Search Results - "Johnson, Paul C. D."
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The coefficient of determination R2 and intra-class correlation coefficient from generalized linear mixed-effects models revisited and expanded
Published in Journal of the Royal Society interface (01-09-2017)“…The coefficient of determination R2 quantifies the proportion of variance explained by a statistical model and is an important summary statistic of biological…”
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2
Rapid age-grading and species identification of natural mosquitoes for malaria surveillance
Published in Nature communications (21-03-2022)“…The malaria parasite, which is transmitted by several Anopheles mosquito species, requires more time to reach its human-transmissible stage than the average…”
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High Dose Atorvastatin Associated with Increased Risk of Significant Hepatotoxicity in Comparison to Simvastatin in UK GPRD Cohort
Published in PloS one (16-03-2016)“…Occasional risk of serious liver dysfunction and autoimmune hepatitis during atorvastatin therapy has been reported. We compared the risk of hepatotoxicity in…”
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4
Heritability of biting time behaviours in the major African malaria vector Anopheles arabiensis
Published in Malaria journal (16-08-2023)“…The use of insecticide-treated nets for malaria control has been associated with shifts in mosquito vector feeding behaviour including earlier and outdoor…”
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High Temperature Cycles Result in Maternal Transmission and Dengue Infection Differences Between Wolbachia Strains in Aedes aegypti
Published in mBio (21-12-2021)“…Environmental factors play a crucial role in the population dynamics of arthropod endosymbionts, and therefore in the deployment of symbionts for the control…”
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Evaluating the potential of whole-genome sequencing for tracing transmission routes in experimental infections and natural outbreaks of bovine respiratory syncytial virus
Published in Veterinary research (Paris) (12-12-2022)“…Bovine respiratory syncytial virus (BRSV) is a major cause of respiratory disease in cattle. Genomic sequencing can resolve phylogenetic relationships between…”
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Association Between Genetic Variants on Chromosome 15q25 Locus and Objective Measures of Tobacco Exposure
Published in JNCI : Journal of the National Cancer Institute (16-05-2012)“…Two single-nucleotide polymorphisms, rs1051730 and rs16969968, located within the nicotinic acetylcholine receptor gene cluster on chromosome 15q25 locus, are…”
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The antiviral state has shaped the CpG composition of the vertebrate interferome to avoid self-targeting
Published in PLoS biology (07-09-2021)“…Antiviral defenses can sense viral RNAs and mediate their destruction. This presents a challenge for host cells since they must destroy viral RNAs while…”
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Maximum-Likelihood Estimation of Allelic Dropout and False Allele Error Rates From Microsatellite Genotypes in the Absence of Reference Data
Published in Genetics (Austin) (01-02-2007)“…The importance of quantifying and accounting for stochastic genotyping errors when analyzing microsatellite data is increasingly being recognized. This…”
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10
Master statistical analysis plan: attractive targeted sugar bait phase III trials in Kenya, Mali, and Zambia
Published in Current controlled trials in cardiovascular medicine (29-11-2023)“…Abstract This manuscript is a master statistical analysis plan for each of three-cluster randomized controlled trials to evaluate the efficacy of attractive…”
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Accelerated telomere attrition is associated with relative household income, diet and inflammation in the pSoBid cohort
Published in PloS one (27-07-2011)“…It has previously been hypothesized that lower socio-economic status can accelerate biological ageing, and predispose to early onset of disease. This study…”
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12
Virus–virus interactions impact the population dynamics of influenza and the common cold
Published in Proceedings of the National Academy of Sciences - PNAS (26-12-2019)“…The human respiratory tract hosts a diverse community of cocirculating viruses that are responsible for acute respiratory infections. This shared niche…”
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Inter-epidemic Rift Valley fever virus infection incidence and risks for zoonotic spillover in northern Tanzania
Published in PLoS neglected tropical diseases (28-10-2022)“…Rift Valley fever virus (RVFV) is a mosquito-borne pathogen that has caused epidemics involving people and animals across Africa and the Arabian Peninsula. A…”
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Towards the elimination of dog-mediated rabies: development and application of an evidence-based management tool
Published in BMC infectious diseases (20-10-2020)“…International organizations advocate for the elimination of dog-mediated rabies, but there is only limited guidance on interpreting surveillance data for…”
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HLA-A alleles and infectious mononucleosis suggest a critical role for cytotoxic T-cell response in EBV-related Hodgkin lymphoma
Published in Proceedings of the National Academy of Sciences - PNAS (06-04-2010)“…A proportion of classical Hodgkin lymphoma (HL) is believed to be causally related to infection with the ubiquitous lymphotropic EBV. The determining factors…”
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Intergenerational change and familial aggregation of body mass index
Published in European journal of epidemiology (01-01-2012)“…The relationship between parental BMI and that of their adult offspring, when increased adiposity can become a clinical issue, is unknown. We investigated the…”
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Aging partially restores the efficacy of malaria vector control in insecticide-resistant populations of Anopheles gambiae s.l. from Burkina Faso
Published in Malaria journal (23-01-2012)“…The operational impact of insecticide resistance on the effectiveness of long-lasting insecticide nets (LLINs) and indoor residual spraying (IRS) is poorly…”
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18
Multiple lineages of lice pass through the K–Pg boundary
Published in Biology letters (2005) (23-10-2011)“…For modern lineages of birds and mammals, few fossils have been found that predate the Cretaceous–Palaeogene (K–Pg) boundary. However, molecular studies using…”
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Classification and characterisation of livestock production systems in northern Tanzania
Published in PloS one (30-12-2020)“…Livestock keepers in sub-Saharan Africa face a range of pressures, including climate change, land loss, restrictive policies, and population increase…”
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Digital gene expression analysis of two life cycle stages of the human-infective parasite, Trypanosoma brucei gambiense reveals differentially expressed clusters of co-regulated genes
Published in BMC genomics (22-02-2010)“…The evolutionarily ancient parasite, Trypanosoma brucei, is unusual in that the majority of its genes are regulated post-transcriptionally, leading to the…”
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