Search Results - "Johnston, Laura K"

The immunology of food allergy by Johnston, Laura K, Chien, Karen B, Bryce, Paul J

“…Food allergies represent an increasingly prevalent human health problem, and therapeutic options remain limited, with avoidance being mainstay, despite its…”
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Pulmonary macrophage subpopulations in the induction and resolution of acute lung injury by Johnston, Laura K, Rims, Cliff R, Gill, Sean E, McGuire, John K, Manicone, Anne M

“…Macrophages are key orchestrators of the inflammatory and repair responses in the lung, and the diversity of their function is indicated by their polarized…”
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IL-33 Precedes IL-5 in Regulating Eosinophil Commitment and Is Required for Eosinophil Homeostasis by Johnston, Laura K, Hsu, Chia-Lin, Krier-Burris, Rebecca A, Chhiba, Krishan D, Chien, Karen B, McKenzie, Andrew, Berdnikovs, Sergejs, Bryce, Paul J

“…Eosinophils are important in the pathogenesis of many diseases, including asthma, eosinophilic esophagitis, and eczema. Whereas IL-5 is crucial for supporting…”
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MMP28 promotes macrophage polarization toward M2 cells and augments pulmonary fibrosis by Gharib, Sina A., Johnston, Laura K., Huizar, Isham, Birkland, Timothy P., Hanson, Josiah, Wang, Ying, Parks, William C., Manicone, Anne M.

“…MMP28 promotes alternatively activated (M2) macrophage function, and regulates the fibrotic response in the lung. Members of the MMP family function in various…”
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TGF-β1 limits the onset of innate lung inflammation by promoting mast cell-derived IL-6 by Ganeshan, Kirthana, Johnston, Laura K, Bryce, Paul J

“…TGF-β1 is an important suppressive mediator of inflammation, but it can also drive fibrosis and remodeling in the lung. In response to intratracheal LPS,…”
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Understanding Interleukin 33 and Its Roles in Eosinophil Development by Johnston, Laura K, Bryce, Paul J

“…Over the last decade, significant interest in the contribution of three "epithelial-derived cytokines," such as thymic stromal lymphopoietin, interleukin 25,…”
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Epilysin (matrix metalloproteinase-28) contributes to airway epithelial cell survival by Manicone, Anne M, Harju-Baker, Susanna, Johnston, Laura K, Chen, Ann J, Parks, William C

“…MMP28 is constitutively expressed by epithelial cells in many tissues, including the respiratory epithelium in the lung and keratinocytes in the skin. This…”
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Diet-induced obesity alters myeloid cell populations in naïve and injured lung by Manicone, Anne M, Gong, Keqin, Johnston, Laura K, Giannandrea, Matthew

“…There are pulmonary consequences to obesity, including increased prevalence of asthma, greater susceptibility to influenza, and possibly reduced susceptibility…”
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Donor leukocyte trafficking during human ex vivo lung perfusion by Lee, Andy Chao Hsuan, Edobor, Arianna, Wigakumar, Thirushan, Lysandrou, Maria, Johnston, Laura K., McMullen, Phillip, Mirle, Vikranth, Diaz, Ashley, Piech, Ryan, Rose, Rebecca, Jendrisak, Martin, di Sabato, Diego, Shanmugarajah, Kumaran, Fung, John, Donington, Jessica, Madariaga, Maria Lucia

“…Background Ex vivo lung perfusion (EVLP) is used to assess and preserve lungs prior to transplantation. However, its inherent immunomodulatory effects are not…”
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IL-33 promotes gastrointestinal allergy in a TSLP-independent manner by Han, H, Roan, F, Johnston, L K, Smith, D E, Bryce, P J, Ziegler, S F

“…Atopic dermatitis (AD) often precedes asthma and food allergy, indicating that epicutaneous sensitization to allergens may be important in the induction of…”
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The Immunology of Food Allergy1 by Johnston, Laura K., Chien, Karen B., Bryce, Paul J.

“…Food allergies represent an increasingly prevalent human health problem and therapeutic options remain limited, with avoidance being mainstay despite its…”
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TGF- beta 1 Limits the Onset of Innate Lung Inflammation by Promoting Mast Cell-Derived IL-6 by Ganeshan, Kirthana, Johnston, Laura K, Bryce, Paul J

“…TGF- beta 1 is an important suppressive mediator of inflammation, but it can also drive fibrosis and remodeling in the lung. In response to intratracheal LPS,…”
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TGFβ1 limits the onset of innate lung inflammation by promoting mast cell-derived IL-61 by Ganeshan, Kirthana, Johnston, Laura K., Bryce, Paul J.

“…TGFβ1 is an important suppressive mediator of inflammation but can also drive fibrosis and remodeling in the lung. In response to intratracheal LPS,…”
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Eosinophil lineage commitment and IL-5-dependent expansion is regulated by IL-33 in mice by Johnston, Laura K, Hsu, Chia-Lin, Krier-Burris, Rebecca A., Chhiba, Krishan D., Chien, Karen B., McKenzie, Andrew, Berdnikovs, Sergejs, Bryce, Paul J.

“…Abstract Eosinophils are important in the pathogenesis of many diseases, including asthma, eosinophilic esophagitis and eczema. While IL-5 is necessary for the…”
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