Search Results - "Johnson, William M"

Dysregulation of glutathione homeostasis in neurodegenerative diseases by Johnson, William M, Wilson-Delfosse, Amy L, Mieyal, John J

“…Dysregulation of glutathione homeostasis and alterations in glutathione-dependent enzyme activities are increasingly implicated in the induction and…”
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Nerve Growth Factor Regulates Transient Receptor Potential Vanilloid 2 via Extracellular Signal-Regulated Kinase Signaling To Enhance Neurite Outgrowth in Developing Neurons by Cohen, Matthew R., Johnson, William M., Pilat, Jennifer M., Kiselar, Janna, DeFrancesco-Lisowitz, Alicia, Zigmond, Richard E., Moiseenkova-Bell, Vera Y.

“…Neurite outgrowth is key to the formation of functional circuits during neuronal development. Neurotrophins, including nerve growth factor (NGF), increase…”
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Regulation of DJ‑1 by Glutaredoxin 1 in Vivo: Implications for Parkinson’s Disease by Johnson, William M, Golczak, Marcin, Choe, Kyonghwan, Curran, Pierce L, Miller, Olga Gorelenkova, Yao, Chen, Wang, Wenzhang, Lin, Jiusheng, Milkovic, Nicole M, Ray, Ajit, Ravindranath, Vijayalakshmi, Zhu, Xiongwei, Wilson, Mark A, Wilson-Delfosse, Amy L, Chen, Shu G, Mieyal, John J

“…Parkinson’s disease (PD) is the second most common neurodegenerative disease worldwide, caused by the degeneration of the dopaminergic neurons in the…”
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Glutaredoxin deficiency exacerbates neurodegeneration in C. elegans models of Parkinson's disease by Johnson, William M., Yao, Chen, Siedlak, Sandra L., Wang, Wenzhang, Zhu, Xiongwei, Caldwell, Guy A., Wilson-Delfosse, Amy L., Mieyal, John J., Chen, Shu G.

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Composition of Exfoliation Material by Challa, Pratap, Johnson, William M

“…Exfoliation glaucoma (XFG) is the most common identifiable cause of open-angle glaucoma worldwide, and results from the accumulation of extracellular…”
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Major review: Exfoliation syndrome; advances in disease genetics, molecular biology, and epidemiology by Aboobakar, Inas F., Johnson, William M., Stamer, W. Daniel, Hauser, Michael A., Allingham, R. Rand

“…Exfoliation syndrome (XFS) is a common age-related disorder that leads to deposition of extracellular fibrillar material throughout the body. The most…”
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Expression of mRNAs, miRNAs, and lncRNAs in Human Trabecular Meshwork Cells Upon Mechanical Stretch by Youngblood, Hannah, Cai, Jingwen, Drewry, Michelle D, Helwa, Inas, Hu, Eric, Liu, Sabrina, Yu, Hongfang, Mu, Hongmei, Hu, Yanzhong, Perkumas, Kristin, Aboobakar, Inas F, Johnson, William M, Stamer, W Daniel, Liu, Yutao

“…Intraocular pressure (IOP), the primary risk factor for primary open-angle glaucoma, is determined by resistance to aqueous outflow through the trabecular…”
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Integral role for lysyl oxidase‐like‐1 in conventional outflow tissue function and behavior by Li, Guorong, Schmitt, Heather, Johnson, William M., Lee, Chanyoung, Navarro, Iris, Cui, Jenny, Fleming, Todd, Gomez‐Caraballo, María, Elliott, Michael H., Sherwood, Joseph M., Hauser, Michael A., Farsiu, Sina, Ethier, C. Ross, Stamer, W. Daniel

“…Lysyl oxidase‐like‐1 (LOXL1), a vital crosslinking enzyme in elastin fiber maintenance, is essential for the stability and strength of elastic vessels and…”
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Lysyl oxidase-like 1-antisense 1 (LOXL1-AS1) lncRNA differentially regulates gene and protein expression, signaling and morphology of human ocular cells by Schmitt, Heather M, Hake, Kristyn M, Perkumas, Kristin M, Lê, Brandon M, Suarez, Maria F, De Ieso, Michael L, Rahman, Rashad S, Johnson, William M, Gomez-Caraballo, María, Ashley-Koch, Allison E, Hauser, Michael A, Stamer, W Daniel

“…Pseudoexfoliation glaucoma (PEXG) is characterized by dysregulated extracellular matrix (ECM) homeostasis that disrupts conventional outflow function and…”
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Prion protein modulates endothelial to mesenchyme-like transition in trabecular meshwork cells: Implications for primary open angle glaucoma by Ashok, Ajay, Kang, Min H., Wise, Aaron S., Pattabiraman, P., Johnson, William M., Lonigro, Michael, Ravikumar, Ranjana, Rhee, Douglas J., Singh, Neena

