Search Results - "Johnston, Luke"

Improving adherence and clinical outcomes in self-guided internet treatment for anxiety and depression: randomised controlled trial by Titov, Nickolai, Dear, Blake F, Johnston, Luke, Lorian, Carolyn, Zou, Judy, Wootton, Bethany, Spence, Jay, McEvoy, Peter M, Rapee, Ronald M

“…Depression and anxiety are common, disabling and chronic. Self-guided internet-delivered treatments are popular, but few people complete them. New strategies…”
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Developing a 3D intestinal epithelium model for livestock species by Derricott, Hayley, Luu, Lisa, Fong, Wai Yee, Hartley, Catherine S., Johnston, Luke J., Armstrong, Stuart D., Randle, Nadine, Duckworth, Carrie A., Campbell, Barry J., Wastling, Jonathan M., Coombes, Janine L.

“…The in vitro 3D culture of intestinal epithelium is a valuable resource in the study of its function. Organoid culture exploits stem cells’ ability to…”
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The developmental basis of fingerprint pattern formation and variation by Glover, James D., Sudderick, Zoe R., Shih, Barbara Bo-Ju, Batho-Samblas, Cameron, Charlton, Laura, Krause, Andrew L., Anderson, Calum, Riddell, Jon, Balic, Adam, Li, Jinxi, Klika, Václav, Woolley, Thomas E., Gaffney, Eamonn A., Corsinotti, Andrea, Anderson, Richard A., Johnston, Luke J., Brown, Sara J., Wang, Sijia, Chen, Yuhang, Crichton, Michael L., Headon, Denis J.

“…Fingerprints are complex and individually unique patterns in the skin. Established prenatally, the molecular and cellular mechanisms that guide fingerprint…”
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The Association between the Substitution of Red Meat with Legumes and the Risk of Primary Liver Cancer in the UK Biobank: A Cohort Study by Bock, Niels, Langmann, Fie, Johnston, Luke W, Ibsen, Daniel B, Dahm, Christina C

“…Primary liver cancer is globally on the rise, partially due to poor diets and sedentary lifestyles. Shifting to more plant-based diets may lower the risk. We…”
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GapClust is a light-weight approach distinguishing rare cells from voluminous single cell expression profiles by Fa, Botao, Wei, Ting, Zhou, Yuan, Johnston, Luke, Yuan, Xin, Ma, Yanran, Zhang, Yue, Yu, Zhangsheng

“…Single cell RNA sequencing (scRNA-seq) is a powerful tool in detailing the cellular landscape within complex tissues. Large-scale single cell transcriptomics…”
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Association of NEFA composition with insulin sensitivity and beta cell function in the Prospective Metabolism and Islet Cell Evaluation (PROMISE) cohort by Johnston, Luke W., Harris, Stewart B., Retnakaran, Ravi, Giacca, Adria, Liu, Zhen, Bazinet, Richard P., Hanley, Anthony J.

“…Aims/hypothesis Our aim was to determine the longitudinal associations of individual NEFA with the pathogenesis of diabetes, specifically with differences in…”
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Transdiagnostic Internet treatment for anxiety disorders: A randomized controlled trial by Titov, Nickolai, Andrews, Gavin, Johnston, Luke, Robinson, Emma, Spence, Jay

“…Clinician-guided Internet-based cognitive behavioural therapy (iCBT) programs are clinically effective at treating specific anxiety disorders. The present…”
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A RCT of a transdiagnostic internet-delivered treatment for three anxiety disorders: examination of support roles and disorder-specific outcomes by Johnston, Luke, Titov, Nickolai, Andrews, Gavin, Spence, Jay, Dear, Blake F

“…Anxiety disorders share common vulnerabilities and symptoms. Disorder-specific treatment is efficacious, but few access evidence-based care. Administering…”
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Predicting long-term progression of Alzheimer's disease using a multimodal deep learning model incorporating interaction effects by Wang, Yifan, Gao, Ruitian, Wei, Ting, Johnston, Luke, Yuan, Xin, Zhang, Yue, Yu, Zhangsheng

“…Identifying individuals with mild cognitive impairment (MCI) at risk of progressing to Alzheimer's disease (AD) provides a unique opportunity for early…”
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Metabolomic profiling of the Dietary Approaches to Stop Hypertension diet provides novel insights for the nutritional epidemiology of type 2 diabetes mellitus by Yashpal, Shahen, Liese, Angela D., Boucher, Beatrice A., Wagenknecht, Lynne E., Haffner, Steven M., Johnston, Luke W., Bazinet, Richard P., Rewers, Marian, Rotter, Jerome I., Watkins, Steve M., Hanley, Anthony J.

