Search Results - "Johnson, Lynne"
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1
Death, near death, and an antibiotic
Published in Journal of nuclear cardiology (01-02-2018)Get full text
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Diagnosing Transthyretin Cardiac Amyloidosis by Technetium Tc 99m Pyrophosphate: A Test in Evolution
Published in JACC. Cardiovascular imaging (01-06-2021)“…This study aimed to characterize trends in technetium Tc 99m pyrophosphate ( Tc-PYP) scanning for amyloid transthyretin cardiac amyloidosis (ATTR-CA)…”
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Targeting activated macrophages to identify the vulnerable atherosclerotic plaque
Published in Journal of nuclear cardiology (01-06-2017)Get full text
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Blocking RAGE expression after injury reduces inflammation in mouse model of acute lung injury
Published in Respiratory research (20-01-2023)“…Receptor for Advanced Glycated Endproducts (RAGE) plays a major role in the inflammatory response to infectious and toxin induced acute lung injury. We tested…”
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Agreement of Visual Estimation of Coronary Artery Calcium From Low-Dose CT Attenuation Correction Scans in Hybrid PET/CT and SPECT/CT With Standard Agatston Score
Published in Journal of the American College of Cardiology (30-11-2010)“…Objectives We sought to evaluate the accuracy and reproducibility of visual estimation of coronary artery calcium (CAC) from computed tomography attenuation…”
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Multiple Testing, Cumulative Radiation Dose, and Clinical Indications in Patients Undergoing Myocardial Perfusion Imaging
Published in JAMA : the journal of the American Medical Association (17-11-2010)“…CONTEXT Myocardial perfusion imaging (MPI) is the single medical test with the highest radiation burden to the US population. Although many patients undergoing…”
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Noninvasive Physiologic Assessment of Cardiac Allograft Vasculopathy Is Prognostic for Post-Transplant Events
Published in Journal of the American College of Cardiology (25-10-2022)“…Cardiac allograft vasculopathy (CAV) causes impaired blood flow in both epicardial coronary arteries and the microvasculature. A leading cause of…”
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Scube activity is necessary for Hedgehog signal transduction in vivo
Published in Developmental biology (15-08-2012)“…The Hedgehog (HH) signaling pathway is a central regulator of embryonic development, controlling the pattern and proliferation of a wide variety of organs…”
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Contrast-enhanced ultrasonography to evaluate changes in renal cortical microcirculation induced by noradrenaline: a pilot study
Published in Critical care (London, England) (02-12-2014)“…We used contrast-enhanced ultrasound (CEUS) to estimate the effect of an increase in mean arterial pressure (MAP) induced by noradrenaline infusion on renal…”
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Blocking RAGE improves wound healing in diabetic pigs
Published in International wound journal (01-03-2023)“…Receptor for Advanced Glycated End‐products (RAGE) is highly expressed in diabetes and impairs wound healing. We proposed that administering an antibody that…”
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False Positive 99mTc-Pyrophosphate Scanning Leading to Inappropriate Tafamidis Prescriptions
Published in JACC. Cardiovascular imaging (01-10-2021)Get full text
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12
Novel Receptor for Advanced Glycation End Products-Blocking Antibody to Treat Diabetic Peripheral Artery Disease
Published in Journal of the American Heart Association (05-01-2021)“…Background Expression of receptor for advanced glycation end products (RAGE) plays an important role in diabetic peripheral artery disease. We proposed to show…”
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The importance of SPECT cardiac reconstruction for accurate 99mTc-pyrophosphate interpretation in TTR amyloidosis
Published in Journal of nuclear cardiology (01-06-2022)Get full text
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14
cAMP and cGMP signaling: sensory systems with prokaryotic roots adopted by eukaryotic cilia
Published in Trends in cell biology (01-08-2010)“…An exciting discovery of the new millennium is that primary cilia, organelles found on most eukaryotic cells, play crucial roles in vertebrate development by…”
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Radiation dose and prognosis of ultra-low-dose stress-first myocardial perfusion SPECT in patients with chest pain using a high-efficiency camera
Published in Journal of Nuclear Medicine (01-04-2015)“…Although SPECT myocardial perfusion imaging (MPI) provides valuable information about patients with chest pain, there is growing concern regarding its…”
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Diagnostic performance characteristics of planar quantitative and semi-quantitative parameters of Tc99m pyrophosphate (PYP) imaging for diagnosis of transthyretin (ATTR) cardiac amyloidosis: the SCAN-MP study
Published in Journal of nuclear cardiology (01-08-2023)“…The optimal heart-to-contralateral chest (H/CL) ratio threshold for non-invasive diagnosis of transthyretin cardiac amyloidosis (ATTR-CA) using Tc99m…”
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Imaging atherosclerosis and vulnerable plaque
Published in Journal of Nuclear Medicine (01-05-2010)“…Identifying patients at high risk for an acute cardiovascular event such as myocardial infarction or stroke and assessing the total atherosclerotic burden are…”
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Single-photon emission computed tomography/computed tomography imaging of RAGE in smoking-induced lung injury
Published in Respiratory research (10-06-2019)“…Expression of the Receptor for Advanced Glycation Endproducts (RAGE) initiates pro-inflammatory pathways resulting in lung destruction. We hypothesized that…”
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Prevalence and significance of extracardiac uptake on pyrophosphate imaging in the SCAN-MP study: the first 379 cases
Published in Journal of nuclear cardiology (01-12-2023)“…Technetium-labeled bone-avid radiotracers can be used to diagnose transthyretin cardiac amyloidosis (ATTR-CA). Extracardiac uptake of technetium pyrophosphate…”
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Selective Imaging of Vascular Endothelial Growth Factor Receptor-1 and Receptor-2 in Atherosclerotic Lesions in Diabetic and Non-diabetic ApoE−/− Mice
Published in Molecular imaging and biology (01-02-2018)“…Purpose Plaque vulnerability is associated with inflammation and angiogenesis, processes that rely on vascular endothelial growth factor (VEGF) signaling via…”
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