Search Results - "Johnson, Kendall R."

Alarm Safety and Alarm Fatigue by Johnson, Kendall R., MD, Hagadorn, James I., MD, MS, Sink, David W., MD

“…Clinical alarm systems have received significant attention in recent years following warnings from hospital accrediting and health care technology…”
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Native Capillary Electrophoresis–Mass Spectrometry of Near 1 MDa Non‐Covalent GroEL/GroES/Substrate Protein Complexes by Marie, Anne‐Lise, Georgescauld, Florian, Johnson, Kendall R., Ray, Somak, Engen, John R., Ivanov, Alexander R.

“…Protein complexes are essential for proteins' folding and biological function. Currently, native analysis of large multimeric protein complexes remains…”
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On-capillary Cell Lysis Enables Top-down Proteomic Analysis of Single Mammalian Cells by CE-MS/MS by Johnson, Kendall R., Gao, Yunfan, Greguš, Michal, Ivanov, Alexander R.

“…Proteomic analysis of limited samples and single cells requires specialized methods that prioritize high sensitivity and minimize sample loss. Consequently,…”
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Single-cell omic molecular profiling using capillary electrophoresis-mass spectrometry by Bagwe, Ketki, Gould, Noah, Johnson, Kendall R., Ivanov, Alexander R.

“…Tissues and other cell populations are highly heterogeneous at the cellular level, owing to differences in expression and modifications of proteins,…”
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Coupling High-Field Asymmetric Ion Mobility Spectrometry with Capillary Electrophoresis-Electrospray Ionization-Tandem Mass Spectrometry Improves Protein Identifications in Bottom-Up Proteomic Analysis of Low Nanogram Samples by Johnson, Kendall R., Greguš, Michal, Ivanov, Alexander R.

“…In this work, we pioneered the assessment of coupling high-field asymmetric waveform ion mobility spectrometry (FAIMS) with ultrasensitive capillary…”
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Capillary Electrophoresis Coupled to Electrospray Ionization Tandem Mass Spectrometry for Ultra-Sensitive Proteomic Analysis of Limited Samples by Johnson, Kendall R, Greguš, Michal, Kostas, James C, Ivanov, Alexander R

“…In this work, we developed an ultra-sensitive CE-MS/MS method for bottom-up proteomics analysis of limited samples, down to sub-nanogram levels of total…”
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Best practices and benchmarks for intact protein analysis for top-down mass spectrometry by Donnelly, Daniel P., Rawlins, Catherine M., DeHart, Caroline J., Fornelli, Luca, Schachner, Luis F., Lin, Ziqing, Lippens, Jennifer L., Aluri, Krishna C., Sarin, Richa, Chen, Bifan, Lantz, Carter, Jung, Wonhyeuk, Johnson, Kendall R., Koller, Antonius, Wolff, Jeremy J., Campuzano, Iain D. G., Auclair, Jared R., Ivanov, Alexander R., Whitelegge, Julian P., Paša-Tolić, Ljiljana, Chamot-Rooke, Julia, Danis, Paul O., Smith, Lloyd M., Tsybin, Yury O., Loo, Joseph A., Ge, Ying, Kelleher, Neil L., Agar, Jeffrey N.

“…One gene can give rise to many functionally distinct proteoforms, each of which has a characteristic molecular mass. Top-down mass spectrometry enables the…”
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Trends and variation in management and outcomes of very low-birth-weight infants with patent ductus arteriosus by Hagadorn, James I., Brownell, Elizabeth A., Trzaski, Jennifer M., Johnson, Kendall R., Lainwala, Shabnam, Campbell, Brendan T., Herbst, Katherine W.

“…Background: We examined recent trends and interhospital variation in use of indomethacin, ibuprofen, and surgical ligation for patent ductus arteriosus (PDA)…”
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Improving the quality of quality metrics in neonatology by Hagadorn, James I., Johnson, Kendall R., Hill, Deanna, Sink, David W.

“…This article examines approaches for improving the efficiency and effectiveness of quality metrics currently in use in neonatal care. Desirable characteristics…”
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Development of High-Sensitivity Ce-Esi-Ms-Based Methods for Proteomic Profiling of Limited Samples and Single Cells by Johnson, Kendall R

“…The mass spectrometry (MS)-based ‘omics’ approach to protein analysis enables high-throughput profiling of the proteome, providing a rich data set of protein…”
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Best practices and benchmarks for intact protein analysis for top-down mass spectrometry by Donnelly, Daniel P., Rawlins, Catherine M., DeHart, Caroline J., Fornelli, Luca, Schachner, Luis F., Lin, Ziqing, Lippens, Jennifer L., Aluri, Krishna C., Sarin, Richa, Chen, Bifan, Lantz, Carter, Jung, Wonhyeuk, Johnson, Kendall R., Koller, Antonius, Wolff, Jeremy J., Campuzano, Iain D. G., Auclair, Jared R., Ivanov, Alexander R., Whitelegge, Julian P., Paša-Tolić, Ljiljana, Chamot-Rooke, Julia, Danis, Paul O., Smith, Lloyd M., Tsybin, Yury O., Loo, Joseph A., Ge, Ying, Kelleher, Neil L., Agar, Jeffrey N.

“…One gene can give rise to many functionally distinct proteoforms, each of which has a characteristic molecular mass. Many laboratories, however, forgo the…”
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