“…Endothelial-to-mesenchyme-like transition (Endo-MT) of trabecular meshwork (TM) cells is known to be associated with primary open angle glaucoma (POAG). Here,…”
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Identification and activity of the functional complex between hnRNPL and the pseudoexfoliation syndrome-associated lncRNA, LOXL1-AS1 by Schmitt, Heather M, Johnson, William M, Aboobakar, Inas F, Strickland, Shelby, Gomez-Caraballo, María, Parker, Megan, Finnegan, Laura, Corcoran, David L, Skiba, Nikolai P, Allingham, R Rand, Hauser, Michael A, Stamer, W Daniel

“…Abstract Individuals with pseudoexfoliation (PEX) syndrome exhibit various connective tissue pathologies associated with dysregulated extracellular matrix…”
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Serum levels of lipid metabolites in age‐related macular degeneration by Orban, Tivadar, Johnson, William M., Dong, Zhiqian, Maeda, Tadao, Maeda, Akiko, Sakai, Tsutomu, Tsuneoka, Hiroshi, Mieyal, John J., Palczewski, Krzysztof

“…ABSTRACT Age‐related macular degeneration (AMD) is a neurodegenerative disease that causes adult‐onset blindness. There are 2 forms of this progressive…”
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Mediterranean monk seal Monachus monachus: status, biology, threats, and conservation priorities by Karamanlidis, Alexandros A., Dendrinos, Panagiotis, de Larrinoa, Pablo Fernández, Gücü, Ali Cemal, Johnson, William M., Kiraç, Cem O., Pires, Rosa

“…The Mediterranean monk seal Monachus monachus is the most endangered seal species. In this review we summarize the status, ecology, and behaviour of the…”
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lncRNAs, DNA Methylation, and the Pathobiology of Exfoliation Glaucoma by Johnson, William M, Finnegan, Laura K, Hauser, Michael A, Stamer, W Daniel

“…Exfoliation glaucoma (XFG) is a clinically aggressive and genetically distinct form of glaucoma that results in neuronal death and irreversible blindness. Gene…”
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Kinase inhibitors arrest neurodegeneration in cell and C. elegans models of LRRK2 toxicity by Yao, Chen, Johnson, William M, Gao, Yue, Wang, Wen, Zhang, Jinwei, Deak, Maria, Alessi, Dario R, Zhu, Xiongwei, Mieyal, John J, Roder, Hanno, Wilson-Delfosse, Amy L, Chen, Shu G

“…Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most frequent known cause of late-onset Parkinson's disease (PD). To explore the therapeutic…”
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Glutaredoxin deficiency exacerbates neurodegeneration in C. elegans models of Parkinson's disease by Johnson, William M, Yao, Chen, Siedlak, Sandra L, Wang, Wenzhang, Zhu, Xiongwei, Caldwell, Guy A, Wilson-Delfosse, Amy L, Mieyal, John J, Chen, Shu G

“…Parkinson's disease (PD) is characterized by selective degeneration of dopaminergic neurons. Although the etiology of PD remains incompletely understood,…”
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Motor and non-motor features of Parkinson's disease in LRRK2 G2019S carriers versus matched controls by Gunzler, Steven A., Riley, David E., Chen, Shu G., Tatsuoka, Curtis M., Johnson, William M., Mieyal, John J., Walter, Ellen M., Whitney, Christina M., Feng, I. Jung, Owusu-Dapaah, Harry, Mittal, Shivam O., Wilson-Delfosse, Amy L.

“…LRRK2 G2019S mutation carriers with Parkinson's disease (PD) have been generally indistinguishable from those with idiopathic PD, with the exception of…”
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Primary lung large cell carcinoma metastatic to the vulva: a case report and review of the literature by Rocconi, Rodney P., Leath, Charles A., Johnson, William M., Barnes, Mack N., Conner, Michael G.

“…Background. Metastatic cancer to the vulva is a rare diagnosis and is estimated to account for 5–8% of all vulvar cancers. Case. A 57-year-old postmenopausal…”
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Double jeopardy: lung cancer after cardiac transplantation by Johnson, W M, Baldursson, O, Gross, T J

“…Two heart transplant patients were referred on the same day for evaluation of new chest radiograph abnormalities. Each proved to have advanced stage…”
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Trends over time among cotton cultivars released by the Oklahoma Agricultural Experiment Station by Bayles, M.B, Verhalen, L.M, Johnson, W.M, Barnes, B.R

“…Twelve cotton (Gossypium hirsutum L.) cultivars, released by the Oklahoma Agricultural Experiment Station (OAES) between 1918 and 1982 inclusive, were…”
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