Search Results - "Johnstone, David E."
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Canadian Cardiovascular Society Quality Indicators for Heart Failure
Published in Canadian journal of cardiology (01-08-2016)“…Abstract A working group was convened by the Canadian Cardiovascular Society (CCS) in 2010 to identify quality indicators (QIs) for heart failure (HF). Using…”
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Pan-Canadian Cardiovascular Data Definitions and Quality Indicators: A Status Update
Published in Canadian journal of cardiology (01-09-2012)“…Abstract After the 2009 publication of Building a Heart Healthy Canada , the Canadian Cardiovascular Society was commissioned to address a long-standing…”
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Obesity-induced lysine acetylation increases cardiac fatty acid oxidation and impairs insulin signalling
Published in Cardiovascular research (01-09-2014)“…Lysine acetylation is a novel post-translational pathway that regulates the activities of enzymes involved in both fatty acid and glucose metabolism. We…”
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Heart failure clinics are associated with clinical benefit in both tertiary and community care settings: Data from the Improving Cardiovascular Outcomes in Nova Scotia (ICONS) registry
Published in Canadian journal of cardiology (01-09-2009)“…Background Heart failure (HF) clinics are known to improve outcomes of patients with HF. Studies have been limited to single, usually tertiary centres whose…”
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Weight loss enhances cardiac energy metabolism and function in heart failure associated with obesity
Published in Diabetes, obesity & metabolism (01-08-2019)“…Aims Obesity is associated with high rates of cardiac fatty acid oxidation, low rates of glucose oxidation, cardiac hypertrophy and heart failure. Whether…”
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Something Old Holds Potential to Be Something New in Heart Failure: Allopurinol Revisited
Published in Canadian journal of cardiology (01-11-2012)Get full text
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Lowering body weight in obese mice with diastolic heart failure improves cardiac insulin sensitivity and function: implications for the obesity paradox
Published in Diabetes (New York, N.Y.) (01-05-2015)“…Recent studies suggest improved outcomes and survival in obese heart failure patients (i.e., the obesity paradox), although obesity and heart failure…”
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The Effect of Spironolactone Use on Heart Failure Mortality: A Population-Based Study
Published in Journal of cardiac failure (01-04-2007)“…Abstract Background Spironolactone use for heart failure (HF) has increased dramatically after the publication of the Randomized Aldactone Evaluation Study…”
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Relationship of the Glu298Asp polymorphism of the endothelial nitric oxide synthase gene and early-onset coronary artery disease
Published in The American heart journal (01-10-2001)“…Background The Glu298Asp polymorphism of endothelial nitric oxide synthase (eNOS) gene has been associated with coronary artery disease (CAD) in some but not…”
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Canadian Cardiovascular Society consensus conference recommendations on heart failure 2006: Diagnosis and management
Published in Canadian journal of cardiology (2006)“…Heart failure remains a common diagnosis, especially in older individuals. It continues to be associated with significant morbidity and mortality, but major…”
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Use of complementary and alternative medical therapies in patients with cardiovascular disease
Published in The American heart journal (01-05-2003)“…Complementary and alternative medical (CAM) therapies are becoming increasingly popular, yet little information is available about the prevalence and patterns…”
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Prognostic significance of plasma norepinephrine in patients with asymptomatic left ventricular dysfunction
Published in Circulation (New York, N.Y.) (15-08-1996)“…Background Elevated plasma neurohormonal levels are associated with increased mortality rates in patients with symptomatic heart failure. A previous Studies of…”
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Relation of genetic polymorphisms of apolipoprotein E, angiotensin converting enzyme, apolipoprotein B-100, and glycoprotein IIIa and early-onset coronary heart disease
Published in Clinical biochemistry (01-06-1999)“…Objective: Apolipoprotein E (APOE) E4, apolipoprotein B-100 ( APOB) Q3611 allele, the angiotensin converting enzyme ( ACE) deletion (D) allele and glycoprotein…”
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Relation of a Common Mutation in Methylenetetrahydrofolate Reductase to Plasma Homocysteine and Early Onset Coronary Artery Disease
Published in Clinical biochemistry (01-03-1998)“…Objective: In the presence of low serum folate, mutant 5,10-methylenetetrahydrofolate reductase (MTHFR+ [A223V/C677T]) in the homozygous state (+/+), may…”
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Undocumented patient information: an impediment to quality of care
Published in The American journal of medicine (15-02-2003)“…Poor documentation in medical records might reduce the quality of care and undermine analyses based on retrospective chart reviews. We assessed the…”
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Natural history and patterns of current practice in heart failure
Published in Journal of the American College of Cardiology (01-10-1993)“…A total of 6,273 consecutive relatively unselected patients with heart failure or left ventricular dysfunction, or both (mean age 62 ± 12 years, mean ejection…”
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Waiting for cardiac surgery: results of a risk-stratified queuing process
Published in Circulation (New York, N.Y.) (18-09-2001)“…The Queen Elizabeth II Health Sciences Centre uses a weekly peer-review conference of cardiovascular experts to prioritize each surgical case to 1 of 4 queues…”
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Relation of neurohumoral activation to clinical variables and degree of ventricular dysfunction: A report from the registry of studies of left ventricular dysfunction
Published in Journal of the American College of Cardiology (01-05-1994)“…Objectives. This study examined the relation between neurohumoral activation and severity of left ventricular dysfunction and congestive heart failure in a…”
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Effect of long-term enalapril therapy on neurohormones in patients with left ventricular dysfunction
Published in The American journal of cardiology (01-06-1995)“…The aim of this study was to compare the long-term effects of treatment with enalapril or placebo on plasma neurohormones in patients with left ventricular…”
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Trends in event rate and case fatality of patients hospitalized with myocardial infarction between 1984 and 2001
Published in Canadian journal of physiology and pharmacology (01-01-2006)“…Between 1984 and 1993, prevalence and case fatality of hospitalized acute myocardial infarction (AMI) had declined in the population of Halifax County. We…”
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