Search Results - "Johnson, Nicholas A."

Recent Developments in the Medicinal Applications of Silver-NHC Complexes and Imidazolium Salts by Johnson, Nicholas A, Southerland, Marie R, Youngs, Wiley J

“…Because of their great structural diversity and multitude of chemical properties, N-heterocyclic carbenes (NHCs) have been utilized in a variety of capacities…”
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Subtelomeric 5-enolpyruvylshikimate-3-phosphate synthase copy number variation confers glyphosate resistance in Eleusine indica by Zhang, Chun, Johnson, Nicholas A., Hall, Nathan, Tian, Xingshan, Yu, Qin, Patterson, Eric L.

“…Genomic structural variation (SV) has profound effects on organismal evolution; often serving as a source of novel genetic variation. Gene copy number…”
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How inclusive were UK-based randomised controlled trials of COVID-19 vaccines? A systematic review investigating enrolment of Black adults and adult ethnic minorities by Herieka, Hibba, Babalis, Daphne, Tzala, Evangelia, Budhathoki, Shyam, Johnson, Nicholas A

“…To establish if Black adults and adult ethnic minorities, defined as any group except White British, were represented in UK-based COVID-19 vaccination…”
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Genetic architecture of skin and eye color in an African-European admixed population by Beleza, Sandra, Johnson, Nicholas A, Candille, Sophie I, Absher, Devin M, Coram, Marc A, Lopes, Jailson, Campos, Joana, Araújo, Isabel Inês, Anderson, Tovi M, Vilhjálmsson, Bjarni J, Nordborg, Magnus, Correia E Silva, António, Shriver, Mark D, Rocha, Jorge, Barsh, Gregory S, Tang, Hua

“…Variation in human skin and eye color is substantial and especially apparent in admixed populations, yet the underlying genetic architecture is poorly…”
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Evidence of unexplained discrepancies between planned and conducted statistical analyses: a review of randomised trials by Cro, Suzie, Forbes, Gordon, Johnson, Nicholas A, Kahan, Brennan C

“…Choosing or altering the planned statistical analysis approach after examination of trial data (often referred to as 'p-hacking') can bias the results of…”
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Ancestral components of admixed genomes in a Mexican cohort by Johnson, Nicholas A, Coram, Marc A, Shriver, Mark D, Romieu, Isabelle, Barsh, Gregory S, London, Stephanie J, Tang, Hua

“…For most of the world, human genome structure at a population level is shaped by interplay between ancient geographic isolation and more recent demographic…”
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Genome-wide Characterization of Shared and Distinct Genetic Components that Influence Blood Lipid Levels in Ethnically Diverse Human Populations by Coram, Marc A., Duan, Qing, Hoffmann, Thomas J., Thornton, Timothy, Knowles, Joshua W., Johnson, Nicholas A., Ochs-Balcom, Heather M., Donlon, Timothy A., Martin, Lisa W., Eaton, Charles B., Robinson, Jennifer G., Risch, Neil J., Zhu, Xiaofeng, Kooperberg, Charles, Li, Yun, Reiner, Alex P., Tang, Hua

“…Blood lipid concentrations are heritable risk factors associated with atherosclerosis and cardiovascular diseases. Lipid traits exhibit considerable variation…”
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Genetic markers of ovarian follicle number and menopause in women of multiple ethnicities by Schuh-Huerta, Sonya M., Johnson, Nicholas A., Rosen, Mitchell P., Sternfeld, Barbara, Cedars, Marcelle I., Reijo Pera, Renee A.

“…Oocyte loss has a significant impact on fertility and somatic health. Yet, we know little about factors that impact this process. We sought to identify genetic…”
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Does Bypass of the Proximal Small Intestine Impact Food Intake, Preference, and Taste Function in Humans? An Experimental Medicine Study Using the Duodenal-Jejunal Bypass Liner by Aldhwayan, Madhawi M, Al-Najim, Werd, Ruban, Aruchuna, Glaysher, Michael Alan, Johnson, Brett, Chhina, Navpreet, Dimitriadis, Georgios K, Prechtl, Christina Gabriele, Johnson, Nicholas A, Byrne, James Patrick, Goldstone, Anthony Peter, Teare, Julian P, Le Roux, Carel W, Miras, Alexander Dimitri

