Search Results - "Joiner, C H"

Cation transport and volume regulation in sickle red blood cells by Joiner, C H

“…Cellular dehydration is one of several pathological features of the sickle cell. Cation depletion is quite severe in certain populations of sickle cells and…”
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Regulation of K-Cl cotransport by Syk and Src protein tyrosine kinases in deoxygenated sickle cells by Merciris, P, Claussen, W J, Joiner, C H, Giraud, F

“…Protein tyrosine kinases (PTK) of the Src family are thought to suppress K-Cl cotransport (KCC) activity via negative regulation of protein phosphatases…”
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Deoxygenation of sickle red blood cells stimulates KCl cotransport without affecting Na+/H+ exchange by Joiner, C H, Jiang, M, Fathallah, H, Giraud, F, Franco, R S

“…KCl cotransport activated by swelling of sickle red blood cells (SS RBC)is inhibited by deoxygenation. Yet recent studies found a Cl--dependent increase in…”
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Dehydration of mature and immature sickle red blood cells during fast oxygenation/deoxygenation cycles: role of KCl cotransport and extracellular calcium by McGoron, Anthony J., Joiner, Clinton H., Palascak, Mary B., Claussen, William J., Franco, Robert S.

“…Sickle red blood cells (RBC) become dehydrated as a consequence of potassium loss. This process depends at least partly on deoxygenation and may be influenced…”
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Universal newborn screening for hemoglobinopathies by Joiner, Clinton H.

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Dehydration of transferrin receptor-positive sickle reticulocytes during continuous or cyclic deoxygenation : Role of KCl cotransport and extracellular calcium by FRANCO, R. S, PALASCAK, M, THOMPSON, H, RUCKNAGEL, D. L, JOINER, C. H

“…The K+ efflux that mediates sickle-cell dehydration may occur through several pathways, including two with a high capacity for mediating rapid K+ loss, KCl…”
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Deoxygenation-induced cation fluxes in sickle cells. IV. Modulation by external calcium by Joiner, C H, Jiang, M, Franco, R S

“…Net cation movements were measured in low-density sickle red blood cells (SS RBC) in the presence and absence of oxygen. External Ca2+ (Ca2+o) partially…”
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Deoxygenation-induced cation fluxes in sickle cells. III. Cation selectivity and response to pH and membrane potential by Joiner, C H, Morris, C L, Cooper, E S

“…Deoxygenation of sickle cells increases membrane permeability to Na, K, and Ca and contributes to cellular cation depletion. This study examines the…”
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Deoxygenation-induced alterations in sickle cell membrane cholesterol exchange by Kavecansky, J, Schroeder, F, Joiner, C H

“…Changes in a membrane sterol exchange of sickle red blood cells (SS RBC) induced by deoxygenation were studied using the fluorescent cholesterol analogue…”
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A randomized, controlled trial of very early prophylactic ligation of the ductus arteriosus in babies who weighed 1000 g or less at birth by Cassady, G, Crouse, D T, Kirklin, J W, Strange, M J, Joiner, C H, Godoy, G, Odrezin, G T, Cutter, G R, Kirklin, J K, Pacifico, A D

“…We speculated that prophylactic ligation of the ductus arteriosus would reduce mortality and morbidity in very-low-birth-weight infants. To test this…”
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The formation of transferrin receptor-positive sickle reticulocytes with intermediate density is not determined by fetal hemoglobin content by FRANCO, R. S, THOMPSON, H, PALASCAK, M, JOINER, C. H

“…Erythrocyte dehydration is an important feature of sickle cell disease, leading to increased sickle hemoglobin polymerization and decreased red blood cell…”
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In situ localization of sodium-potassium ATPase mRNA in developing mouse lung epithelium by Crump, R G, Askew, G R, Wert, S E, Lingrel, J B, Joiner, C H

“…The ontogeny of Na(+)-K(+)-adenosinetriphosphatase (ATPase) mRNA in the mouse lung was examined, using alpha- and beta-isoform-specific probes in Northern blot…”
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Deoxygenation-Induced Cation Fluxes in Sickle Cells: II. Inhibition by Stilbene Disulfonates by Joiner, Clinton H.

“…Deoxygenation-induced cation movements in sickle cells were inhibited 80% to 85% by the anion transport inhibitor, 4.4'-diisothiocyano-2,2'disulfostilbene…”
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Erythrocyte membrane lateral sterol domains: A dehydroergosterol fluorescence polarization study by Kavecansky, Juraj, Joiner, Clinton H, Schroeder, Friedhelm

“…Structural domains of cholesterol and their regulation in the erythrocyte membrane are poorly understood. Dehydroergosterol fluorescence polarization change…”
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Should children with hemoglobinopathies be offered unrelated-donor cord blood stem cell transplantation? by Harris, Richard E., Joiner, Clinton H.

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Increased Cation Permeability in Mutant Mouse Red Blood Cells With Defective Membrane Skeletons by Joiner, Clinton H., Franco, Robert S., Jiang, Maorong, Franco, Mark S., Barker, Jane E., Lux, Samuel E.

“…Cellular cation homeostasis in mouse erythrocytes with defective membrane skeletons was examined in three mouse mutants, hemolytic anemia (sphha/sphha),…”
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Fetal hemoglobin and potassium in isolated transferrin receptor-positive dense sickle reticulocytes by Franco, R S, Barker-Gear, R, Miller, M A, Williams, S M, Joiner, C H, Rucknagel, D L

“…A subset of sickle cells have an increased density at the reticulocyte stage of development, indicating that they are either abnormally dense upon release from…”
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Cation depletion by the sodium pump in red cells with pathologic cation leaks: sickle cells and xerocytes by JOINER, C. H, PLATT, O. S, LUX, S. E. IV

“…The mechanism by which sickle cells and xerocytic red cells become depleted of cations in vivo has not been identified previously. Both types of cells exhibit…”
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Deoxygenation-induced changes in sickle cell-sickle cell adhesion by MORRIS, C. L, RUCKNAGEL, D. L, JOINER, C. H

“…The tendency for sickle cells to adhere to each other is increased in oxygenated sickle blood in parallel with cell density. The increased adherence of these…”
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The correlation between ouabain binding and potassium pump inhibition in human and sheep erythrocytes by Joiner, C H, Lauf, P K

“…1. [3H]Ouabain binding to human and sheep red blood cells was shown to be specific for receptors associated with Na/K transport. Virtually all tritium binding…”
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