Search Results - "Johnson, HM"

Abstract P6-08-21: Early breast cancer-specific mortality in women with early stage breast cancer: Epidemiological and clinical characteristics by Johnson, HM, Wong, JH, Vohra, NA, Muzaffar, M

“…Background and Aim: The five-year survival for women with stage I-II breast cancer is 93-100%. Despite standard of care treatment, a small subset of these…”
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Abstract P5-11-12: Longitudinal changes in volumetric breast density and fibroglandular volume with endocrine therapy in African American women with estrogen receptor positive breast cancer by Johnson, HM, Shivalingappa, H, Wong, JH, Muzaffar, M, Verbanac, K, Vohra, NA

“…Background and Aim: Reduction in breast density has been proposed as a biomarker of response to endocrine therapy (ET). The vast majority of current data are…”
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The acceptability of an information leaflet explaining cardiopulmonary resuscitation policy in the hospice setting: a qualitative study exploring patients’ views by Johnson, HM, Nelson, A

“…Background: Guidelines advise that patients receiving palliative care should be given realistic information about cardiopulmonary resuscitation (CPR) and…”
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A SOCS-1 peptide mimetic inhibits both constitutive and IL-6 induced activation of STAT3 in prostate cancer cells by FLOWERS, Lawrence O, SUBRAMANIAM, Prem S, JOHNSON, Howard M

“…Prostate cancer is the second highest cause of cancer-related deaths of men in the US. Signal transducers and activators of transcription (STATs) proteins are…”
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Trafficking and signaling pathways of nuclear localizing protein ligands and their receptors by Johnson, Howard M., Subramaniam, Prem S., Olsnes, Sjur, Jans, David A.

“…Interaction of ligands such as epidermal growth factor and interferon‐γ with the extracellular domains of their plasma membrane receptors results in…”
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IFN-gamma and its receptor subunit IFNGR1 are recruited to the IFN-gamma-activated sequence element at the promoter site of IFN-gamma-activated genes: evidence of transactivational activity in IFNGR1 by Ahmed, Chulbul M I, Johnson, Howard M

“…We have shown previously that IFN-gamma and one of its receptor subunits, IFNGR1, are translocated to the nucleus, together with STAT1alpha as one…”
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Agonist properties of a microbial superantigen peptide by Pontzer, C H, Griggs, N D, Johnson, H M

“…Staphylococcal enterotoxin A (SEA) binds to class II major histocompatibility complex (MHC) molecules and stimulates monocytes to produce tumor necrosis factor…”
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Characterization of a Peptide Inhibitor of Janus Kinase 2 That Mimics Suppressor of Cytokine Signaling 1 Function by Flowers, Lawrence O, Johnson, Howard M, Mujtaba, Mustafa G, Ellis, Morgan R, Haider, S. Mohammed I, Subramaniam, Prem S

“…Positive and negative regulation of cytokines such as IFN-gamma are key to normal homeostatic function. Negative regulation of IFN-gamma in cells occurs via…”
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Treatment of Mice with the Suppressor of Cytokine Signaling-1 Mimetic Peptide, Tyrosine Kinase Inhibitor Peptide, Prevents Development of the Acute Form of Experimental Allergic Encephalomyelitis and Induces Stable Remission in the Chronic Relapsing/Remitting Form by Mujtaba, Mustafa G, Flowers, Lawrence O, Patel, Chintak B, Patel, Ravi A, Haider, Mohammad I, Johnson, Howard M

“…We have previously characterized a novel tyrosine kinase inhibitor peptide (Tkip) that is a mimetic of suppressor of cytokine signaling 1 (SOCS-1) and inhibits…”
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Sources of the Continued Influence Effect: When Misinformation in Memory Affects Later Inferences by Johnson, Hollyn M, Seifert, Colleen M

“…Several lines of research have found that information previously encoded into memory can influence inferences and judgments, even when more recent information…”
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Lipid Microdomains Are Required Sites for the Selective Endocytosis and Nuclear Translocation of IFN-γ, Its Receptor Chain IFN-γ Receptor-1, and the Phosphorylation and Nuclear Translocation of STAT1α by Subramaniam, Prem S., Johnson, Howard M.

“…IFN-γ contains a nuclear localization sequence that may play a role in the nuclear transport of activated STAT1α via a complex of IFN-γ/IFN-γ receptor…”
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Processes of Successful Intentional Forgetting by Johnson, Hollyn M

“…This article presents a framework, based on directed forgetting and social judgment research, for understanding compliance with overt instructions to disregard…”
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Prospective analysis of the outcome of surgical management of drooling in the pediatric population : A 10-year experience by GREENSMITH, Andrew L, JOHNSTONE, Bruce R, REID, Susan M, HAZARD, Catherine J, JOHNSON, Hilary M, REDDIHOUGH, Dinah S

“…Sialorrhea is a common problem in the neurologically impaired pediatric patient and surgery is the mainstay of treatment for severely affected patients…”
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The role of IFNγ nuclear localization sequence in intracellular function by Ahmed, C. M. Iqbal, Burkhart, Marjorie A., Mujtaba, Mustafa G., Subramaniam, Prem S., Johnson, Howard M.

“…Intracellularly expressed interferon γ (IFNγ) has been reported to possess biological activity similar to that of IFNγ added to cells. This study addresses the…”
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Cutting edge: oral type I IFN-tau promotes a Th2 bias and enhances suppression of autoimmune encephalomyelitis by oral glatiramer acetate by Soos, Jeanne M, Stüve, Olaf, Youssef, Sawsan, Bravo, Manuel, Johnson, Howard M, Weiner, Howard L, Zamvil, Scott S

“…IFN-tau, a novel type I IFN that possesses immunomodulatory properties, lacks toxicity normally associated with other type I IFNs. We examined the effects of…”
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So many ligands, so few transcription factors: a new paradigm for signaling through the STAT transcription factors by Subramaniam, P S, Torres, B A, Johnson, H M

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Effectiveness of the Innsbruck Sensorimotor Activator and Regulator in improving saliva control in children with cerebral palsy by Johnson, Hilary M, Reid, Susan M, Hazard, Catherine J, Lucas, James O, Desai, Mala, Reddihough, Dinah S

“…The aim of this study was to determine the effectiveness of an intraoral appliance, the Innsbruck Sensorimotor Activator and Regulator (ISMAR), in improving…”
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The Carboxyl Terminus of Interferon-γ Contains a Functional Polybasic Nuclear Localization Sequence by Subramaniam, Prem S., Mujtaba, Mustafa G., Paddy, Michael R., Johnson, Howard M.

“…Cytokines such as interferon-gamma (IFN-γ), which utilize the well studied JAK/STAT pathway for nuclear signal transduction, are themselves translocated to the…”
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Superantigens: the good, the bad, and the ugly by Torres, B A, Kominsky, S, Perrin, G Q, Hobeika, A C, Johnson, H M

“…Increasing evidence suggests that superantigens play a role in immune-mediated diseases. Superantigens are potent activators of CD4+ T cells, causing rapid and…”
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Mechanism of Interleukin-10 Inhibition of T-Helper Cell Activation by Superantigen at the Level of the Cell Cycle by Perrin, George Q., Johnson, Howard M., Subramaniam, Prem S.

“…We have analyzed the effects of interleukin-10 (IL-10) on the entry of quiescent CD4+ T cells into the cell cycle upon stimulation with the superantigen…”
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