“…The duodenal-jejunal bypass liner (Endobarrier) is an endoscopic treatment for obesity and type 2 diabetes mellitus (T2DM). It creates exclusion of the…”
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A Source‐Sink Hypothesis for Abyssal Biodiversity by Rex, Michael A., McClain, Craig R., Johnson, Nicholas A., Etter, Ron J., Allen, John A., Bouchet, Philippe, Warén, Anders

“…Bathymetric gradients of biodiversity in the deep‐sea benthos constitute a major class of large‐scale biogeographic phenomena. They are typically portrayed and…”
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Compressed sensing: a discrete optimization approach by Bertsimas, Dimitris, Johnson, Nicholas A. G.

“…We study the Compressed Sensing (CS) problem, which is the problem of finding the most sparse vector that satisfies a set of linear measurements up to some…”
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Joint testing of genotype and ancestry association in admixed families by Tang, Hua, Siegmund, David O., Johnson, Nicholas A., Romieu, Isabelle, London, Stephanie J.

“…Current genome‐wide association studies (GWAS) often involve populations that have experienced recent genetic admixture. Genotype data generated from these…”
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Investigation of Phosphazene Superbase Interactions with [PCl2N]3 by Johnson, Nicholas A., Xue, Yuan, Panzner, Matthew J., Youngs, Wiley J., Tessier, Claire A.

“…In this study, the reaction between phosphazene superbases and a chlorophosphazene trimer ([PCl2N]3) has been investigated. In this room temperature reaction,…”
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ROptimus: a parallel general-purpose adaptive optimization engine by Johnson, Nicholas A G, Tamon, Liezel, Liu, Xin, Sahakyan, Aleksandr B

“…Summary Motivation Various computational biology calculations require a probabilistic optimization protocol to determine the parameters that capture the system…”
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ACCURATE CONSTRUCTION OF LONG RANGE HAPLOTYPE IN UNRELATED INDIVIDUALS by Johnson, Nicholas A, London, Stephanie J., Romieu, Isabelle, Wong, Wing H., Tang, Hua

“…Haplotype, or the sequence of alleles along a single chromosome, has important applications in phenotype-genotype association studies, as well as in population…”
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The Use of Optical Coherence Tomography for Early Glaucoma Screening in a Population of Patients with Diabetes by Johnson, Nicholas A., Gupta, Priya, Lee, Terry, Hadziahmetovic, Majda, Rosdahl, Jullia A.

“…The utility of screening for early diagnosis of glaucoma remains a widely debated topic in the care of ophthalmic patients. There are currently no…”
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The Effect of Bimatoprost Implant on Glaucoma Patients: An Observational Study by Choi, Eun Young, Johnson, Nicholas A, Stinnett, Sandra, Rosdahl, Jullia, Moya, Frank, Herndon, Leon W

“…In this retrospective study of glaucoma patients receiving the bimatoprost implant at Duke Eye Center, the number of topical intraocular pressure-lowering…”
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Genetic variants and environmental factors associated with hormonal markers of ovarian reserve in Caucasian and African American women by Schuh-Huerta, Sonya M., Johnson, Nicholas A., Rosen, Mitchell P., Sternfeld, Barbara, Cedars, Marcelle I., Reijo Pera, Renee A.

“…BACKGROUND The ovarian reserve (number and quality of oocytes) is correlated with reproductive potential as well as somatic health, and is likely to have…”
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Genome-wide association study of body height in African Americans: the Women's Health Initiative SNP Health Association Resource (SHARe) by Carty, Cara L., Johnson, Nicholas A., Hutter, Carolyn M., Reiner, Alexander P., Peters, Ulrike, Tang, Hua, Kooperberg, Charles

“…Height is a complex trait under strong genetic influence. To date, numerous genetic loci have been associated with height in individuals of European ancestry…”
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Global bathymetric patterns of standing stock and body size in the deep-sea benthos by Rex, Michael A., Etter, Ron J., Morris, Jeremy S., Crouse, Jenifer, McClain, Craig R., Johnson, Nicholas A., Stuart, Carol T., Deming, Jody W., Thies, Rebecca, Avery, Renee

“…We present the first global-scale analysis of standing stock (abundance and biomass) for 4 major size classes of deep-sea biota: bacteria, metazoan meiofauna,…”
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