Search Results - "Johnston, Leland H"

In Vitro Regulation of Budding Yeast Bfa1/Bub2 GAP Activity by Cdc5 by Geymonat, Marco, Spanos, Ad, Walker, Philip A., Johnston, Leland H., Sedgwick, Steven G.

“…The Cdc5 protein of budding yeast is a polo-like kinase that has multiple roles in mitosis including control of the mitotic exit network (MEN). MEN activity…”
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Overlapping and distinct roles of the duplicated yeast transcription factors Ace2p and Swi5p by Doolin, Marie‐Therese, Johnson, Anthony L., Johnston, Leland H., Butler, Geraldine

“…The yeast transcription factors Ace2p and Swi5p regulate the expression of several target genes involved in mating type switching, exit from mitosis and cell…”
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The forkhead protein Fkh2 is a component of the yeast cell cycle transcription factor SFF by Pic, Aline, Lim, Fei-Ling, Ross, Sarah J., Veal, Elizabeth A., Johnson, Anthony L., Sultan, Mohammad R.A., West, Adam G., Johnston, Leland H., Sharrocks, Andrew D., Morgan, Brian A.

“…In the yeast Saccharomyces cerevisiae, the MADS‐box protein Mcm1, which is highly related to mammalian SRF (serum response factor), forms a ternary complex…”
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Complexity of Mitotic Exit by Jensen, Sanne, Johnston, Leland H.

“…Completion of mitosis in budding yeast is triggered by activation of the protein phosphatase Cdc14, which is the ultimate effector of a signalling cascade,…”
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The Spo12 Protein of Saccharomyces cerevisiae: A Regulator of Mitotic Exit Whose Cell Cycle-Dependent Degradation Is Mediated by the Anaphase-Promoting Complex by Shah, Rajvee, Jensen, Sanne, Frenz, Lisa M, Johnson, Anthony L, Johnston, Leland H

“…The Spo12 protein plays a regulatory role in two of the most fundamental processes of biology, mitosis and meiosis, and yet its biochemical function remains…”
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The Swi5 transcription factor of Saccharomyces cerevisiae has a role in exit from mitosis through induction of the cdk-inhibitor Sic1 in telophase by Toyn, J.H. (National Institute for Medical Research, London, UK.), Johnson, A.L, Donovan, J.D, Toone, W.M, Johnston, L.H

“…Deactivation of the B cylin kinase (Cdc28/Clb) drives the telophase to G1 cell cycle transition. Here we investigate one of the control pathways that…”
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Swi5 controls a novel wave of cyclin synthesis in late mitosis by Aerne, B L, Johnson, A L, Toyn, J H, Johnston, L H

“…We have shown previously that the Swi5 transcription factor regulates the expression of the SIC1 Cdk inhibitor in late mitosis. This suggests that Swi5 might…”
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Coordination of expression of DNA synthesis genes in budding yeast by a cell-cycle regulated trans factor by Lowndes, N.F, Johnson, A.L, Johnston, L.H

“…All of the DNA synthesis genes of budding yeast examined so far are periodically expressed and hence under cell-cycle control. Expression occurs near the G1/S…”
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Bub2p-dependent spindle checkpoint pathway regulates the Dbf2p kinase in budding yeast by Fesquet, D, Fitzpatrick, P.J, Johnson, A.L, Kramer, K.M, Toyn, J.H, Johnston, L.H

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GETTING STARTED:Regulating the Initiation of DNA Replication in Yeast by Toone, W. Mark, Aerne, Birgit L, Morgan, Brian A, Johnston, and Leland H

“…Initiation of DNA replication in yeast appears to operate through a two-step process. The first step occurs at the end of mitosis in the previous cell cycle,…”
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TPL-2 kinase regulates the proteolysis of the NF-κB-inhibitory protein NF-κB1 p105 by Ley, Steven C, Belich, Mônica P, Salmerón, Andrés, Johnston, Leland H

“…The transcription factor NF-κB is composed of homodimeric andheterodimeric complexes of Rel/NF-κB-family polypeptides, which include Rel-A, c-Rel, Rel-B,…”
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Control of mitotic exit in budding yeast. In vitro regulation of Tem1 GTPase by Bub2 and Bfa1 by Geymonat, Marco, Spanos, Ad, Smith, Susan J M, Wheatley, Edward, Rittinger, Katrin, Johnston, Leland H, Sedgwick, Steven G

“…The elimination of mitotic kinase activity at the end of mitosis is essential for progression to the next stage of the eukaryotic cell cycle. In budding yeast,…”
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The Skn7 response regulator of Saccharomyces cerevisiae interacts with Hsf1 in vivo and is required for the induction of heat shock genes by oxidative stress by Raitt, D C, Johnson, A L, Erkine, A M, Makino, K, Morgan, B, Gross, D S, Johnston, L H

“…The Skn7 response regulator has previously been shown to play a role in the induction of stress-responsive genes in yeast, e.g., in the induction of the…”
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Skn7 response regulator controls gene expression in the oxidative stress response of the budding yeast Saccharomyces cerevisiae by Morgan, B.A, Banks, G.R, Toone, W.M, Raitt, D, Kuge, S, Johnston, L.H

“…Deletion of the bacterial two-component response regulator homologue Skn7 results in sensitivity of yeast to oxidizing agents indicating that Skn7 is involved…”
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Spatial regulation of the guanine nucleotide exchange factor Lte1 in Saccharomyces cerevisiae by Jensen, Sanne, Geymonat, Marco, Johnson, Anthony L, Segal, Marisa, Johnston, Leland H

“…In budding yeast, activation of the small Ras-like GTPase Tem1 triggers exit from mitosis and cytokinesis. Tem1 is regulated by Bub2/Bfa1, a two-component…”
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yeast histidine protein kinase, Sln1p, mediates phosphotransfer to two response regulators, Ssk1p and Skn7p by Li, S, Ault, A, Malone, C.L, Raitt, D, Dean, S, Johnston, L.H, Deschenes, R.J, Fassler, J.S

“…The Saccharomyces cerevisiae Sln1 protein is a ‘two‐component’ regulator involved in osmotolerance. Two‐component regulators are a family of…”
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Mitotic Exit: The Cdc14 Double Cross by Geymonat, Marco, Jensen, Sanne, Johnston, Leland H

“…The release of Cdc14 from the nucleolus occurs in two waves in early and late anaphase, controlled by the FEAR and MEN pathways, respectively. Two new papers…”
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Characterization of the Yeast Cdc7p/Dbf4p Complex Purified from Insect Cells by Kihara, Makoto, Nakai, Wataru, Asano, Satoshi, Suzuki, Akiko, Kitada, Kunio, Kawasaki, Yasuo, Johnston, Leland H., Sugino, Akio

“…The yeast Saccharomyces cerevisiaeCdc7p/Dbf4p protein kinase complex was purified to near homogeneity from insect cells. The complex efficiently phosphorylated…”
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The mitotic exit network by Bettignies, Geoffroy de, Johnston, Leland H.

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A Bub2p‐dependent spindle checkpoint pathway regulates the Dbf2p kinase in budding yeast by Fesquet, Didier, Fitzpatrick, Patrick J., Johnson, Anthony L., Kramer, Kate M., Toyn, Jeremy H., Johnston, Leland H.

“…Exit from mitosis in all eukaroytes requires inactivation of the mitotic kinase. This occurs principally by ubiquitin‐mediated proteolysis of the cyclin…”
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