Eeva K, Kiel, Krystyna, Ibbott, Geoffrey S, Joiner, Michael C, Rosenblatt, Eduardo, Zubizarreta, Eduardo, Wondergem, Jan, Meghzifene, Ahmed

“…The IAEA held the International Conference on Advances in Radiation Oncology (ICARO) in Vienna on 27-29 April 2009. The Conference dealt with the issues and…”
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AAPM Task Group Report 267: A joint AAPM GEC‐ESTRO report on biophysical models and tools for the planning and evaluation of brachytherapy by Chen, Zhe (Jay), Li, X. Allen, Brenner, David J., Hellebust, Taran P., Hoskin, Peter, Joiner, Michael C., Kirisits, Christian, Nath, Ravinder, Rivard, Mark J., Thomadsen, Bruce R., Zaider, Marco

“…Brachytherapy utilizes a multitude of radioactive sources and treatment techniques that often exhibit widely different spatial and temporal dose delivery…”
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Acrokeratosis Paraneoplastica Associated with Cervical Squamous Cell Carcinoma by Bishop, Michael, Hurst, Newton, Joiner, Michael C., Daveluy, Steven D., Squires, Bryan, Miller, Steven R.

“…Background. Acrokeratosis paraneoplastica, or Bazex syndrome, is a paraneoplastic syndrome characterized by cutaneous psoriasiform lesions with associated…”
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Three discipline collaborative radiation therapy (3DCRT) special debate: Systemic radiotherapy using targeted isotopes is the best hope for advancing curative radiation therapy by Koontz, Bridget F., Koritzinsky, Marianne, Zoberi, Jacqueline E., Brown, Stephen L., Ding, Xuanfeng, Wong, Jeffrey, Joiner, Michael C., Dominello, Michael M., Burmeister, Jay

“…[...]discussion of controversies or changes in practice within radiation oncology involves input from all three disciplines. [...]the recent development and…”
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Characterization of the Response of 9L and U-251N Orthotopic Brain Tumors to 3D Conformal Radiation Therapy by Valadie, O. Grahm, Brown, Stephen L., Farmer, Katelynn, Nagaraja, Tavarekere N., Cabral, Glauber, Shadaia, Sheldon, Divine, George W., Knight, Robert A., Lee, Ian Y., Dolan, Jennifer, Rusu, Sam, Joiner, Michael C., Ewing, James R.

“…In a study employing MRI-guided stereotactic radiotherapy (SRS) in two orthotopic rodent brain tumor models, the radiation dose yielding 50% survival (the…”
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