Search Results - "Johnson, P V"

Intestinal alkaline phosphatase preserves the normal homeostasis of gut microbiota by Malo, M S, Alam, S Nasrin, Mostafa, G, Zeller, S J, Johnson, P V, Mohammad, N, Chen, K T, Moss, A K, Ramasamy, S, Faruqui, A, Hodin, S, Malo, P S, Ebrahimi, F, Biswas, B, Narisawa, S, Millán, J L, Warren, H S, Kaplan, J B, Kitts, C L, Hohmann, E L, Hodin, R A

“…The intestinal microbiota plays a critical role in maintaining human health; however, the mechanisms governing the normal homeostatic number and composition of…”
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long lifespan and low turnover of human islet beta cells estimated by mathematical modelling of lipofuscin accumulation by Cnop, M, Hughes, S. J, Igoillo-Esteve, M, Hoppa, M. B, Sayyed, F, van de Laar, L, Gunter, J. H, de Koning, E. J. P, Walls, G. V, Gray, D. W. G, Johnson, P. R. V, Hansen, B. C, Morris, J. F, Pipeleers-Marichal, M, Cnop, I, Clark, A

“…Aims/hypothesis Defects in pancreatic beta cell turnover are implicated in the pathogenesis of type 2 diabetes by genetic markers for diabetes. Decreased beta…”
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Regulation of glucagon secretion by glucose: paracrine, intrinsic or both? by Walker, J. N., Ramracheya, R., Zhang, Q., Johnson, P. R. V., Braun, M., Rorsman, P.

“…Glucagon secretion is regulated by glucose but the mechanisms involved remain hotly debated. Both intrinsic (within the α‐cell itself) and paracrine (mediated…”
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Glucose-responsive beta cells in islets isolated from a patient with long-standing type 1 diabetes mellitus by Walker, J. N., Johnson, P. R. V., Shigeto, M., Hughes, S. J., Clark, A., Rorsman, P.

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Contemporary management and outcomes for infants born with oesophageal atresia by Burge, D. M., Shah, K., Spark, P., Shenker, N., Pierce, M., Kurinczuk, J. J., Draper, E. S., Johnson, P. R. V., Knight, M.

“…Background: Reports on the management and outcome of rare conditions, such as oesophageal atresia, are frequently limited to case series reporting…”
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Vascular endothelial growth factor as a survival factor for human islets: effect of immunosuppressive drugs by Cross, S. E, Richards, S. K, Clark, A, Benest, A. V, Bates, D. O, Mathieson, P. W, Johnson, P. R. V, Harper, S. J, Smith, R. M

“…Aims/hypothesis Rapamycin, part of the immunosuppressive regimen of the Edmonton protocol, has been shown to inhibit vascular endothelial growth factor (VEGF)…”
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Cross sections for the O II (83.4 nm) emission from electron impact on O2 by Malone, C. P., Johnson, P. V., McConkey, J. W., Kanik, I.

“…Vacuum ultraviolet emissions resulting from electron impact on O2 have been studied at 100, 200, and 300 eV. The ratio of the 83.4 nm and 130.4 nm emissions…”
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Electron impact dissociation of oxygen-containing molecules–A critical review by McConkey, J.W., Malone, C.P., Johnson, P.V., Winstead, C., McKoy, V., Kanik, I.

“…The dissociation of a wide range of oxygen-containing molecules following impact with electrons of carefully controlled energy is critically reviewed…”
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Magnetic Resonance Imaging of Brain Anomalies in Fetal Alcohol Syndrome by Swayze, Victor W., II, Johnson, Virginia P, Hanson, James W, Piven, Joseph, Sato, Yutaka, Giedd, Jay N, Mosnik, Diane, Andreasen, Nancy C

“…Postmortem studies of fetuses, infants, and young children with fetal alcohol syndrome (FAS) have demonstrated a variety of severe central nervous system (CNS)…”
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Perfluorocarbon emulsions prevent hypoxia of pancreatic β-cells by Maillard, E, Juszczak, M T, Langlois, A, Kleiss, C, Sencier, M C, Bietiger, W, Sanchez-Dominguez, M, Krafft, M P, Johnson, P R V, Pinget, M, Sigrist, S

“…As oxygen carriers, perfluorocarbon emulsions might be useful to decrease hypoxia of pancreatic islets before transplantation. However, their hydrophobicity…”
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Electron impact study of the 100 eV emission cross section and lifetime of the Lyman‐Birge‐Hopfield band system of N2: Direct excitation and cascade by Ajello, J. M., Malone, C. P., Holsclaw, G. M., Hoskins, A. C., Eastes, R. W., McClintock, W. E., Johnson, P. V.

