Search Results - "Johnston, Margaret I"
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HIV Vaccine Research: The Way Forward
Published in Science (American Association for the Advancement of Science) (25-07-2008)“…The need to broaden research directed at answering fundamental questions in HIV vaccine discovery through laboratory, nonhuman primate (NHP), and clinical…”
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An HIV Vaccine — Evolving Concepts
Published in The New England journal of medicine (17-05-2007)“…The unique features of the human immunodeficiency virus (HIV) envelope protein have thwarted efforts to identify a protective vaccine. However, a vaccine that…”
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The complex challenges of HIV vaccine development require renewed and expanded global commitment
Published in The Lancet (British edition) (01-02-2020)Get full text
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An HIV Vaccine — Challenges and Prospects
Published in The New England journal of medicine (28-08-2008)“…An HIV vaccine has thus far been elusive. Drs. Margaret Johnston and Anthony Fauci remain cautiously optimistic that a substantial increase in our…”
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HIV Vaccine Development — Improving on Natural Immunity
Published in The New England journal of medicine (08-09-2011)“…Since our natural immune response to HIV infection is ineffective, a key goal for an HIV vaccine is to induce a response different from that induced by natural…”
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HIV vaccines: progress and promise
Published in Journal of the International AIDS Society (01-11-2021)“…The scientific community, especially HIV vaccine trialists with established clinical sites, community relationships and laboratory procedures, quickly pivoted…”
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Present Status and Future Prospects for HIV Therapies
Published in Science (American Association for the Advancement of Science) (28-05-1993)“…Since the discovery of human immunodeficiency virus (HIV) in 1983, significant progress has been made toward the discovery, development, and licensing of…”
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The 2010 scientific strategic plan of the Global HIV Vaccine Enterprise
Published in Nature medicine (01-09-2010)“…HIV/AIDS remains one of humanity's greatest challenges. Since 1981, it has claimed over 25 million lives and is currently responsible for over 2.5 million new…”
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The immune space: a concept and template for rationalizing vaccine development
Published in AIDS research and human retroviruses (01-11-2014)“…Empirical testing of candidate vaccines has led to the successful development of a number of lifesaving vaccines. The advent of new tools to manipulate…”
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The Need for a Global HIV Vaccine Enterprise
Published in Science (American Association for the Advancement of Science) (27-06-2003)“…A new collaborative model of research is needed to increase resources, to prioritize the R agenda of the major public- and private-sector stakeholders, and…”
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HIV Vaccine Trial Justified
Published in Science (American Association for the Advancement of Science) (13-02-2004)“…McNeil et al fully agree in Burton et al's recent Policy Forum, which states that phase III trials alone are required to establish the efficacy of HIV…”
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Policy rebuttal. HIV vaccine trial justified
Published in Science (American Association for the Advancement of Science) (13-02-2004)Get full text
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Progress in HIV vaccine development
Published in Current Opinion in Pharmacology (01-10-2001)“…Recent advances in HIV vaccine development include initiation of the first efficacy trials and substantial expansion of the preclinical pipeline. Several…”
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A new era in HIV vaccine development
Published in Expert review of anti-infective therapy (01-04-2007)“…Since the identification of HIV in 1984, the search for a safe and effective vaccine has been relentless. While investigator-initiated research has provided…”
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Outstanding Questions on HIV Vaccine Trial
Published in Science (American Association for the Advancement of Science) (09-07-2004)Get full text
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Current advances in HIV vaccines
Published in Current HIV/AIDS reports (01-04-2004)“…Development of a safe and preventive HIV-1 vaccine is a high priority. Recent advances in HIV vaccine development include an improved understanding of HIV…”
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Progress in the development of an HIV vaccine
Published in Expert opinion on emerging drugs (01-05-2003)“…Despite the remarkable advances that have been made in the last 20 years regarding the molecular virology, pathogenesis and epidemiology of HIV, the…”
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Antibody-nucleic acid interactions. Monoclonal antibodies define different antigenic domains in 2',5'-oligoadenylates
Published in Biochemistry (Easton) (01-08-1985)“…To define the epitopes involved in binding anti-oligonucleotide antibodies, several hybridomas producing monoclonal antibodies directed against…”
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HIV Vaccines: Biological and Clinical Considerations
Published in Current infectious disease reports (01-08-2002)“…The discovery of an HIV-1 vaccine is a high priority. Recent advances in HIV vaccine development include an improved understanding about virus biology and…”
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HIV vaccines: problems and prospects
Published in Hospital practice (1995) (15-05-1997)“…Several lines of evidence now argue strongly that a successful HIV vaccine does not need to block infection completely. It has to mimic what already occurs in…”
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