“…Adherence to the Dietary Approaches to Stop Hypertension (DASH) diet is inversely associated with type 2 diabetes mellitus (T2DM) risk. Metabolic changes due…”
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Survival prediction of stomach cancer using expression data and deep learning models with histopathological images by Wei, Ting, Yuan, Xin, Gao, Ruitian, Johnston, Luke, Zhou, Jie, Wang, Yifan, Kong, Weiming, Xie, Yujing, Zhang, Yue, Xu, Dakang, Yu, Zhangsheng

“…Accurately predicting patient survival is essential for cancer treatment decision. However, the prognostic prediction model based on histopathological images…”
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The Macrophage Activation Marker Soluble CD163 is Longitudinally Associated With Insulin Sensitivity and β-cell Function by Semnani-Azad, Zhila, Connelly, Philip W, Johnston, Luke W, Retnakaran, Ravi, Harris, Stewart B, Zinman, Bernard, Hanley, Anthony J

“…Abstract Context Chronic inflammation arising from adipose tissue macrophage (ATM) activation may be central in type 2 diabetes etiology. Our objective was to…”
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Stem cell‐derived enteroid cultures as a tool for dissecting host‐parasite interactions in the small intestinal epithelium by Hares, Miriam F., Tiffney, Ellen‐Alana, Johnston, Luke J., Luu, Lisa, Stewart, Christopher J., Flynn, Robin J., Coombes, Janine L.

“…Toxoplasma gondii and Cryptosporidium spp. can cause devastating pathological effects in humans and livestock, and in particular to young or immunocompromised…”
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Clusters of fatty acids in the serum triacylglyceride fraction associate with the disorders of type 2 diabetes by Johnston, Luke W., Liu, Zhen, Retnakaran, Ravi, Zinman, Bernard, Giacca, Adria, Harris, Stewart B., Bazinet, Richard P., Hanley, Anthony J.

“…Our aim was to examine longitudinal associations of triacylglyceride fatty acid (TGFA) composition with insulin sensitivity (IS) and β-cell function. Adults at…”
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Improving adherence and clinical outcomes in self-guided internet treatment for anxiety and depression: a 12-month follow-up of a randomised controlled trial by Titov, Nickolai, Dear, Blake F, Johnston, Luke, McEvoy, Peter M, Wootton, Bethany, Terides, Matthew D, Gandy, Milena, Fogliati, Vincent, Kayrouz, Rony, Rapee, Ronald M

“…A recent paper reported the outcomes of a study examining a new self-guided internet-delivered treatment, the Wellbeing Course, for symptoms of anxiety or…”
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An Efficient and Easy-to-Use Network-Based Integrative Method of Multi-Omics Data for Cancer Genes Discovery by Wei, Ting, Fa, Botao, Luo, Chengwen, Johnston, Luke, Zhang, Yue, Yu, Zhangsheng

“…Identifying personalized driver genes is essential for discovering critical biomarkers and developing effective personalized therapies of cancers. However, few…”
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Effect of familial diabetes status and age at diagnosis on type 2 diabetes risk: a nation-wide register-based study from Denmark by Silverman-Retana, Omar, Hulman, Adam, Nielsen, Jannie, Ekstrøm, Claus T., Carstensen, Bendix, Simmons, Rebecca K., Bjerg, Lasse, Johnston, Luke W., Witte, Daniel R.

“…Aims/hypothesis We assessed whether the risk of developing type 2 diabetes and the age of onset varied with the age at diabetes diagnosis of affected family…”
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An Open-Format Enteroid Culture System for Interrogation of Interactions Between Toxoplasma gondii and the Intestinal Epithelium by Luu, Lisa, Johnston, Luke J, Derricott, Hayley, Armstrong, Stuart D, Randle, Nadine, Hartley, Catherine S, Duckworth, Carrie A, Campbell, Barry J, Wastling, Jonathan M, Coombes, Janine L

“…When transmitted through the oral route, first interacts with its host at the small intestinal epithelium. This interaction is crucial to controlling initial…”
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Longitudinal Associations of Phospholipid and Cholesteryl Ester Fatty Acids With Disorders Underlying Diabetes by Johnston, Luke W, Harris, Stewart B, Retnakaran, Ravi, Zinman, Bernard, Giacca, Adria, Liu, Zhen, Bazinet, Richard P, Hanley, Anthony J

“…Context: Specific serum fatty acid (FA) profiles predict the development of incident type 2 diabetes; however, limited longitudinal data exist exploring their…”
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Ostomy Usage for Colorectal Trauma in Combat Casualties by Johnston, Luke R., Bradley, Matthew J., Rodriguez, Carlos J., Mcnally, Michael P., Elster, Eric A., Duncan, James E.

“…Introduction The role for diverting ostomy as a method to help reduce morbidity and mortality has been well established in the combat trauma population…”
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