“…We have measured the 100 eV emission cross section of the optically forbidden Lyman‐Birge‐Hopfield (LBH) band system (a1Πg → X1Σ+g) of N2 by…”
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Durability of deaired brick by Mcburney, J . W., Johnson, P. V.

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Correlation of severity and outcome with plasma sterol levels in variants of the Smith-Lemli-Opitz syndrome by Tint, G.S., Salen, Gerald, Batta, Ashok K., Shefer, Sarah, Irons, Mira, Elias, Ellen Roy, Abuelo, Dianne N., Johnson, Virginia P., Lambert, Marie, Lutz, Richard, Schanen, Carolyn, Morris, Colleen A., Hoganson, George, Hughes-Benzie, Rhiannon

“…Objectives: To determine whether type I and the more severe type II variant of Smith-Lemli-Opitz syndrome have the same metabolic defect and to learn which…”
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Optimal regulatory control of early contract termination by Evatt, G. W., Johnson, P. V., Duck, P. W.

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Linkage of a Human Brain Malformation, Familial Holoprosencephaly, to Chromosome 7 and Evidence for Genetic Heterogeneity by Muenke, Maximilian, Gurrieri, Fiorella, Bay, Carolyn, Yi, David H., Collins, Amanda L., Johnson, Virginia P., Raoul C. M. Hennekam, Schaefer, G. Bradley, Weik, LuAnn, Lubinsky, Mark S., Daack-Hirsch, Sandy, Moore, Cynthia A., Dobyns, William B., Murray, Jeffrey C., Price, R. Arlen

“…Holoprosencephaly (HPE) is a common malformation of the developing forebrain and midface characterized by incomplete penetrance and variable expressivity…”
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Key Matrix Proteins Within the Pancreatic Islet Basement Membrane Are Differentially Digested During Human Islet Isolation by Cross, S. E., Vaughan, R. H., Willcox, A. J., McBride, A. J., Abraham, A. A., Han, B., Johnson, J. D., Maillard, E., Bateman, P. A., Ramracheya, R. D., Rorsman, P., Kadler, K. E., Dunne, M. J., Hughes, S. J., Johnson, P. R. V.

“…Clinical islet transplantation achieves insulin independence in selected patients, yet current methods for extracting islets from their surrounding pancreatic…”
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The detection of contiguous gene deletions at the neurofibromatosis 1 locus with fluorescence in situ hybridization by Leppig, K A, Viskochil, D, Neil, S, Rubenstein, A, Johnson, V P, Zhu, X L, Brothman, A R, Stephens, K

“…Neurofibromatosis type 1 (NF1) is a common genetic disorder characterized primarily by the development of multiple neurofibromas and pigmentary changes. The…”
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Altered Phenotype of β-Cells and Other Pancreatic Cell Lineages in Patients With Diffuse Congenital Hyperinsulinism in Infancy Caused by Mutations in the ATP-Sensitive K-Channel by Salisbury, Rachel J, Han, Bing, Jennings, Rachel E, Berry, Andrew A, Stevens, Adam, Mohamed, Zainab, Sugden, Sarah A, De Krijger, Ronald, Cross, Sarah E, Johnson, Paul P V, Newbould, Melanie, Cosgrove, Karen E, Hanley, Karen Piper, Banerjee, Indraneel, Dunne, Mark J, Hanley, Neil A

“…Diffuse congenital hyperinsulinism in infancy (CHI-D) arises from mutations inactivating the KATP channel; however, the phenotype is difficult to explain from…”
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Effect of Etanercept Concentration on Human Islet Integrity by Acreman, S., Brandhorst, H., Abraham, A., Johnson, P.R.V., Brandhorst, D.

“…Etanercept is widely used as an antiinflammatory drug to improve engraftment after intraportal islet transplantation. In contrast to other immunosuppressive…”
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Hypoxia-Induced Damage in Human Islets Is Reduced With the Use of Mesenchymal Stem Cell–Preconditioned Medium by Brandhorst, D., Brandhorst, H., Acreman, S., Schive, S.W., Bjørnson Scholz, H., Johnson, P.R.V.

“…Mesenchymal stem cells (MSCs) are protective for islets when cotransplanted in a hypoxic environment. However, the risk of neoplasia is increased when MSCs are…”
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