Search Results - "Johnson, Sherika"
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Therapeutic Trem2 activation ameliorates amyloid-beta deposition and improves cognition in the 5XFAD model of amyloid deposition
Published in Journal of neuroinflammation (14-08-2020)“…Triggering receptor expressed on myeloid cell-2 (TREM2) is a lipid and lipoprotein binding receptor expressed by cells of myeloid origin. Homozygous TREM2…”
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Atorvastatin rescues hyperhomocysteinemia-induced cognitive deficits and neuroinflammatory gene changes
Published in Journal of neuroinflammation (01-09-2023)“…Epidemiological data suggests statins could reduce the risk of dementia, and more specifically, Alzheimer's disease (AD). Pre-clinical data suggests statins…”
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TNFα‐mediated inflammation in mouse models of VCID
Published in Alzheimer's & dementia (01-12-2023)“…Background Tumor necrosis factor alpha (TNFα) is a prominent pleiotropic cytokine with dichotomous effects. Primarily produced in the brain by glial cells,…”
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Journal Article